Advanced search
Publication Cover
The Journal of Maternal-Fetal & Neonatal Medicine Volume 35, 2022 - Issue 16
Submit an article Journal homepage
245
Views
1
CrossRef citations to date
0
Altmetric
Original Article

Placental growth factor as a predictive marker of preeclampsia – PREBIO study – PREeclampsia BIOchemical study

Valentina GiardiniDepartment of Obstetrics and Gynecology, University of Milano-Bicocca, MBBM Foundation, S. Gerardo Hospital, Monza, ItalyCorrespondence[email protected]
,
Roberta RovelliDepartment of Obstetrics and Gynecology, University of Milano-Bicocca, MBBM Foundation, S. Gerardo Hospital, Monza, Italy
,
Paola AlgeriDepartment of Obstetrics and Gynecology, University of Milano-Bicocca, MBBM Foundation, S. Gerardo Hospital, Monza, Italy
,
Laura GiuntiDepartment of Obstetrics and Gynecology, University of Milano-Bicocca, MBBM Foundation, S. Gerardo Hospital, Monza, Italy
,
Sara LazzarinDepartment of Obstetrics and Gynecology, University of Milano-Bicocca, MBBM Foundation, S. Gerardo Hospital, Monza, Italy
,
Clelia CallegariDepartment of Obstetrics and Gynecology, University of Milano-Bicocca, MBBM Foundation, S. Gerardo Hospital, Monza, Italy
,
Nadia RoncagliaDepartment of Obstetrics and Gynecology, University of Milano-Bicocca, MBBM Foundation, S. Gerardo Hospital, Monza, Italy
&
Patrizia VerganiDepartment of Obstetrics and Gynecology, University of Milano-Bicocca, MBBM Foundation, S. Gerardo Hospital, Monza, Italy
 show all
Pages 3029-3035 | Received 20 Dec 2019, Accepted 03 Jul 2020, Published online: 20 Jul 2020

References

  • Mol BWJ, Roberts CT, Thangaratinam S, et al. Pre-eclampsia. Lancet. 2016;387(10022):999–1011. http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(15)00070-7/fulltext#.WiuWBr0ztkE.mendeley.
  • Roberts JM, August PA, Bakris G, et al. Hypertension in pregnancy. Report of the American College of Obstetricians and Gynecologists’ Task Force on Hypertension in Pregnancy. Obstet Gynecol. 2013;122(5):1122–1131.
  • Huppertz B. Placental origins of preeclampsia: challenging the current hypothesis. Hypertension. 2008;51(4):970–975.
  • Verlohren S, Stepan H, Dechend R. Angiogenic growth factors in the diagnosis and prediction of pre-eclampsia. Clin Sci. 2012;122(2):43–52.
  • Sahai K, Saraswathy S, Yadav TP, et al. Pre-eclampsia: molecular events to biomarkers. Med J Armed Forces India. 2017;73(2):167–174. [cited 2017 Dec 9]Available from: http://www.ncbi.nlm.nih.gov/pubmed/28924318.
  • Ukah UV, Hutcheon JA, Payne B, et al. Placental growth factor as a prognostic tool in women with hypertensive disorders of pregnancy: a systematic review. Hypertension. 2017;70(6):1228–1237.
  • Adamson SL. SFLT1 in preeclampsia: trophoblast defense against a decidual VEGFA barrage? J Clin Invest. 2014;124(11):4690–4692.
  • Saffer C, Olson G, Boggess KA, et al. Determination of placental growth factor (PlGF) levels in healthy pregnant women without signs or symptoms of preeclampsia. Pregnancy Hypertens. 2013;3(2):124–132.
  • Rădulescu C, Bacârea A, Huțanu A, et al. Placental growth factor, soluble fms-like tyrosine kinase 1, soluble endoglin, IL-6, and IL-16 as biomarkers in preeclampsia. Mediators Inflamm. 2016;2016:3027363.
  • Chappell LC, Duckworth S, Griffin M, et al. OS100. Plasma placental growth factor (PLGF) measurement in women presenting with suspected pre-eclampsia: the pelican study. Pregnancy Hypertens. 2012;2(3):233–234.
  • Redman C. Diagnostic and predictive accuracy of placental growth factor in suspected pre-eclampsia. Pregnancy Hypertens. 2014;4(3):241.
  • Zeisler H, Llurba E, Chantraine F, et al. Predictive value of the sFlt-1:PlGF ratio in women with suspected preeclampsia. N Engl J Med. 2016;374(1):13–22.
  • NICE. PlGF-based testing to help diagnose suspected pre-eclampsia (Triage PlGF test, Elecsys immunoassay sFlt-1/PlGF ratio, DELFIA Xpress PlGF 1-2-3 test, and BRAHMS sFlt-1 Kryptor/BRAHMS PlGF plus Kryptor PE ratio). Diagnostic Guid 23. 2016.
  • [cited 2020 July 7]. Available from: http://www.awmf.org/uploads/tx_szleitlinien/037-012l_S1_Lipoedem_2016-01.pdf.
  • Bertino E, Spada E, Occhi L, et al. Neonatal anthropometric charts: the Italian neonatal study compared with other European studies. J Pediatr Gastroenterol Nutr. 2010;51(3):353–361.
  • Gordijn SJ, Beune IM, Thilaganathan B, et al. Consensus definition of fetal growth restriction: a Delphi procedure. Ultrasound Obstet Gynecol. 2016;48(3):333–339.
  • Von See J, Limperger V, Pecks U, et al. Influences on Placental Growth Factor (PlGF) and soluble fms-like tyrosine kinase-1 (sFlt-1) concentration levels at the time of first trimester screening. Z Geburtshilfe Neonatol. 2016;220(04):166–172.
  • Meher A, Sundrani D, Joshi S. Maternal nutrition influences angiogenesis in the placenta through peroxisome proliferator activated receptors: a novel hypothesis. Mol Reprod Dev. 2015;82(10):726–734.
  • Eleftheriades M, Papastefanou I, Lambrinoudaki I, et al. Elevated placental growth factor concentrations at 11–14 weeks of gestation to predict gestational diabetes mellitus. Metabolism. 2014;63(11):1419–1425.
  • Huynh J, Dawson D, Roberts D, et al. A systematic review of placental pathology in maternal diabetes mellitus. Placenta. 2015;36(2):101–114.
  • Mosimann B, Amylidi S, Risch L, et al. First-trimester placental growth factor in screening for gestational diabetes. Fetal Diagn Ther. 2016;39(4):287–291.
  • Benton SJ, McCowan LM, Heazell AEP, et al. Placental growth factor as a marker of fetal growth restriction caused by placental dysfunction. Placenta. 2016;42:1–8.
  • Triunfo S, Lobmaier S, Parra-Saavedra M, et al. Angiogenic factors at diagnosis of late-onset small-for-gestational age and histological placental underperfusion. Placenta. 2014;35(6):398–403.
  • Redman CWG, Staff AC. Preeclampsia, biomarkers, syncytiotrophoblast stress, and placental capacity. Am J Obstet Gynecol. 2015;213(4):S9.e1–S9.e4.
  • Vatish M, Strunz-McKendry T, Hund M, et al. sFlt-1/PlGF ratio test for pre-eclampsia: an economic assessment for the UK. Ultrasound Obstet Gynecol. 2016;48(6):765–771.
  • Duckworth S, Chappell LC, Seed PT, et al. Placental growth factor (PLGF) in women with suspected pre-eclampsia prior to 35 weeks’ gestation: a budget impact analysis. PLoS One. 2016;11(10):e0164276.
  • Cox LS, Redman C. The role of cellular senescence in ageing of the placenta. Placenta. 2017;52:139–145.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.