Advanced search
Publication Cover
Natural Product Research
Formerly Natural Product Letters
Volume 29, 2015 - Issue 4
Submit an article Journal homepage
134
Views
8
CrossRef citations to date
0
Altmetric
Short Communication

Chitooligosaccharides prevent osteopenia by promoting bone formation and suppressing bone resorption in ovariectomised rats: possible involvement of COX-2

Bingshu HeDepartment of Orthopedic Surgery, Hubei Woman and Child Hospital, Wuhan430070, China
&
Jun WangDepartment of Pharmacology, College of Medicine, Wuhan University of Science and Technology, Wuhan430065, P.R. ChinaCorrespondence[email protected]
Pages 359-362 | Received 09 May 2014, Accepted 03 Jul 2014, Published online: 30 Jul 2014

References

  • FernandesJC, SpindolaH, de SousaV, Santos-SilvaA, PintadoME, MalcataFX, CarvalhoJE. 2010. Anti-inflammatory activity of chitooligosaccharides in vivo. Mar Drugs. 8:1763–1768.
  • GuoY, ZhangCY, TianY, DIJM, QinS. 2012. Effect of cyclooxygenase-2 on bone loss in ovariectomized rats. Zhonghua Fu Chan Ke Za Zhi. 47:458–462.
  • JungWK, MoonSH, KimSK. 2006. Effect of chitooligosaccharides on calcium bioavailability and bone strength in ovariectomized rats. Life Sci. 78:970–976.
  • KimHM, HongSH, YooSJ, BaekKS, JeonYJ, ChounSY. 2006. Differential effects of chitooligosaccharides on serum cytokine levels in aged subjects. J Med Food. 9:427–430.
  • LacativaPG, FariasML. 2010. Osteoporosis and inflammation. Arq Bras Endocrinol Metabol. 54:123–132.
  • LavetiD, KumarM, HemalathaR, SistlaR, NaiduVG, TallaV, VermaV, KaurN, NagpalR. 2013. Anti-inflammatory treatments for chronic diseases: a review. Inflamm Allergy Drug Targets. 12:349–361.
  • LeeSH, SenevirathneM, AhnCB, KimSK, JeJY. 2009. Factors affecting anti-inflammatory effect of chitooligosaccharides in lipopolysaccharides-induced RAW264.7 macrophage cells. Bioorg Med Chem Lett. 19:6655–6658.
  • MaZ, BaiL. 2012. The anti-inflammatory effect of Z-Ligustilide in experimental ovariectomized osteopenic rats. Inflammation. 35:1793–1797.
  • PaganiF, FrancucciCM, MoroL. 2005. Markers of bone turnover: biochemical and clinical perspectives. J Endocrinol Invest. 28:8–13.
  • PangestutiR, BakSS, KimSK. 2011. Attenuation of pro-inflammatory mediators in LPS-stimulated BV2 microglia by chitooligosaccharides via the MAPK signaling pathway. Int J Biol Macromol. 49:599–606.
  • RichardsJB, JosephL, SchwartzmanK, KreigerN, TenenhouseA, GoltzmanD, Canadian Multicentre Osteoporosis Study Group. 2006. The effect of cyclooxygenase-2 inhibitors on bone mineral density: results from the Canadian Multicentre Osteoporosis Study. Osteoporos Int. 17:1410–1419.
  • VenkatesanJ, PangestutiP, QianZJ, RyuB, KimSK. 2010. Biocompatibility and alkaline phosphatase activity of phosphorylated chitooligosaccharides on the osteosarcoma MG63 cell Line. J Funct Biomater. 1:3–13.
  • WangP, LiXT, SunL, ShenL. 2013. Anti-inflammatory activity of water-soluble polysaccharide of Agaricus blazei Murill on ovariectomized osteopenic rats. Evid Based Complement Alternat Med.2013:164817.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.