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Expert Review of Cardiovascular Therapy Volume 15, 2017 - Issue 5
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Original Research

The burden of familial chylomicronemia syndrome: interim results from the IN-FOCUS study

Michael DavidsonDepartment of Medicine, University of Chicago, Chicago, IL, USAView further author information
,
Michael StevensonAkcea Therapeutics, Cambridge, MA, USACorrespondence[email protected]
View further author information
,
Andrew HsiehAkcea Therapeutics, Cambridge, MA, USAView further author information
,
Zahid AhmadDivision of Nutrition and Metabolic Disease, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USAView further author information
,
Caroline CrowsonTrinity Partners, Waltham, MA, USAView further author information
&
Joseph L WitztumDepartment of Medicine, Division of Endocrinology and Metabolism, University of California San Diego, La Jolla, CA, USAView further author information
Pages 415-423 | Received 07 Mar 2017, Accepted 23 Mar 2017, Published online: 04 Apr 2017

References

  • Brahm AJ, Hegele RA. Chylomicronaemia--current diagnosis and future therapies. Nat Rev Endocrinol. 2015;11(6):352–362.
  • Symersky T, Van Hoorn B, Masclee AA. The outcome of a long-term follow-up of pancreatic function after recovery from acute pancreatitis. J Pancreas. 2006;7(4):447–453.
  • Ahmad Z, Halter R, Stevenson M. Building a better understanding of the burden of disease in familial chylomicronemia syndrome. Expert Rev Clin Pharmacol. 2017;10(1):1–3.
  • Stroes E, Moulin P, Parhofer KG, et al. Diagnostic algorithm for familial chylomicronemia syndrome. Atheroscler Supp. 2016;23:1–7.
  • Brunzell J. Familial lipoprotein lipase deficiency. In: Pagon RA, editor. Gene reviews- NCBI bookshelf. Seattle (WA): University of Washington, Seattle; 1993–2017.
  • Gaudet D, Blom D, Bruckert E, et al. Acute pancreatitis is highly prevalent and complications can be fatal in patients with familial chylomicronemia: results from a survey of lipidologists. J Clin Lipidol. 2016;10(3):680–681.
  • Nordestgaard B. Triglyceride-rich lipoproteins and atherosclerotic cardiovascular disease: new insights from epidemiology, genetics, and biology. Circ Res. 2016;118:547–563.
  • Véniant MM, Beigneux AP, Bensadoun A, et al. Lipoprotein size and susceptibility to atherosclerosis- insights from genetically modified mouse models. Curr Drug Targets. 2008;9(3):174–189.
  • Valdivielso P, Ramírez-Bueno A, Ewald N. Current knowledge of hypertriglyceridemic pancreatitis. Eur J Intern Med. 2014;25(8):689–694.
  • Češka R, Štulc T, Votavová L, et al. [Hyperlipoproteinemia and dyslipidemia as rare diseases. Diagnostics and treatment]. Vnitr Lek. 2016 Fall;62(11):887–894.
  • Hays RD. The Medical Outcomes Study (MOS) measures of patient adherence. 1994 [cited 2016 Mar 15]. Available from: http://www.rand.org/health/surveys/MOS.adherence.measures.pdf.
  • Wassef WY, Bova CA, Barton BA, et al. Pancreatitis quality of life instrument: development of a new instrument. SAGE Open Med. 2014;2:2050312114520856.
  • Engel PA, Bagal S, Broback M, et al. Physician and patient perceptions regarding physician training in rare diseases: the need for stronger educational initiatives for physicians. Orphanet J Rare Dis. 2013;1(2):1–15.
  • Brown A, Gaudet D, Gelrud A, et al. The burden and psychosocial consequences of living with familial chylomicronemia syndrome: patient and caregiver perspective. Poster session presented at: American Society of Preventive Cardiology; 2016 Sep 16–18; Boca Raton, FL.
  • Amann ST, Yadav D, Barmada MM, et al. Physical and mental quality of life in chronic pancreatitis: a case-control study from the North American Pancreatitis Study 2 cohort. Pancreas. 2013;42(2):293–300.
  • bls.gov [Internet]. Washington (DC): United States Department of Labor; [cited 2017 Feb 15]. Available from: https://www.bls.gov/bls/employment.htm.
  • Mitchell RJ, Bates P. Measuring health-related productivity loss. Popul Health Manag. 2011;14(2):93–98.
  • Doyle C, Kavanagh P, Metclafe O, et al. Health impacts of employment: a review. Dublin (Ireland): The Institute of Public Health in Ireland; 2005.

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