Hypoglycaemic activity of saponin fraction extracted from Momordica charantia in PEG/salt aqueous two-phase systems

References

• Murakami , T , Emoto , A , Matsuda , H and Yoshikawa , M . 2001 . Medicinal foodstuffs. XXI. Structures of new cucurbitane-type triterpene glycosides, goyaglycosides-a, -b, -c, -d, -e, -f, -g, and -h, and new oleanane-type triterpene saponins, goyasaponins I, II, and III, from the fresh fruit of Japanese Momordica charantia L . Chem. Pharm. Bull. (Tokyo) , 49 : 54 – 63 .
   PubMed Web of Science ®Google Scholar
• Guevara , AP , Lim-Sylianco , C , Dayrit , F and Finch , P . 1990 . Antimutagens from Momordica charantia . Mutat. Res. , 230 : 121 – 126 .
   PubMedGoogle Scholar
• Jilka , C , Strifler , B , Fortner , GW , Hays , EF and Takemoto , DJ . 1983 . In vivo antitumor activity of the bitter melon (Momordica charantia) . Cancer Res. , 43 : 5151 – 5155 .
   Google Scholar
• Ng , TB , Chan , WY and Yeung , HW . 1992 . Proteins with abortifacient, ribosome inactivating, immunomodulatory, antitumor and anti-AIDS activities from Cucurbitaceal plants . Gen. Pharmacol. , 23 : 579 – 590 .
   PubMedGoogle Scholar
• Karunanayake , EH and Tennekoon , KH . 1993 . “ Search of novel hypoglycaemic agents from medicinal plants ” . In Diabetes Mellitus and its Complications, an Update , Edited by: Sharma , AK . 192 – 205 . New Delhi, , India : Macmillan .
   Google Scholar
• Platel , K and Srinivasan , K . 1997 . Plants foods in the management of diabetes mellitus: Vegetables as potential hypoglycemic agents . Nahrung , 41 : 68 – 74 .
   PubMedGoogle Scholar
• Jaspreet , V . 2003 . Antihyperglycemic effects of three extracts from Momordica charantia L . J. Ethnopharmacol. , 88 : 107 – 111 .
   Google Scholar
• Oishi , Y , Sakamoto , T and Udagawa , H . 2007 . Inhibition of increases in blood glucose and serum neutral fat by Momordica charantia saponin fraction . Biosci. Biotech. Biochem. , 71 : 735 – 740 .
   PubMed Web of Science ®Google Scholar
• Harinantenaina , L , Tanaka , M , Takaoka , S , Oda , M , Mogami , O Uchida , M . 2006 . Momordica charantia constituents and antidiabetic screening of the isolated major compounds . Chem. Pharma. Bull. , 54 : 1017 – 1021 .
   PubMed Web of Science ®Google Scholar
• Kimura , Y , Akihisa , T and Yuasa , N . 2005 . Cucurbitane-type triterpenoids from the fruit of Momordica charantia . J. Nat. Prod. , 68 : 807 – 809 .
   PubMed Web of Science ®Google Scholar
• Eiteman , MA and Gainer , JL . 1990 . Peptide hydrophobicity and partitioning in poly(ethylene glycol)/magnesium sulfate aqueous two-phase systems . Biotechnol. Prog. , 6 : 479 – 484 .
   PubMedGoogle Scholar
• Walter , H , Brooks , DE and Fisher , D . 1985 . Partitioning in Aqueous Two-phase Systems: Theory, Methods, Uses, and Applications to Biotechnology , Orlando, FL : Academic Press .
   Google Scholar
• Li , C , Ouyang , F and Bai , J . 2000 . Extractive cultivation of Lactococcus lactis using a poly(ethylene glycol)/MgSO4-7H2O aqueous two-phase systems to produce nisin . Biotechnol. Lett. , 22 : 843 – 847 .
   Web of Science ®Google Scholar
• Pan , IH , Chiu , HH and Lu , CH . 2002 . Aqueous two-phase extraction as an effective tool for isolation of geniposide from gardenia fruit . J. Chromatogr. A , 22 : 239 – 246 .
   Google Scholar
• You , Y and Lin , Z . 2003 . Antioxidant effect of Ganoderma polysaccharide peptide . Acta Pharmacol. Sin. , 38 : 85 – 88 .
   Google Scholar
• Anderson , L , Dinesen , B , Jorgenson , P , Poulsen , F and Roder , M . 1993 . Enzyme immunoassay for intact human insulin in serum or plasma . Clin. Chem. , 8 : 578
   Google Scholar
• Keppler , D and Decker , K . 1974 . “ Glycogen ” . In Methods of Enzymatic Analysis , Edited by: Bergmeyer , HU . 11 – 17 . New York : Academic Press .
   Google Scholar
• Duncan , DB . 1957 . Multiple range tests for correlated and heteroscedastic means . Biometrics , 13 : 164 – 176 .
   Web of Science ®Google Scholar
• Grover , JK , Yadav , S and Vats , V . 2002 . Medicinal plants of India with anti-diabetic potential . J. Ethnopharmacol. , 81 ( 1 ) : 81 – 100 .
   PubMed Web of Science ®Google Scholar
• Shibib , BA , Khan , LA and Rahman , R . 1993 . Hypoglycemic activity of Coccinia indica and Momordica charantia in diabetic rats: Depression of the hepatic gluconeogenic enzymes glucose-6-phosphatase and fructose-1, 6-biphosphatase and elevation of both liver and red-cell shunt enzyme glucose-6-phosphate dehydrogenase . Biochem. J. , 292 : 267 – 270 .
   PubMed Web of Science ®Google Scholar
• Leatherdale , BA , Pansar , RK , Singh , G , Atkins , TW , Bailey , CJ and Bignell , AHC . 1981 . Improvement in glucose tolerance due to Momordica charantia (Karela) . Brit. Med. J. , 282 : 1823 – 1824 .
   PubMed Web of Science ®Google Scholar
• Oishi , Y , Sakamoto , T , Udagawa , H , Taniguchi , H and Kobayashi-Hattori , K . 2007 . Inhibition of increases in blood glucose and serum neutral fat by Momordica charantia saponin fraction . Biosci. Biotech. Biochem. , 71 ( 3 ) : 735 – 740 .
   PubMed Web of Science ®Google Scholar