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The Journal of Maternal-Fetal & Neonatal Medicine Volume 34, 2021 - Issue 23
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Original Articles

TREC and KREC in very preterm infants: reference values and effects of maternal and neonatal factors

Giulia Remaschia Division of Neonatology, Careggi University Hospital of Florence, Florence, Italy
,
Silvia Riccib Division of Pediatric Immunology, Department of Pediatrics, Meyer Children’s University Hospital, Florence, Italy;c Department of Health Sciences, Meyer University Hospital, University of Florence, Florence, Italy
,
Martina Cortimigliab Division of Pediatric Immunology, Department of Pediatrics, Meyer Children’s University Hospital, Florence, Italy
,
Elisa De Vitisb Division of Pediatric Immunology, Department of Pediatrics, Meyer Children’s University Hospital, Florence, Italy
,
Laura Iannuzzid Margherita Birth Center, Careggi University Hospital of Florence, Florence, Italy
,
Luca Bonie Clinical Trials Coordinating Center, Careggi University Teaching Hospital of Florence, Florence, Italy
,
Chiara Azzarib Division of Pediatric Immunology, Department of Pediatrics, Meyer Children’s University Hospital, Florence, Italy;c Department of Health Sciences, Meyer University Hospital, University of Florence, Florence, ItalyORCID Iconhttps://orcid.org/0000-0001-7236-1655
ORCID Icon &
Carlo Dania Division of Neonatology, Careggi University Hospital of Florence, Florence, Italy;f Department of Neurosciences, Psychology, Drug Research and Child Health, University of Florence, Italy FlorenceCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-1639-621X
ORCID Icon show all
Pages 3946-3951 | Received 22 Jul 2019, Accepted 06 Dec 2019, Published online: 29 Dec 2019

References

  • Pai SY, Logan BR, Griffith LM, et al. Transplantation outcomes for severe combined immunodeficiency, 2000–2009. N Engl J Med. 2014;371(5):434–446.
  • Serana F, Chiarini M, Zanotti C, et al. Use of V(D)J recombination excision circles to identify T- and B-cell defects and to monitor the treatment in primary and acquired immunodeficiencies. J Transl Med. 2013;11(1):119.
  • Chan K, Puck JM. Development of population-based newborn screening for severe combined immunodeficiency. J Allergy Clin Immunol. 2005;115(2):391–398.
  • Routes J, Verbsky J. Newborn screening for severe combined immunodeficiency. Curr Allergy Asthma Rep. 2018;18(6):34.
  • King JR, Hammarström L. Newborn screening for primary immunodeficiency diseases: history, current and future practice. J Clin Immunol. 2018;38(1):56–66.
  • Kwan A, Abraham RS, Currier R, et al. Newborn screening for severe combined immunodeficiency in 11 screening programs in the United States. J Am Med Assoc. 2014;312(7):729–738.
  • Routes JM, Grossman WJ, Verbsky J, et al. Statewide newborn screening for severe T-cell lymphopenia. J Am Med Assoc. 2009;302(22):2465–2470.
  • Baker MW, Grossman WJ, Laessig RH, et al. Development of a routine newborn screening protocol for severe combined immunodeficiency. J Allergy Clin Immunol. 2009;124(3):522–527.
  • Lodi L, Ricci S, Romano F, et al. Newborn screening for PIDs using both TREC and KREC identifies late occurrence of B cells. Pediatr Allergy Immunol. 2017;28(5):498–500.
  • Borte S, von Döbeln U, Fasth A, et al. Neonatal screening for severe primary immunodeficiency diseases using high-throughput triplex real-time PCR. Blood. 2012;119(11):2552–2555.
  • Verbsky J, Thakar M, Routes J. The Wisconsin approach to newborn screening for severe combined immunodeficiency. J Allergy Clin Immunol. 2012;129(3):622–627.
  • Barbaro M, Ohlsson A, Borte S, et al. Newborn screening for severe primary immunodeficiency diseases in Sweden-a 2-year pilot TREC and KREC screening study. J Clin Immunol. 2017;37(1):51–60.
  • Rechavi E, Lev A, Simon AJ, et al. First year of Israeli newborn screening for severe combined immunodeficiency-clinical achievements and insights. Front Immunol. 2017;8:1448
  • Ward CE, Baptist AP. Challenges of newborn severe combined immunodeficiency screening among premature infants. Pediatrics. 2013;131(4):e1298–e1302.
  • Forestier F, Daffos F, Catherine N, et al. Developmental hematopoiesis in normal human fetal blood. Blood. 1991;77(11):2360–2363.
  • Darmochwal-Kolarz D, Leszczynska-Gorzelak B, Rolinski J, et al. Pre-eclampsia affects the immunophenotype of neonates. Immunol Lett. 2001;77(2):67–71.
  • Bolat A, Gursel O, Kurekci E, et al. Blood parameters changes in cord blood of newborns of hypertensive mothers. Eur J Pediatr. 2013;172(11):1501–1509.
  • Sava F, Toldi G, Treszl A, et al. Immune cell subsets, cytokine and cortisol levels during the first week of life in neonates born to pre-eclamptic mothers. Am J Reprod Immunol. 2017;77(6):e12659.
  • Strunk T, Doherty D, Jacques A, et al. Histologic chorioamnionitis is associated with reduced risk of late-onset sepsis in preterm infants. Pediatrics. 2012;129(1):e134–e141.
  • De Felice C, Toti P, Santopietro R, et al. Small thymus in very low birth weight infants born to mothers with subclinical chorioamnionitis. J Pediatr. 1999;135(3):384–386.

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