Focal activation patterns: breaking new grounds in the pathophysiology of atrial fibrillation

References

• Nishida K, Datino T, Macle L, et al. Atrial fibrillation ablation: translating basic mechanistic insights to the patient. J Am Coll Cardiol. 2014 Aug 26;64(8):823–831. PubMed PMID: 25145528.
   PubMed Web of Science ®Google Scholar
• van Marion DM, Lanters EA, Wiersma M, et al. Diagnosis and therapy of atrial fibrillation: the past, the present and the future. J Atr Fibrillation. 2015 Aug–Sep;8(2):1216. PubMed PMID: 27957185.
   PubMedGoogle Scholar
• Baykaner T, Zaman JAB, Wang PJ, et al. Ablation of atrial fibrillation drivers. Arrhythm Electrophysiol Rev. 2017 Dec;6(4):195–201. PubMed PMID: 29326835.
   PubMed Web of Science ®Google Scholar
• Kik C, Mouws E, Bogers A, et al. Intra-operative mapping of the atria: the first step towards individualization of atrial fibrillation therapy? Expert Rev Cardiovasc Ther. 2017 Jul;15(7):537–545. PubMed PMID: 28591518.
   PubMed Web of Science ®Google Scholar
• Haissaguerre M, Jais P, Shah DC, et al. Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins. N Engl J Med. 1998 Sep 3;339(10):659–666. PubMed PMID: 9725923.
   PubMed Web of Science ®Google Scholar
• Sahadevan J, Ryu K, Peltz L, et al. Epicardial mapping of chronic atrial fibrillation in patients: preliminary observations. Circulation. 2004 Nov 23;110(21):3293–3299. PubMed PMID: 15520305.
   PubMed Web of Science ®Google Scholar
• Nademanee K, McKenzie J, Kosar E, et al. A new approach for catheter ablation of atrial fibrillation: mapping of the electrophysiologic substrate. J Am Coll Cardiol. 2004 Jun 2;43(11):2044–2053. PubMed PMID: 15172410.
   PubMed Web of Science ®Google Scholar
• Konings KT, Kirchhof CJ, Smeets JR, et al. High-density mapping of electrically induced atrial fibrillation in humans. Circulation. 1994 Apr;89(4):1665–1680. PubMed PMID: 8149534.
   PubMed Web of Science ®Google Scholar
• Mouws E, Lanters EAH, Teuwen CP, et al. Epicardial breakthrough waves during sinus rhythm: depiction of the arrhythmogenic substrate? Circ Arrhythm Electrophysiol. 2017 Sep;10(9):e005145. PubMed PMID: 28912205.
   Web of Science ®Google Scholar
• Nitta T, Ohmori H, Sakamoto S, et al. Map-guided surgery for atrial fibrillation. J Thorac Cardiovasc Surg. 2005 Feb;129(2):291–299. PubMed PMID: 15678038.
   PubMed Web of Science ®Google Scholar
• Narayan SM, Krummen DE, Enyeart MW, et al. Computational mapping identifies localized mechanisms for ablation of atrial fibrillation. PLoS One. 2012;7(9):e46034. PubMed PMID: 23049929.
   PubMed Web of Science ®Google Scholar
• Narayan SM, Shivkumar K, Krummen DE, et al. Panoramic electrophysiological mapping but not electrogram morphology identifies stable sources for human atrial fibrillation: stable atrial fibrillation rotors and focal sources relate poorly to fractionated electrograms. Circ Arrhythm Electrophysiol. 2013 Feb;6(1):58–67. PubMed PMID: 23392583.
   PubMed Web of Science ®Google Scholar
• Shivkumar K, Ellenbogen KA, Hummel JD, et al. Acute termination of human atrial fibrillation by identification and catheter ablation of localized rotors and sources: first multicenter experience of focal impulse and rotor modulation (FIRM) ablation. J Cardiovasc Electrophysiol. 2012 Dec;23(12):1277–1285. PubMed PMID: 23130890.
   PubMed Web of Science ®Google Scholar
• Jones AR, Krummen DE, Narayan SM. Non-invasive identification of stable rotors and focal sources for human atrial fibrillation: mechanistic classification of atrial fibrillation from the electrocardiogram. Europace. 2013 Sep;15(9):1249–1258. PubMed PMID: 23449925.
   PubMed Web of Science ®Google Scholar
• Lee G, Kumar S, Teh A, et al. Epicardial wave mapping in human long-lasting persistent atrial fibrillation: transient rotational circuits, complex wavefronts, and disorganized activity. Eur Heart J. 2014 Jan;35(2):86–97. PubMed PMID: 23935092.
   PubMed Web of Science ®Google Scholar
• Lee G, McLellan AJ, Hunter RJ, et al. Panoramic characterization of endocardial left atrial activation during human persistent AF: insights from non-contact mapping. Int J Cardiol. 2017 Feb;1(228):406–411. PubMed PMID: 27870970.
   Web of Science ®Google Scholar
• Harada A, Sasaki K, Fukushima T, et al. Atrial activation during chronic atrial fibrillation in patients with isolated mitral valve disease. Ann Thorac Surg. 1996 Jan;61(1):104–111. discussion 111-2. PubMed PMID: 8561533.
   PubMed Web of Science ®Google Scholar
• Holm M, Johansson R, Brandt J, et al. Epicardial right atrial free wall mapping in chronic atrial fibrillation. Documentation of repetitive activation with a focal spread–a hitherto unrecognised phenomenon in man. Eur Heart J. 1997 Feb;18(2):290–310. PubMed PMID: 9043847.
   PubMed Web of Science ®Google Scholar
• Nitta T, Ishii Y, Miyagi Y, et al. Concurrent multiple left atrial focal activations with fibrillatory conduction and right atrial focal or reentrant activation as the mechanism in atrial fibrillation. J Thorac Cardiovasc Surg. 2004 Mar;127(3):770–778. PubMed PMID: 15001906.
   PubMed Web of Science ®Google Scholar
• de Groot NM, Houben RP, Smeets JL, et al. Electropathological substrate of longstanding persistent atrial fibrillation in patients with structural heart disease: epicardial breakthrough. Circulation. 2010 Oct 26;122(17):1674–1682. PubMed PMID: 20937979.
   PubMed Web of Science ®Google Scholar
• Lee S, Sahadevan J, Khrestian CM, et al. Simultaneous biatrial high-density (510-512 electrodes) epicardial mapping of persistent and long-standing persistent atrial fibrillation in patients: new insights into the mechanism of its maintenance. Circulation. 2015 Dec 1;132(22):2108–2117. PubMed PMID: 26499963.
   PubMed Web of Science ®Google Scholar
• Schricker AA, Lalani GG, Krummen DE, et al. Human atrial fibrillation initiates via organized rather than disorganized mechanisms. Circ Arrhythm Electrophysiol. 2014 Oct;7(5):816–824. PubMed PMID: 25217042.
   PubMed Web of Science ®Google Scholar
• Tan AY, Chou CC, Zhou S, et al. Electrical connections between left superior pulmonary vein, left atrium, and ligament of Marshall: implications for mechanisms of atrial fibrillation. Am J Physiol Heart Circ Physiol. 2006 Jan;290(1):H312–H322. PubMed PMID: 16155107.
   PubMed Web of Science ®Google Scholar
• Lee S, Sahadevan J, Khrestian CM, et al. High density mapping of atrial fibrillation during vagal nerve stimulation in the canine heart: restudying the Moe hypothesis. J Cardiovasc Electrophysiol. 2013 Mar;24(3):328–335. PubMed PMID: 23210508.
   PubMed Web of Science ®Google Scholar
• Kuklik P, Lau DH, Ganesan AN, et al. High-density mapping of atrial fibrillation in a chronic substrate: evidence for distinct modes of repetitive wavefront propagation. Int J Cardiol. 2015 Nov;15(199):407–414. PubMed PMID: 26253050.
   Web of Science ®Google Scholar
• Verheule S, Tuyls E, van Hunnik A, et al. Fibrillatory conduction in the atrial free walls of goats in persistent and permanent atrial fibrillation. Circ Arrhythm Electrophysiol. 2010 Dec;3(6):590–599. PubMed PMID: 20937721.
   PubMed Web of Science ®Google Scholar
• Eckstein J, Zeemering S, Linz D, et al. Transmural conduction is the predominant mechanism of breakthrough during atrial fibrillation: evidence from simultaneous endo-epicardial high-density activation mapping. Circ Arrhythm Electrophysiol. 2013 Apr;6(2):334–341. PubMed PMID: 23512204.
   PubMed Web of Science ®Google Scholar
• Hirose M, Carlson MD, Laurita KR. Cellular mechanisms of vagally mediated atrial tachyarrhythmia in isolated arterially perfused canine right atria. J Cardiovasc Electrophysiol. 2002 Sep;13(9):918–926. PubMed PMID: 12380933.
   PubMed Web of Science ®Google Scholar
• Okuyama Y, Miyauchi Y, Park AM, et al. High resolution mapping of the pulmonary vein and the vein of Marshall during induced atrial fibrillation and atrial tachycardia in a canine model of pacing-induced congestive heart failure. J Am Coll Cardiol. 2003 Jul 16;42(2):348–360. PubMed PMID: 12875775.
   PubMed Web of Science ®Google Scholar
• Zheng X, Huang J, Walcott GP, et al. Activation sequences following failed atrial defibrillation. Heart Rhythm. 2004 Nov;1(5):616–623. PubMed PMID: 15851229.
   PubMed Web of Science ®Google Scholar
• Arentz T, Haegeli L, Sanders P, et al. High-density mapping of spontaneous pulmonary vein activity initiating atrial fibrillation in humans. J Cardiovasc Electrophysiol. 2007 Jan;18(1):31–38. PubMed PMID: 17229297.
   PubMed Web of Science ®Google Scholar
• Yamabe H, Morihisa K, Tanaka Y, et al. Mechanisms of the maintenance of atrial fibrillation: role of the complex fractionated atrial electrogram assessed by noncontact mapping. Heart Rhythm. 2009 Aug;6(8):1120–1128. PubMed PMID: 19539538.
   PubMed Web of Science ®Google Scholar
• Narayan SM, Krummen DE, Rappel WJ. Clinical mapping approach to diagnose electrical rotors and focal impulse sources for human atrial fibrillation. J Cardiovasc Electrophysiol. 2012 May;23(5):447–454. PubMed PMID: 22537106.
   PubMed Web of Science ®Google Scholar
• Kumagai K, Yasuda T, Tojo H, et al. Role of rapid focal activation in the maintenance of atrial fibrillation originating from the pulmonary veins. Pacing Clin Electrophysiol. 2000 Nov;23(11 Pt 2):1823–1827. PubMed PMID: 11139934.
   PubMed Web of Science ®Google Scholar
• Schilling RJ, Kadish AH, Peters NS, et al. Endocardial mapping of atrial fibrillation in the human right atrium using a non-contact catheter. Eur Heart J. 2000 Apr;21(7):550–564. PubMed PMID: 10775010.
   PubMed Web of Science ®Google Scholar
• Takahashi Y, Hocini M, O’Neill MD, et al. Sites of focal atrial activity characterized by endocardial mapping during atrial fibrillation. J Am Coll Cardiol. 2006 May 16;47(10):2005–2012. PubMed PMID: 16697317.
   PubMed Web of Science ®Google Scholar
• Takahashi Y, Iwai S, Yamashita S, et al. Novel mapping technique for localization of focal and reentrant activation during atrial fibrillation. J Cardiovasc Electrophysiol. 2017 Apr;28(4):375–382. PubMed PMID: 28063269.
   PubMed Web of Science ®Google Scholar
• Kumagai K, Khrestian C, Waldo AL. Simultaneous multisite mapping studies during induced atrial fibrillation in the sterile pericarditis model. Insights into the mechanism of its maintenance. Circulation. 1997 Jan 21;95(2):511–521. PubMed PMID: 9008471.
   PubMed Web of Science ®Google Scholar
• Derakhchan K, Li D, Courtemanche M, et al. Method for simultaneous epicardial and endocardial mapping of in vivo canine heart: application to atrial conduction properties and arrhythmia mechanisms. J Cardiovasc Electrophysiol. 2001 May;12(5):548–555. PubMed PMID: 11386516.
   PubMed Web of Science ®Google Scholar
• Teuwen CP, Yaksh A, Lanters EA, et al. Relevance of conduction disorders in Bachmann’s bundle during sinus rhythm in humans. Circ Arrhythm Electrophysiol. 2016 May;9(5):e003972. PubMed PMID: 27153879.
   PubMed Web of Science ®Google Scholar
• Lemery R, Guiraudon G, Veinot JP. Anatomic description of Bachmann’s bundle and its relation to the atrial septum. Am J Cardiol. 2003 Jun 15;91(12):1482–5, A8. PubMed PMID: 12804741.
   PubMed Web of Science ®Google Scholar
• Platonov PG, Mitrofanova L, Ivanov V, et al. Substrates for intra-atrial and interatrial conduction in the atrial septum: anatomical study on 84 human hearts. Heart Rhythm. 2008 Aug;5(8):1189–1195. PubMed PMID: 18675231.
   PubMed Web of Science ®Google Scholar
• Schuessler RB, Kawamoto T, Hand DE, et al. Simultaneous epicardial and endocardial activation sequence mapping in the isolated canine right atrium. Circulation. 1993 Jul;88(1):250–263. PubMed PMID: 8319340.
   PubMed Web of Science ®Google Scholar
• Everett T, Wilson EE, Hulley GS, et al. Transmural characteristics of atrial fibrillation in canine models of structural and electrical atrial remodeling assessed by simultaneous epicardial and endocardial mapping. Heart Rhythm. 2010 Apr;7(4):506–517. PubMed PMID: 20184976.
   PubMed Web of Science ®Google Scholar
• Yamazaki M, Mironov S, Taravant C, et al. Heterogeneous atrial wall thickness and stretch promote scroll waves anchoring during atrial fibrillation. Cardiovasc Res. 2012 Apr 1;94(1):48–57. PubMed PMID: 22227155.
   PubMed Web of Science ®Google Scholar
• de Groot N, van der Does L, Yaksh A, et al. Direct proof of endo-epicardial asynchrony of the atrial wall during atrial fibrillation in humans. Circ Arrhythm Electrophysiol. 2016 May;9(5):e003648. PubMed PMID: 27103089.
   Web of Science ®Google Scholar
• Gray RA, Pertsov AM, Jalife J. Incomplete reentry and epicardial breakthrough patterns during atrial fibrillation in the sheep heart. Circulation. 1996 Nov 15;94(10):2649–2661. PubMed PMID: 8921813.
   PubMed Web of Science ®Google Scholar
• Skanes AC, Mandapati R, Berenfeld O, et al. Spatiotemporal periodicity during atrial fibrillation in the isolated sheep heart. Circulation. 1998 Sep 22;98(12):1236–1248. PubMed PMID: 9743516.
   PubMed Web of Science ®Google Scholar
• Chen SA, Chen YJ, Yeh HI, et al. Pathophysiology of the pulmonary vein as an atrial fibrillation initiator. Pacing Clin Electrophysiol. 2003 Jul;26(7 Pt 2):1576–1582. PubMed PMID: 12914606.
   PubMed Web of Science ®Google Scholar
• Patterson E, Jackman WM, Beckman KJ, et al. Spontaneous pulmonary vein firing in man: relationship to tachycardia-pause early afterdepolarizations and triggered arrhythmia in canine pulmonary veins in vitro. J Cardiovasc Electrophysiol. 2007 Sep;18(10):1067–1075. PubMed PMID: 17655663.
   PubMed Web of Science ®Google Scholar
• van der Does L. Unipolar atrial electrogram morphology from an epicardial and endocardial perspective. Heart Rhythm. 2018;15:879–887.
   PubMed Web of Science ®Google Scholar
• Allessie MA, de Groot NM, Houben RP, et al. Electropathological substrate of long-standing persistent atrial fibrillation in patients with structural heart disease: longitudinal dissociation. Circ Arrhythm Electrophysiol. 2010 Dec;3(6):606–615. PubMed PMID: 20719881.
   PubMed Web of Science ®Google Scholar
• Henning RH, Brundel B. Proteostasis in cardiac health and disease. Nat Rev Cardiol. 2017 Nov;14(11):637–653. PubMed PMID: 28660894.
   PubMed Web of Science ®Google Scholar