Publication Cover
Natural Product Research
Formerly Natural Product Letters
Volume 29, 2015 - Issue 9
482
Views
24
CrossRef citations to date
0
Altmetric
Articles

Geissoschizine methyl ether N-oxide, a new alkaloid with antiacetylcholinesterase activity from Uncaria rhynchophylla

, , , , , & show all
Pages 842-847 | Received 30 Sep 2014, Accepted 16 Nov 2014, Published online: 13 Dec 2014

References

  • AimiN, YamanakaE, ShinmaN, FujiuM, KuritaJ, SakaiS, HaginiwaJ. 1977. Studies on plants containing indole alkaloids. VI. Minor bases of Uncaria rhynchophylla Miq. Chem Pharm Bull. 25:2067–2071.
  • FanL, FanCL, WangY, ZhangXQ, ZhangQW, ZhangJQ, YeWC. 2010. Alkaloids from the leaves of Nauclea officinalis. Acta Pharm Sin. 45:747–751.
  • HeitzmanME, NetoCC, WiniarzE, VaisbergAJ, HammondGB. 2005. Ethnobotany, phytochemistry and pharmacology of Uncaria (Rubiaceae). Phytochemistry. 66:5–29.
  • LauC, KimY, ChiaD, SpielmannN, EiblG, ElashoffD, WeiF, LinYL, MoroA, GroganT, et al. 2013. Role of pancreatic cancer-derived exosomes in salivary biomarker development. J Biol Chem. 288:26888–26897.
  • LounasmaaM, JokelaR, hanhinenP, MiettinenJ, SaloJ. 1995. The Rhazimanine-Bhimberine enigma. J Nat Prod. 58:131–133.
  • MaB, WuC-F, YangJ-Y, WangR, KanoY, YuanD. 2009. Three new alkaloids from the leaves of Uncaria rhynchophylla. Helv Chim Acta. 92:1575–1585.
  • SakaiS, ShinmaN. 1978. The partial synthesis of heteroyohimbine alkaloids; akuammigine, 3-isorauniticine and corynanthe alkaloid; corynantheidine. Chem Pharm Bull. 26:2596–2598.
  • SakakibaraI, TerabayashiS, KuboM, HiguchiM, KomatsuY, OkadaM, TakiK, KameiJ. 1999. Effect on locomotion of indole alkaloids from the hooks of Uncaria plants. Phytomedicine. 6:163–168.
  • SakakibaraI, TerabayashiS, KuboM, HiguchiM, SasakiH, OkadaM. 1999. Evaluation of Gouteng (hooks and stems of Uncariae plants). III. Hypotensive principle from Uncaria rhynchophylla and alteration of its content on extraction process. Nat Med. 53:308–312.
  • ShenZ, EisenreichW, KutchanTM. 1998. Bacterial biotransformation of 3α(S)-strictosidine to the monoterpenoid indole alkaloid vallesiachotamine. Phytochemistry. 48:293–296.
  • TakayamaH, WatanabeT, SekiH, AimiN, SakaiS. 1992. Geissoschizine revisited – definite proof of its stereostructure. Tetrahedron Lett. 33:6831–6834.
  • WangB, YuanD, MaB, XieY, YinJ, KanoY. 2006. Chemical constituents of the leaves of Uncaria rhynchophylla (Miq.) Jacks. Chin J Med Chem. 16:369–372.
  • XinW, HaoG, WangZ. 2009. Alkaloids in Uncaria rhynchophylla. Chin Tradit Herb Drugs. 40:204–207.
  • XuX, LiS, SongQ. 2011. Chemical constituents of the bark of Anthocephalus chinensis. Nat Prod Res Dev. 23:393–398.
  • YangZd, DuanDZ, DuJ, YangMJ, LiS, YaoXJ. 2012. Geissoschizine methyl ether, a corynanthean-type indole alkaloid from Uncaria rhynchophylla as a potential acetylcholinesterase inhibitor. Nat Prod Res. 26:22–28.
  • YuanD, MaB, WuC, YangJ, ZhangL, LiuS, WuL, KanoY. 2008. Alkaloids from the leaves of Uncaria rhynchophylla and their inhibitory activity on NO production in lipopolysaccharide-activated microglia. J Nat Prod. 71:1271–1274.
  • ZhangJ, YangC, WuD. 1999. Chemical constituents of Uncaria rhynchophylla (III). Chin Tradit Herb Drugs. 30:12–14.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.