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Natural Product Research
Formerly Natural Product Letters
Volume 33, 2019 - Issue 11
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Research Articles

Four new dammarane-type triterpenes derivatives from hydrolyzate of total Gynostemma pentaphyllum saponins and their bioactivities

Xiaoshu ZhangSchool of Functional Food and Wine, Shenyang Pharmaceutical University, Shenyang, People’s Republic of China;Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, People’s Republic of China
,
Guohui ShiSchool of Functional Food and Wine, Shenyang Pharmaceutical University, Shenyang, People’s Republic of China;Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, People’s Republic of China
,
Mingbing LiuSchool of Functional Food and Wine, Shenyang Pharmaceutical University, Shenyang, People’s Republic of China;Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, People’s Republic of China
,
Rong ChenSchool of Functional Food and Wine, Shenyang Pharmaceutical University, Shenyang, People’s Republic of China;Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, People’s Republic of China
,
Xiaojun WuSchool of Pharmacy, Shenyang Pharmaceutical University, Shenyang, People’s Republic of China
&
Yuqing ZhaoSchool of Functional Food and Wine, Shenyang Pharmaceutical University, Shenyang, People’s Republic of China;Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, People’s Republic of ChinaCorrespondence[email protected]
Pages 1605-1611 | Received 09 Nov 2017, Accepted 10 Jan 2018, Published online: 23 Jan 2018

References

  • Fearon IM, Faux SP. 2009. Oxidative stress and cardiovascular disease: novel tools give (free) radical insight. J Mol Cell Cardiol. 47:372–381.10.1016/j.yjmcc.2009.05.013
  • Hung TM, Thu CV, Cuong TD, Hung NP, Kwack SJ, Huh JI. 2010. Dammarane-type glycosides from Gynostemma pentaphyllum and their effects on IL-4-induced eotaxin expression in human bronchial epithelial cells. J Nat Prod. 73:192–196.10.1021/np9006712
  • Megalli S, Davis NM, Roufogalis BD. 2006. Anti-hyperlipidemic and hypoglycemic effects of Gynostemma pentaphyllum in the Zucker fatty rat. J Pharm Pharm Sci. 9:281–291.
  • Schild L, Chen BH, Makarov P, Kattengell K, Heinitz K, Keilhoff G. 2010. Selective induction of apoptosis in glioma tumour cells by a Gynostemma pentaphyllum extract. Phytomedicine. 17:589–597.10.1016/j.phymed.2009.12.002
  • Suntararuks S, Yoopan N, Rangkadilok N, Worasuttayangkurn L. 2008. Immunomodulatory effects of cadmium and Gynostemma pentaphyllum herbal tea on rat splenocyte proliferation. J Agric Food Chem. 56:9305–9311.10.1021/jf801062z
  • Xie Z, Liu W, Huang H, Slavin M, Zhao Y, Whent M. 2010. Chemical composition of five commercial Gynostemma pentaphyllum samples and their radical scavenging, antiproliferative, and anti-inflammatory properties. J Agric Food Chem. 58:11243–11249.10.1021/jf1026372
  • Yeo J, Kang YJ, Jeon SM, Jung UJ, Lee MK, Song H. 2008. Potential hypoglycemic effect of an ethanol extract of Gynostemma pentaphyllum in C57BL/KsJ-db/db Mice. J Med Food. 11:709–716.10.1089/jmf.2007.0148
  • Yousuf S, Atif F, Ahmad M, Hoda N, Ishrat T, Khan B. 2009. Resveratrol exerts its neuroprotective effect by modulating mitochondrial dysfunctions and associated cell death during cerebral ischemia. Brain Res. 1250:242–253.10.1016/j.brainres.2008.10.068
  • Zhang XS, Cao JQ, Zhao C, Wang XD, Wu XJ, Zhao YQ. 2015. Novel dammarane-type triterpenes isolated from hydrolyzate of total Gynostemma pentaphyllum saponins. Bioorg Med Chem Lett. 25:3095–3099.10.1016/j.bmcl.2015.06.022

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