309
Views
6
CrossRef citations to date
0
Altmetric
Original Articles

Antenatal corticosteroids and the influence of sex on morbidity and mortality of preterm infants

ORCID Icon, ORCID Icon, &
Pages 3438-3445 | Received 13 Aug 2020, Accepted 02 Sep 2020, Published online: 15 Sep 2020

References

  • Effect of corticosteroids for fetal maturation on perinatal outcomes. NIH Consensus Statement. 1994;12(2):1–24.
  • Roberts D, Brown J, Medley N, et al. Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth. Cochrane Database Syst Rev. 2017;3:CD004454.
  • Jobe AH. Neonatal stress and resilience – lasting effects of antenatal corticosteroids. Can J Physiol Pharmacol. 2019;97(3):155–157.
  • Redline RW. Classification of placental lesions. Am J Obstet Gynecol. 2015;213(4 Suppl.):S21–S28.
  • The CRIB (clinical risk index for babies) score: a tool for assessing initial neonatal risk and comparing performance of neonatal intensive care units. The International Neonatal Network. Lancet. 1993;342(8865):193–198.
  • Jobe AH, Bancalari E. Bronchopulmonary dysplasia. Am J Respir Crit Care Med. 2001;163(7):1723–1729.
  • Walsh MC, Yao Q, Gettner P, et al. Impact of a physiologic definition on bronchopulmonary dysplasia rates. Pediatrics. 2004;114(5):1305–1311.
  • de Vries LS, Eken P, Groenendaal F, et al. Correlation between the degree of periventricular leukomalacia diagnosed using cranial ultrasound and MRI later in infancy in children with cerebral palsy. Neuropediatrics. 1993;24(5):263–268.
  • Volpe JJ. Neurology of the newborn. 5th ed. Philadelphia: Saunders/Elsevier; 2008.
  • Papile LA, Burstein J, Burstein R, et al. Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1,500 gm. J Pediatr. 1978;92(4):529–534.
  • Josse DP-M. Brunet-Lézine revisado. Escala de desarrollo psicomotor de la primera infancia. Madrid: Symtéc; 1998.
  • Garcia-Munoz Rodrigo F, Losada Martinez A, Elorza Fernandez MD, et al. The burden of respiratory disease in very-low-birth-weight infants: changes in perinatal care and outcomes in a decade in Spain. Neonatology. 2017;112(1):30–39.
  • Helenius K, Sjors G, Shah PS, et al. Survival in very preterm infants: an international comparison of 10 national neonatal networks. Pediatrics. 2017;140(6):e20171264.
  • Travers S, Martinerie L, Boileau P, et al. Alterations of adrenal steroidomic profiles in preterm infants at birth. Arch Dis Child Fetal Neonatal Ed. 2018;103(2):F143–F151.
  • Manktelow BN, Lal MK, Field DJ, et al. Antenatal corticosteroids and neonatal outcomes according to gestational age: a cohort study. Arch Dis Child Fetal Neonatal Ed. 2010;95(2):F95–F98.
  • Rodriguez JS, Zurcher NR, Keenan KE, et al. Prenatal betamethasone exposure has sex specific effects in reversal learning and attention in juvenile baboons. Am J Obstet Gynecol. 2011;204(6):545.e1–545.e10.
  • Kemp MW, Jobe AH, Usuda H, et al. Efficacy and safety of antenatal steroids. Am J Physiol Regul Integr Comp Physiol. 2018;315:R825–R839.
  • Lee JY, Yun HJ, Kim CY, et al. Prenatal exposure to dexamethasone in the mouse induces sex-specific differences in placental gene expression. Dev Growth Differ. 2017;59(6):515–525.
  • Wieczorek A, Perani CV, Nixon M, et al. Sex-specific regulation of stress-induced fetal glucocorticoid surge by the mouse placenta. Am J Physiol Endocrinol Metab. 2019;317(1):E109–E120.
  • Guo J, Fang M, Zhuang S, et al. Prenatal dexamethasone exposure exerts sex-specific effect on placental oxygen and nutrient transport ascribed to the differential expression of IGF2. Ann Transl Med. 2020;8(5):233.
  • Braun F, Hardt AK, Ehrlich L, et al. Sex-specific and lasting effects of a single course of antenatal betamethasone treatment on human placental 11β-HSD2. Placenta. 2018;69:9–19.
  • Wynne-Edwards KE, Lee K, Zhou R, et al. Sex differences in substrates and clearance products of cortisol and corticosterone synthesis in full-term human umbilical circulation without labor: substrate depletion matches synthesis in males, but not females. Psychoneuroendocrinology. 2019;109:104381.
  • Lorente-Pozo S, Parra-Llorca A, Torres B, et al. Influence of sex on gestational complications, fetal-to-neonatal transition, and postnatal adaptation. Front Pediatr. 2018;6:63.
  • Kotecha SJ, Lowe J, Kotecha S. Does the sex of the preterm baby affect respiratory outcomes? Breathe (Sheff). 2018;14(2):100–107.
  • Stevenson DK, Verter J, Fanaroff AA, et al. Sex differences in outcomes of very low birthweight infants: the newborn male disadvantage. Arch Dis Child Fetal Neonatal Ed. 2000;83(3):F182–F185.
  • Hintz SR, Kendrick DE, Vohr BR, et al. Gender differences in neurodevelopmental outcomes among extremely preterm, extremely-low-birthweight infants. Acta Paediatr. 2006;95(10):1239–1248.
  • Doyle LW, Ehrenkranz RA, Halliday HL. Early (<8 days) postnatal corticosteroids for preventing chronic lung disease in preterm infants. Cochrane Database Syst Rev. 2014;5:CD001146.
  • Massaro D, Massaro GD. Dexamethasone accelerates postnatal alveolar wall thinning and alters wall composition. Am J Physiol. 1986;251(2 Pt 2):R218–R224.
  • Hjalmarson O, Sandberg KL. Effect of antenatal corticosteroid treatment on lung function in full-term newborn infants. Neonatology. 2011;100(1):32–36.
  • Jobe AH. Prenatal and postnatal steroids and pulmonary outcomes. The newborn lung. Neonatology questions and controversies. 3rd ed. In: Eduardo Bancalari, editor. Ámsterdam: Elsevier; 2018. p. 335–346.
  • Bandyopadhyay A, Slaven JE, Evrard C, et al. Antenatal corticosteriods decrease forced vital capacity in infants born fullterm. Pediatr Pulmonol. 2020. 1–5.
  • Braun T, Challis JR, Newnham JP, et al. Early-life glucocorticoid exposure: the hypothalamic-pituitary-adrenal axis, placental function, and long-term disease risk. Endocr Rev. 2013;34(6):885–916.
  • Zurcher NR, Rodriguez JS, Jenkins SL, et al. Performance of juvenile baboons on neuropsychological tests assessing associative learning, motivation and attention. J Neurosci Methods. 2010;188(2):219–225.
  • Alexander N, Rosenlocher F, Stalder T, et al. Impact of antenatal synthetic glucocorticoid exposure on endocrine stress reactivity in term-born children. J Clin Endocrinol Metabol. 2012;97(10):3538–3544.
  • Murphy KE, Willan AR, Hannah ME, et al. Effect of antenatal corticosteroids on fetal growth and gestational age at birth. Obstet Gynecol. 2012;119(5):917–923.
  • Jobe AH, Goldenberg RL. Antenatal corticosteroids: an assessment of anticipated benefits and potential risks. Am J Obstet Gynecol. 2018;219(1):62–74.
  • Jobe AH. Antenatal corticosteroids—a concern for lifelong outcomes. J Pediatr. 2020;217:184–188.
  • Dixon CL, Too G, Saade GR, et al. Past and present: a review of antenatal corticosteroids and recommendations for late preterm birth steroids. Am J Perinatol. 2018;35(13):1241–1250.
  • Zephyrin LC, Hong KN, Wapner RJ, et al. Gestational age-specific risks vs benefits of multicourse antenatal corticosteroids for preterm labor. Am J Obstet Gynecol. 2013;209(4):330.e1–330.e7.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.