Advanced search
Publication Cover
The Journal of Maternal-Fetal & Neonatal Medicine Volume 35, 2022 - Issue 18
Submit an article Journal homepage
186
Views
3
CrossRef citations to date
0
Altmetric
Original Articles

The clinical utility of D-dimer/platelet count ratio in pregnant women

G. Limontaa Department of Laboratory Medicine, University of Milano-Bicocca, Azienda Socio Sanitaria Territoriale di Monza ASST-Monza, Desio Hospital, Desio, Italy
,
J. Intrab Clinical Chemistry Laboratory, University of Milano-Bicocca, Azienda Socio Sanitaria Territoriale di Monza ASST-Monza, St Gerardo Hospital, Monza, ItalyCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-0978-9573
ORCID Icon &
P. Brambillaa Department of Laboratory Medicine, University of Milano-Bicocca, Azienda Socio Sanitaria Territoriale di Monza ASST-Monza, Desio Hospital, Desio, Italy
Pages 3602-3611 | Received 11 Sep 2019, Accepted 04 Oct 2020, Published online: 19 Feb 2021

References

  • American College of Obstetricians and Gynecologists. ACOG Practice Bulletin No. 125: chronic hypertension in pregnancy. Obstet Gynecol. 2012;119:396–407.
  • English FA, Kenny LC, McCarthy FP. Risk factors and effective management of preeclampsia. Integr Blood Press Control. 2015;8:7–12.
  • Comeglio P, Fedi S, Liotta AA, et al. Blood clotting activation during normal pregnancy. Thromb Res. 1996;84(3):199–202.
  • Bellart J, Gilabert R, Fontcuberta J, et al. Coagulation and fibrinolysis parameters in normal pregnancy and in gestational diabetes. Am J Perinatol. 1998;15(8):479–486.
  • Lippi G, Favaloro EJ, Cervellin G. A review of the value of D-dimer testing for prediction of recurrent venous thromboembolism with increasing age. Semin Thromb Hemost. 2014;40(6):634–639.
  • Pulivarthi S, Gurram MK. Effectiveness of D-dimer as a screening test for venous thromboembolism: an update. N Am J Med Sci. 2014;6(10):491–499.
  • Kim SJ, Ahn HJ, Park JY, et al. The clinical significance of D-dimer concentrations in patients with gestational hypertensive disorders according to the severity. Obstet Gynecol Sci. 2017;60(6):542–548.
  • Kawaguchi S, Yamada T, Takeda M, et al. Changes in D-dimer levels in pregnant women according to gestational week. Pregnancy Hypertens. 2013;3(3):172–177.
  • Wang M, Lu S, Li S, et al. Reference intervals of D-dimer during the pregnancy and puerperium period on the STA-R evolution coagulation analyzer. Clin Chim Acta. 2013;425:176–180.
  • Cui C, Yang S, Zhang J, et al. Trimester-specific coagulation and anticoagulation reference intervals for healthy pregnancy. Thromb Res. 2017;156:82–86.
  • Jin Y, Lu J, Jin H, et al. Reference intervals for biochemical, haemostatic and haematological parameters in healthy Chinese women during early and late pregnancy. Clin Chem Lab Med. 2018;56(6):973–979.
  • Chen Y, Lin L. Potential value of coagulation parameters for suggesting preeclampsia during the third trimester of pregnancy. Am J Med Sci. 2017;354(1):39–43.
  • Szecsi PB, Jørgensen M, Klajnbard A, et al. Haemostatic reference intervals in pregnancy. Thromb Haemost. 2010;103(4):718–727.
  • Hedengran KK, Andersen MR, Stender S, et al. Large D-dimer fluctuation in normal pregnancy: a longitudinal cohort study of 4,117 samples from 714 healthy Danish Women. Obstet Gynecol Int. 2016;2016:3561675.
  • Kovac M, Mikovic Z, Rakicevic L, et al. The use of D-dimer with new cutoff can be useful in diagnosis of venous thromboembolism in pregnancy. Eur J Obstet Gynecol Reprod Biol. 2010;148(1):27–30.
  • So J, Young E, Crnosija N, et al. The utility of clinical findings to predict laboratory values in hypertensive disorders of pregnancy. J Perinat Med. 2016;44(3):277–281.
  • Reese JA, Peck JD, Deschamps DR, et al. Platelet counts during pregnancy. N Engl J Med. 2018;379(1):32–43.
  • Gupta M, Feinberg BB, Burwick RM. Thrombotic microangiopathies of pregnancy: Differential diagnosis. Pregnancy Hypertens. 2018;12:29–34.
  • Serin S, Avcı F, Ercan O, et al. Is neutrophil/lymphocyte ratio a useful marker to predict the severity of pre-eclampsia? Pregnancy Hypertens. 2016;6(1):22–25.
  • Hershko Klement A, Hadi E, Asali A, et al. Neutrophils to lymphocytes ratio and platelets to lymphocytes ratio in pregnancy: a population study. PLoS One. 2018;13(5):e0196706.
  • Anderson UD, Olsson MG, Kristensen KH, et al. Review: biochemical markers to predict preeclampsia. Placenta. 2012;33 (Suppl):S42–S47.
  • Han L, Liu X, Li H, et al. Blood coagulation parameters and platelet indices: changes in normal and preeclamptic pregnancies and predictive values for preeclampsia. PLoS One. 2014;9(12):e114488.
  • Pinheiro MB, Carvalho MG, Martins-Filho OA, et al. Severe preeclampsia: are hemostatic and inflammatory parameters associated? Clin Chim Acta. 2014;427:65–70.
  • AlSheeha MA, Alaboudi RS, Alghasham MA, et al. Platelet count and platelet indices in women with preeclampsia. VHRM. 2016;12:477–480.
  • Reese JA, Peck JD, McIntosh JJ, et al. Platelet counts in women with normal pregnancies: a systematic review. Am J Hematol. 2017;92(11):1224–1232.
  • Gogoi P, Sinha P, Gupta B, et al. Neutrophil-to-lymphocyte ratio and platelet indices in pre-eclampsia. Int J Gynaecol Obstet. 2019;144(1):16–20.
  • Canzoneri BJ, Lewis DF, Groome L, et al. Increased neutrophil numbers account for leukocytosis in women with preeclampsia. Amer J Perinatol. 2009;26(10):729–732.
  • Oylumlu M, Ozler A, Yildiz A, et al. New inflammatory markers in pre-eclampsia: echocardiographic epicardial fat thickness and neutrophil to lymphocyte ratio. Clin Exp Hypertens. 2014;36(7):503–507.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.