Endothelial function in obesity and effects of bariatric and metabolic surgery

References

• Sanches E, Timmermans M, Topal B, et al. Cardiac remodeling in obesity and after bariatric and metabolic surgery; is there a role for gastro-intestinal hormones? Expert Rev Cardiovasc Ther. 2019 Nov;17(11):771–790
   PubMed Web of Science ®Google Scholar
• Ng M, Fleming T, Robinson M, et al. Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: a systematic analysis for the global burden of disease study 2013. Lancet. 2014 Aug 30;384(9945):766–781.
   PubMed Web of Science ®Google Scholar
• Sjostrom L, Narbro K, Sjostrom CD, et al. Effects of bariatric surgery on mortality in Swedish obese subjects. N Engl J Med. 2007 Aug 23;357(8):741–752.
   PubMed Web of Science ®Google Scholar
• Appachi S, Kelly KR, Schauer PR, et al. Reduced cardiovascular risk following bariatric surgeries is related to a partial recovery from “adiposopathy”. Obes Surg. 2011 Dec;21(12):1928–1936.
   PubMed Web of Science ®Google Scholar
• Appachi S, Kashyap SR. ‘Adiposopathy’ and cardiovascular disease: the benefits of bariatric surgery. Curr Opin Cardiol. 2013 Sep;28(5):540–546.
   PubMed Web of Science ®Google Scholar
• Lupoli R, Di Minno MN, Guidone C, et al. Effects of bariatric surgery on markers of subclinical atherosclerosis and endothelial function: a meta-analysis of literature studies. Int J Obes (Lond). 2016 Mar;40(3):395–402.
   PubMed Web of Science ®Google Scholar
• Toth PP, Danese M, Villa G, et al. Estimated burden of cardiovascular disease and value-based price range for evolocumab in a high-risk, secondary-prevention population in the US payer context. J Med Econ. 2017 Jun;20(6):555–564.
   PubMed Web of Science ®Google Scholar
• Achari AE, Jain SK. l-Cysteine supplementation increases insulin sensitivity mediated by upregulation of GSH and adiponectin in high glucose treated 3T3-L1 adipocytes. Arch Biochem Biophys. 2017 Sep 15;630:54–65.
   PubMed Web of Science ®Google Scholar
• Achari AE, Jain SK. L-Cysteine supplementation increases adiponectin synthesis and secretion, and GLUT4 and glucose utilization by upregulating disulfide bond A-like protein expression mediated by MCP-1 inhibition in 3T3-L1 adipocytes exposed to high glucose. Mol Cell Biochem. 2016 Mar;414(1–2):105–113.
   PubMed Web of Science ®Google Scholar
• Achari AE, Jain SK. Adiponectin, a therapeutic target for obesity, diabetes, and endothelial dysfunction. Int J Mol Sci. 2017. 21. 18(6):Jun.
   Web of Science ®Google Scholar
• Cummings DE, Cohen RV, Beyond BMI. the need for new guidelines governing the use of bariatric and metabolic surgery. Lancet Diabetes Endocrinol. 2014 2;Feb(2):175–181.
   Google Scholar
• Ouwens DM, Sell H, Greulich S, et al. The role of epicardial and perivascular adipose tissue in the pathophysiology of cardiovascular disease. J Cell Mol Med. 2010 Sep;14(9):2223–2234.
   PubMed Web of Science ®Google Scholar
• Farb MG, Ganley-Leal L, Mott M, et al. Arteriolar function in visceral adipose tissue is impaired in human obesity. Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):467–473.
   PubMed Web of Science ®Google Scholar
• Endemann DH, Schiffrin EL. Endothelial dysfunction. J Am Soc Nephrol. 2004 Aug;15(8):1983–1992.
   PubMed Web of Science ®Google Scholar
• Flammer AJ, Anderson T, Celermajer DS, et al. The assessment of endothelial function: from research into clinical practice. Circulation. 2012 Aug 7;126(6):753–767.
   PubMed Web of Science ®Google Scholar
• Sahakyan KR, Somers VK, Rodriguez-Escudero JP, et al. Normal-weight central obesity: implications for total and cardiovascular mortality. Ann Intern Med. 2015 Dec 1;163(11):827–835.
   PubMed Web of Science ®Google Scholar
• Capehorn MS, Haslam DW, Welbourn R. Obesity treatment in the UK health system. Curr Obes Rep. 2016 Sep;5(3):320–326.
   PubMed Web of Science ®Google Scholar
• Chistiakov DA, Revin VV, Sobenin IA, et al. Vascular endothelium: functioning in norm, changes in atherosclerosis and current dietary approaches to improve endothelial function. Mini Rev Med Chem. 2015;15(4):338–350.
   PubMed Web of Science ®Google Scholar
• Minami T, Aird WC. Endothelial cell gene regulation. Trends Cardiovasc Med. 2005 Jul;15(5):174–184.
   PubMed Web of Science ®Google Scholar
• Muniyappa R, Sowers JR. Role of insulin resistance in endothelial dysfunction. Rev Endocr Metab Disord. 2013 Mar;14(1):5–12.
   PubMed Web of Science ®Google Scholar
• Furchgott RF, Zawadzki JV. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature. 1980 Nov 27;288(5789):373–376.
   PubMed Web of Science ®Google Scholar
• Ignarro LJ, Buga GM, Wood KS, et al. Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proc Natl Acad Sci U S A. 1987 Dec;84(24):9265–9269.
   PubMed Web of Science ®Google Scholar
• Nafisa A, Gray SG, Cao Y, et al. Endothelial function and dysfunction: impact of metformin. Pharmacol Ther. 2018 Dec;192:150–162.
   PubMed Web of Science ®Google Scholar
• Green DJ, Hopman MT, Padilla J, et al. Vascular adaptation to exercise in humans: role of hemodynamic stimuli. Physiol Rev. 2017 Apr;97(2):495–528.
   PubMed Web of Science ®Google Scholar
• Green DJ, Jones H, Thijssen D, et al. Flow-mediated dilation and cardiovascular event prediction: does nitric oxide matter? Hypertens. 2011 Mar;57(3):363–369.
   PubMed Web of Science ®Google Scholar
• Just A, Whitten CL, Arendshorst WJ. Reactive oxygen species participate in acute renal vasoconstrictor responses induced by ETA and ETB receptors. Am J Physiol Renal Physiol. 2008 Apr;294(4):F719–28.
   PubMed Web of Science ®Google Scholar
• Lai WK, Kan MY. Homocysteine-induced endothelial dysfunction. Ann Nutr Metab. 2015;67(1):1–12.
   PubMed Web of Science ®Google Scholar
• Moncada S, Gryglewski R, Bunting S, et al. An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation. Nature. 1976 Oct 21;263(5579):663–665.
   PubMed Web of Science ®Google Scholar
• Palmer RM, Ferrige AG, Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature. 1987 Jun 11-17;327(6122):524–526.
   PubMed Web of Science ®Google Scholar
• Yanagisawa M, Kurihara H, Kimura S, et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature. 1988 Mar 31;332(6163):411–415.
   PubMed Web of Science ®Google Scholar
• Barton M, Haudenschild CC. Endothelium and atherogenesis: endothelial therapy revisited. J Cardiovasc Pharmacol. 2001 Nov;38(Suppl 2):S23–5.
   PubMedGoogle Scholar
• Feletou M, Vanhoutte PM. Endothelial dysfunction: a multifaceted disorder (The Wiggers Award Lecture). Am J Physiol Heart Circ Physiol. 2006 Sep;291(3):H985–1002.
   PubMed Web of Science ®Google Scholar
• Brainin P, Frestad D, Prescott E. The prognostic value of coronary endothelial and microvascular dysfunction in subjects with normal or non-obstructive coronary artery disease: A systematic review and meta-analysis. Int J Cardiol. 2018 Mar;1(254):1–9.
   Google Scholar
• Ghosh A, Gao L, Thakur A, et al. Role of free fatty acids in endothelial dysfunction. J Biomed Sci. 2017 Jul 27;24(1):50.
   PubMed Web of Science ®Google Scholar
• Sena CM, Pereira AM, Seica R. Endothelial dysfunction - a major mediator of diabetic vascular disease. Biochim Biophys Acta. 2013 Dec;1832(12):2216–2231.
   PubMed Web of Science ®Google Scholar
• Versari D, Daghini E, Virdis A, et al. Endothelial dysfunction as a target for prevention of cardiovascular disease. Diabetes Care. 2009 Nov;32(Suppl 2):S314–21.
   PubMed Web of Science ®Google Scholar
• Bakker W, Eringa EC, Sipkema P, et al. Endothelial dysfunction and diabetes: roles of hyperglycemia, impaired insulin signaling and obesity. Cell Tissue Res. 2009 Jan;335(1):165–189.
   PubMed Web of Science ®Google Scholar
• Kim JA, Montagnani M, Koh KK, et al. Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms. Circulation. 2006 Apr 18;113(15):1888–1904.
   PubMed Web of Science ®Google Scholar
• Nigro J, Osman N, Dart AM, et al. Insulin resistance and atherosclerosis. Endocr Rev. 2006 May;27(3):242–259.
   PubMed Web of Science ®Google Scholar
• Pautasso E, Koretzky M, Marcon L, et al. Can the cold pressor test predict future cardiovascular events in patients without demonstrated ischemic heart disease by SPECT? Int J Cardiol. 2014 Aug 1;175(2):226–232.
   PubMed Web of Science ®Google Scholar
• Vane JR, Anggard EE, Botting RM. Regulatory functions of the vascular endothelium. N Engl J Med. 1990 Jul 5;323(1):27–36.
   PubMed Web of Science ®Google Scholar
• Fuster V, Badimon L, Badimon JJ, et al. The pathogenesis of coronary artery disease and the acute coronary syndromes (2). N Engl J Med. 1992 Jan 30;326(5):310–318.
   PubMed Web of Science ®Google Scholar
• Liu Z, Wei F, Zhao Y, et al. Day-by-day variability of self-measured blood pressure at home associated with cold pressor test norepinephrine, and heart rate variability in normotensive to moderate hypertensive. Int J Cardiol. 2013 Oct 9;168(4):4574–4576.
   PubMed Web of Science ®Google Scholar
• Antonopoulos AS, Tousoulis D, Antoniades C, et al. Genetic variability on adiponectin gene affects myocardial infarction risk: the role of endothelial dysfunction. Int J Cardiol. 2013 Sep 20;168(1):326–330.
   PubMed Web of Science ®Google Scholar
• Drexler H. Endothelial dysfunction: clinical implications. Prog Cardiovasc Dis. 1997 Jan-Feb;39(4):287–324.
   PubMed Web of Science ®Google Scholar
• Griendling KK, Ushio-Fukai M. NADH/NADPH oxidase and vascular function. Trends Cardiovasc Med. 1997 Nov;7(8):301–307.
   PubMed Web of Science ®Google Scholar
• Nabel EG, Ganz P, Gordon JB, et al. Dilation of normal and constriction of atherosclerotic coronary arteries caused by the cold pressor test. Circulation. 1988 Jan;77(1):43–52.
   PubMed Web of Science ®Google Scholar
• Schachinger V, Britten MB, Zeiher AM. Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease. Circulation. 2000 Apr 25;101(16):1899–1906.
   PubMed Web of Science ®Google Scholar
• Thijssen DH, Black MA, Pyke KE, et al. Assessment of flow-mediated dilation in humans: a methodological and physiological guideline. Am J Physiol Heart Circ Physiol. 2011 Jan;300(1):H2–12.
   PubMed Web of Science ®Google Scholar
• Anderson TJ, Uehata A, Gerhard MD, et al. Close relation of endothelial function in the human coronary and peripheral circulations. J Am Coll Cardiol. 1995 Nov 1;26(5):1235–1241.
   PubMed Web of Science ®Google Scholar
• Matsuzawa Y, Guddeti RR, Kwon TG, et al. Treating coronary disease and the impact of endothelial dysfunction. Prog Cardiovasc Dis. 2015 Mar-Apr;57(5):431–442.
   PubMed Web of Science ®Google Scholar
• Matsuzawa Y, Sugiyama S, Sumida H, et al. Peripheral endothelial function and cardiovascular events in high-risk patients. J Am Heart Assoc. 2013 Nov 25;2(6):e000426.
   PubMed Web of Science ®Google Scholar
• Kuvin JT, Patel AR, Sliney KA, et al. Assessment of peripheral vascular endothelial function with finger arterial pulse wave amplitude. Am Heart J. 2003 Jul;146(1):168–174.
   PubMed Web of Science ®Google Scholar
• Bonetti PO, Pumper GM, Higano ST, et al. Noninvasive identification of patients with early coronary atherosclerosis by assessment of digital reactive hyperemia. J Am Coll Cardiol. 2004 Dec 7;44(11):2137–2141.
   PubMed Web of Science ®Google Scholar
• Lerman A, Zeiher AM. Endothelial function: cardiac events. Circulation. 2005 Jan 25;111(3):363–368.
   PubMed Web of Science ®Google Scholar
• Little WC, Downes TR, Applegate RJ. The underlying coronary lesion in myocardial infarction: implications for coronary angiography. Clin Cardiol. 1991 Nov;14(11):868–874.
   PubMed Web of Science ®Google Scholar
• Yeboah J, Folsom AR, Burke GL, et al. Predictive value of brachial flow-mediated dilation for incident cardiovascular events in a population-based study: the multi-ethnic study of atherosclerosis. Circulation. 2009 Aug 11;120(6):502–509.
   PubMed Web of Science ®Google Scholar
• Yeboah J, Crouse JR, Hsu FC, et al. Brachial flow-mediated dilation predicts incident cardiovascular events in older adults: the Cardiovascular Health Study. Circulation. 2007 May 8;115(18):2390–2397.
   PubMed Web of Science ®Google Scholar
• Inaba Y, Chen JA, Bergmann SR. Prediction of future cardiovascular outcomes by flow-mediated vasodilatation of brachial artery: a meta-analysis. Int J Cardiovasc Imaging. 2010 Aug;26(6):631–640.
   PubMed Web of Science ®Google Scholar
• Ras RT, Streppel MT, Draijer R, et al. Flow-mediated dilation and cardiovascular risk prediction: a systematic review with meta-analysis. Int J Cardiol. 2013 Sep 20;168(1):344–351.
   PubMed Web of Science ®Google Scholar
• Xu Y, Arora RC, Hiebert BM, et al. Non-invasive endothelial function testing and the risk of adverse outcomes: a systematic review and meta-analysis. Eur Heart J Cardiovasc Imaging. 2014 Jul;15(7):736–746.
   PubMed Web of Science ®Google Scholar
• Furchgott RF. The role of endothelium in the responses of vascular smooth muscle to drugs. Annu Rev Pharmacol Toxicol. 1984;24(1):175–197.
   PubMedGoogle Scholar
• Furchgott RF. Role of endothelium in responses of vascular smooth muscle. Circ Res. 1983 Nov;53(5):557–573.
   PubMed Web of Science ®Google Scholar
• Robinson AT, Fancher IS, Mahmoud AM, et al. Microvascular vasodilator plasticity after acute exercise. Exerc Sport Sci Rev. 2018 Jan;46(1):48–55.
   PubMed Web of Science ®Google Scholar
• Lloyd-Jones DM, Bloch KD. The vascular biology of nitric oxide and its role in atherogenesis. Annu Rev Med. 1996;47(1):365–375.
   PubMedGoogle Scholar
• Vanhoutte PM, Zhao Y, Xu A, et al. Thirty Years of saying NO: sources, fate, actions, and misfortunes of the endothelium-derived vasodilator mediator. Circ Res. 2016 Jul 8;119(2):375–396.
   PubMed Web of Science ®Google Scholar
• Muniyappa R, Quon MJ. Insulin action and insulin resistance in vascular endothelium. Curr Opin Clin Nutr Metab Care. 2007 Jul;10(4):523–530.
   PubMed Web of Science ®Google Scholar
• Mather KJ, Steinberg HO, Baron AD. Insulin resistance in the vasculature. J Clin Invest. 2013 Mar;123(3):1003–1004.
   PubMed Web of Science ®Google Scholar
• Kuboki K, Jiang ZY, Takahara N, et al. Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo: a specific vascular action of insulin. Circulation. 2000 Feb 15;101(6):676–681.
   PubMed Web of Science ®Google Scholar
• Zhang DX, Borbouse L, Gebremedhin D, et al. H2O2-induced dilation in human coronary arterioles: role of protein kinase G dimerization and large-conductance Ca2+-activated K+ channel activation. Circ Res. 2012 Feb 3;110(3):471–480.
   PubMed Web of Science ®Google Scholar
• Kalupahana NS, Massiera F, Quignard-Boulange A, et al. Overproduction of angiotensinogen from adipose tissue induces adipose inflammation, glucose intolerance, and insulin resistance. Obesity (Silver Spring, Md). 2012 Jan;20(1):48–56.
   PubMed Web of Science ®Google Scholar
• Kwaifa IK, Bahari H, Yong YK, et al. Endothelial dysfunction in obesity-induced inflammation: molecular mechanisms and clinical implications. Biomolecules. 2020 13; 10(2):Feb.
   Web of Science ®Google Scholar
• Roberts AC, Porter KE. Cellular and molecular mechanisms of endothelial dysfunction in diabetes. Diab Vasc Dis Res. 2013 Nov;10(6):472–482.
   PubMed Web of Science ®Google Scholar
• Brady EM, Webb DR, Morris DH, et al. Investigating endothelial activation and oxidative stress in relation to glycaemic control in a multiethnic population. Exp Diabetes Res. 2012;2012:386041.
   PubMedGoogle Scholar
• Mussbacher M, Salzmann M, Brostjan C, et al. Cell type-specific roles of NF-kappaB linking inflammation and thrombosis. Front Immunol. 2019;10:85.
   PubMed Web of Science ®Google Scholar
• Sprague AH, Khalil RA. Inflammatory cytokines in vascular dysfunction and vascular disease. Biochem Pharmacol. 2009 Sep 15;78(6):539–552.
   PubMed Web of Science ®Google Scholar
• Reaven GM, Banting lecture 1988. Role of insulin resistance in human disease. Diabetes 1988 Dec;37(12):1595–1607.
   PubMed Web of Science ®Google Scholar
• Kotsis V, Stabouli S, Papakatsika S, et al. Mechanisms of obesity-induced hypertension. Hypertens Res. 2010 May;33(5):386–393.
   PubMed Web of Science ®Google Scholar
• De Boer MP, Meijer RI, Wijnstok NJ, et al. Microvascular dysfunction: a potential mechanism in the pathogenesis of obesity-associated insulin resistance and hypertension. Microcircu (New York, NY: 1994). 2012 Jan;19(1):5–18.
   PubMed Web of Science ®Google Scholar
• Jonk AM, Houben AJ, de Jongh RT, et al. Microvascular dysfunction in obesity: a potential mechanism in the pathogenesis of obesity-associated insulin resistance and hypertension. Physiol (Bethesda, Md). 2007 Aug;22:252–260.
   PubMed Web of Science ®Google Scholar
• El Assar M, Ruiz de Adana JC, Angulo J, et al. Preserved endothelial function in human obesity in the absence of insulin resistance. J Transl Med. 2013 Oct;20(11):263.
   Google Scholar
• Cardillo C, Campia U, Iantorno M, et al. Enhanced vascular activity of endogenous endothelin-1 in obese hypertensive patients. Hypertens. 2004 Jan;43(1):36–40.
   PubMed Web of Science ®Google Scholar
• Habib P, Scrocco JD, Terek M, et al. Effects of bariatric surgery on inflammatory, functional and structural markers of coronary atherosclerosis. Am J Cardiol. 2009 Nov 1;104(9):1251–1255.
   PubMed Web of Science ®Google Scholar
• Osto E, Doytcheva P, Corteville C, et al. Rapid and body weight-independent improvement of endothelial and high-density lipoprotein function after Roux-en-Y gastric bypass: role of glucagon-like peptide-1. Circulation. 2015 Mar 10;131(10):871–881.
   PubMed Web of Science ®Google Scholar
• Paneni F, Beckman JA, Creager MA, et al. Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: part I. Eur Heart J. 2013 Aug;34(31):2436–2443.
   PubMed Web of Science ®Google Scholar
• Al Suwaidi J, Higano ST, Holmes DR Jr., et al. Obesity is independently associated with coronary endothelial dysfunction in patients with normal or mildly diseased coronary arteries. J Am Coll Cardiol. 2001 May;37(6):1523–1528.
   PubMed Web of Science ®Google Scholar
• Ansar S, Koska J, Reaven PD. Postprandial hyperlipidemia, endothelial dysfunction and cardiovascular risk: focus on incretins. Cardiovasc Diabetol. 2011 7;Jul(10):61.
   Google Scholar
• Segovia SA, Vickers MH, Gray C, et al. Maternal obesity, inflammation, and developmental programming. Biomed Res Int. 2014;2014:418975.
   PubMed Web of Science ®Google Scholar
• Segovia SA, Vickers MH, Reynolds CM. The impact of maternal obesity on inflammatory processes and consequences for later offspring health outcomes. J Dev Orig Health Dis. 2017 Oct;8(5):529–540.
   PubMed Web of Science ®Google Scholar
• Ailhaud G, Fukamizu A, Massiera F, et al. Angiotensinogen, angiotensin II and adipose tissue development. Int J Obes Relat Metab Disord. 2000 Nov;24(Suppl 4):S33–5.
   PubMed Web of Science ®Google Scholar
• Yvan-Charvet L, Quignard-Boulange A. Role of adipose tissue renin-angiotensin system in metabolic and inflammatory diseases associated with obesity. Kidney Int. 2011 Jan;79(2):162–168.
   PubMed Web of Science ®Google Scholar
• Levi M. van der Poll T. Inflammation and coagulation. Crit Care Med. 2010 Feb;38(2 Suppl):S26–34.
   PubMed Web of Science ®Google Scholar
• Levi M, van der Poll T, Schultz M. Infection and inflammation as risk factors for thrombosis and atherosclerosis. Semin Thromb Hemost. 2012 Jul;38(5):506–514.
   PubMed Web of Science ®Google Scholar
• Margetic S. Inflammation and haemostasis. Biochem Med (Zagreb). 2012;22(1):49–62.
   PubMed Web of Science ®Google Scholar
• Vilahur G, Ben-Aicha S, Badimon L. New insights into the role of adipose tissue in thrombosis. Cardiovasc Res. 2017 Jul 1;113(9):1046–1054.
   PubMed Web of Science ®Google Scholar
• Brethauer SA, Heneghan HM, Eldar S, et al. Early effects of gastric bypass on endothelial function, inflammation, and cardiovascular risk in obese patients. Surg Endosc.2011 Aug;25(8):2650–2659.
   PubMed Web of Science ®Google Scholar
• Garcia G, Bunout D, Mella J, et al. Bariatric surgery decreases carotid intima-media thickness in obese subjects. Nutricion hospitalaria. 2013 Jul-Aug;28(4):1102–1108.
   PubMed Web of Science ®Google Scholar
• Gokce N, Vita JA, McDonnell M, et al. Effect of medical and surgical weight loss on endothelial vasomotor function in obese patients. Am J Cardiol. 2005 Jan 15;95(2):266–268.
   PubMed Web of Science ®Google Scholar
• Lind L, Zethelius B, Sundbom M, et al. Vasoreactivity is rapidly improved in obese subjects after gastric bypass surgery. Int J Obes (Lond). 2009 Dec;33(12):1390–1395.
   PubMed Web of Science ®Google Scholar
• Faria G, Preto J, da Costa EL, et al. Acute improvement in insulin resistance after laparoscopic Roux-en-Y gastric bypass: is 3 days enough to correct insulin metabolism? Obes Surg. 2013 Jan;23(1):103–110.
   PubMed Web of Science ®Google Scholar
• Nerla R, Tarzia P, Sestito A, et al. Effect of bariatric surgery on peripheral flow-mediated dilation and coronary microvascular function. Nutr Metab Cardiovasc Dis. 2012 Aug;22(8):626–634.
   PubMed Web of Science ®Google Scholar
• Saleh MH, Bertolami MC, Assef JE, et al. Improvement of atherosclerotic markers in non-diabetic patients after bariatric surgery. Obes Surg. 2012 Nov;22(11):1701–1707.
   PubMed Web of Science ®Google Scholar
• Sarmento PL, Plavnik FL, Zanella MT, et al. Association of carotid intima-media thickness and cardiovascular risk factors in women pre- and post-bariatric surgery. Obes Surg. 2009 Mar;19(3):339–344.
   PubMed Web of Science ®Google Scholar
• Sturm W, Tschoner A, Engl J, et al. Effect of bariatric surgery on both functional and structural measures of premature atherosclerosis. Eur Heart J. 2009 Aug;30(16):2038–2043.
   PubMed Web of Science ®Google Scholar
• Tarzia P, Lanza GA, Sestito A, et al. Long-term effects of bariatric surgery on peripheral endothelial function and coronary microvascular function. Obes Res Clin Pract. 2017 Jan - Feb;11(1):114–117.
   PubMed Web of Science ®Google Scholar
• Tschoner A, Sturm W, Gelsinger C, et al. Long-term effects of weight loss after bariatric surgery on functional and structural markers of atherosclerosis. Obesity (Silver Spring, Md). 2013 Oct;21(10):1960–1965.
   PubMed Web of Science ®Google Scholar
• Adams TD, Gress RE, Smith SC, et al. Long-term mortality after gastric bypass surgery. N Engl J Med. 2007 Aug 23;357(8):753–761.
   PubMed Web of Science ®Google Scholar
• Corretti MC, Anderson TJ, Benjamin EJ, et al. Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery: a report of the international brachial artery reactivity task force. J Am Coll Cardiol. 2002 Jan 16;39(2):257–265.
   PubMed Web of Science ®Google Scholar
• Hu YJ, Wei AN, Chook P, et al. Impact of non-cardiovascular surgery on reactive hyperaemia and arterial endothelial function. Clin Exp Pharmacol Physiol. 2013 Jul;40(7):466–472.
   PubMed Web of Science ®Google Scholar
• McIlroy DR, Chan MT, Wallace SK, et al. Automated preoperative assessment of endothelial dysfunction and risk stratification for perioperative myocardial injury in patients undergoing non-cardiac surgery. Br J Anaesth. 2014 Jan;112(1):47–56.
   PubMed Web of Science ®Google Scholar
• Sondergaard ES, Fonnes S, Gogenur I. Endothelial dysfunction after non-cardiac surgery: a systematic review. Acta Anaesthesiol Scand. 2015 Feb;59(2):140–146.
   PubMed Web of Science ®Google Scholar
• van Mil A, Pouwels S, Wilbrink J, et al. Carotid artery reactivity predicts events in peripheral arterial disease patients. Ann Surg. 2017 Oct 23.
   Web of Science ®Google Scholar
• Brevetti G, Silvestro A, Schiano V, et al. Endothelial dysfunction and cardiovascular risk prediction in peripheral arterial disease: additive value of flow-mediated dilation to ankle-brachial pressure index. Circulation. 2003 Oct 28;108(17):2093–2098.
   PubMed Web of Science ®Google Scholar
• Ekeloef S, Larsen MH, Schou-Pedersen AM, et al. Endothelial dysfunction in the early postoperative period after major colon cancer surgery. Br J Anaesth. 2017 Feb;118(2):200–206.
   PubMed Web of Science ®Google Scholar
• Ekeloef S, Godthaab C, Schou-Pedersen AMV, et al. Peri-operative endothelial dysfunction in patients undergoing minor abdominal surgery: an observational study. Eur J Anaesthesiol. 2018 Dec 12.
   Web of Science ®Google Scholar
• Bukal K, Ruzic A, Bazdaric K, et al. Total knee replacement surgery is followed by transitory endothelial dysfunction. Coll Antropol. 2012 Jun;36(2):611–616.
   PubMedGoogle Scholar
• Myles PS, Chan MT, Kaye DM, et al. Effect of nitrous oxide anesthesia on plasma homocysteine and endothelial function. Anesthesiology. 2008 Oct;109(4):657–663.
   PubMed Web of Science ®Google Scholar
• Ekeloef S, Oreskov JO, Falkenberg A, et al. Endothelial dysfunction and myocardial injury after major emergency abdominal surgery: a prospective cohort study. BMC Anesthesiol. 2020 Mar 16;20(1):67.
   PubMed Web of Science ®Google Scholar