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Natural Product Research
Formerly Natural Product Letters
Volume 33, 2019 - Issue 11
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Short Communication

Crude extract of Origanum vulgare L. induced cell death and suppressed MAPK and PI3/Akt signaling pathways in SW13 and H295R cell lines

Beatrice RubinDepartment of Medicine (DIMED), O.U. Endocrinology, University of Padova, Padova, Italy
,
Jacopo MansoDepartment of Medicine (DIMED), O.U. Endocrinology, University of Padova, Padova, Italy
,
Halenya MonticelliDepartment of Medicine (DIMED), O.U. Endocrinology, University of Padova, Padova, Italy
,
Loris BertazzaDepartment of Medicine (DIMED), O.U. Endocrinology, University of Padova, Padova, Italy
,
Marco RedaelliAIROB, Associazione Italiana per la Ricerca Oncologica di Base, Padova, Italy;Venetian Institute for Molecular Science and Experimental Technologies, VIMSET, Liettoli di Campolongo Maggiore, Italy
,
Francesca SensiDepartment of Medicine (DIMED), O.U. Endocrinology, University of Padova, Padova, Italy
,
Maira ZorzanDepartment of Molecular Medicine (DMM), University of Padova, Padova, Italy
,
Carla ScaroniDepartment of Medicine (DIMED), O.U. Endocrinology, University of Padova, Padova, Italy
,
Caterina MianDepartment of Medicine (DIMED), O.U. Endocrinology, University of Padova, Padova, Italy
,
Maurizio IacoboneMinimally Invasive Endocrine Surgery Unit, Department of Surgery, Oncology and Gastroenterology (DISCOG), University of Padova, Padova, Italy
,
Decio ArmaniniDepartment of Medicine (DIMED), O.U. Endocrinology, University of Padova, Padova, Italy
,
Cristina BertoliniAIROB, Associazione Italiana per la Ricerca Oncologica di Base, Padova, Italy
,
Susi BarolloDepartment of Medicine (DIMED), O.U. Endocrinology, University of Padova, Padova, Italy
,
Marco BoscaroDepartment of Medicine (DIMED), O.U. Endocrinology, University of Padova, Padova, Italy
&
Raffaele PezzaniDepartment of Medicine (DIMED), O.U. Endocrinology, University of Padova, Padova, Italy;AIROB, Associazione Italiana per la Ricerca Oncologica di Base, Padova, ItalyCorrespondence[email protected]
 show all
Pages 1646-1649 | Received 30 Oct 2017, Accepted 03 Jan 2018, Published online: 15 Jan 2018

References

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  • Pezzani R, Rubin B, Bertazza L, Redaelli M, Barollo S, Monticelli H, Baldini E, Mian C, Mucignat C, Scaroni C, et al. 2016. The aurora kinase inhibitor VX-680 shows anti-cancer effects in primary metastatic cells and the SW13 cell line. Investigational New Drugs. Oct;34:531–540.10.1007/s10637-016-0358-3
  • Pezzani R, Vitalini S, Iriti M. 2017. Bioactivities of Origanum vulgare L.: an update. Phytochem Rev. Sept;6:1253–1268.
  • Savini I, Arnone R, Catani MV, Avigliano L. 2009. Origanum vulgare induces apoptosis in human colon cancer caco2 cells. Mol Cell Endocrinol.61:381–389.10.1080/01635580802582769
  • Vaško L, Vašková J, Fejerčáková A, Mojžišová G, Poráčová J. 2014. Comparison of some antioxidant properties of plant extracts from Origanum vulgare, Salvia officinalis, Eleutherococcus senticosus and Stevia rebaudiana. In Vitro Cell Dev Biol-Animal. Aug;50:614–622.10.1007/s11626-014-9751-4
  • Wang T, Rainey WE. 2012. Human adrenocortical carcinoma cell lines. Mole Cell Endocrinol. Mar 31;351:58–65.10.1016/j.mce.2011.08.041

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