Dual HIV-1 reverse transcriptase and integrase inhibitors from Limonium morisianum Arrigoni, an endemic species of Sardinia (Italy)

References

• Appendino G, Aviello G, Ballero M, Borrelli F, Fattorusso E, Petrucci F, Santelia FU, Taglialatela-Scafati O. 2005. Cytotoxic germacrane sesquiterpenes from the aerial parts of Santolina insularis. J Nat Prod. 68:853–857.10.1021/np050120q
   PubMed Web of Science ®Google Scholar
• Bicchi C, Rubiolo P, Ballero M, Sanna C, Matteodo M, Esposito F, Zinzula L, Tramontano E. 2009. HIV-1-Inhibiting activity of the essential oil of ridolfia segetum and Oenanthe crocata. Planta Med. 75:1331–1335.10.1055/s-0029-1185546
   PubMed Web of Science ®Google Scholar
• Blainski A, Lopes GC, de Mello JCP. 2013. application and analysis of the folin ciocalteu method for the determination of the total phenolic content from Limonium brasiliense L. Molecules. 18:6852–6865.10.3390/molecules18066852
   PubMed Web of Science ®Google Scholar
• Cagno V, Sgorbini B, Sanna C, Cagliero C, Ballero M, Civra A, Donalisio M, Bicchi C, Lembo D, Rubiolo P. 2017. In vitro anti-herpes simplex virus-2 activity of Salvia desoleana Atzei & V. Picci essential oil. PLoS One. 12(2):e0172322.
   PubMed Web of Science ®Google Scholar
• Carcelli M, Rogolino D, Gatti A, Pala N, Corona A, Caredda A, Tramontano E, Pannecouque C, Naesens L, Esposito F. 2017. Chelation motifs affecting metal-dependent viral enzymes: N’-acylhydrazone ligands as dual target inhibitors of HIV-1 integrase and reverse transcriptase ribonuclease h domain. Front Microbiol. 8:440.
   PubMed Web of Science ®Google Scholar
• Cobucci RNO, Lima PH, de Souza PC, Costa VV, de Mesquita Cornetta, MDC, Fernandes, JV, Gonçalves, AK. 2015. Assessing the impact of HAART on the incidence of defining and non-defining AIDS cancers among patients with HIV/AIDS: A systematic review. J Infect Public Health. 8:1–10.10.1016/j.jiph.2014.08.003
   PubMed Web of Science ®Google Scholar
• Corona A, di Leva FS, Rigogliuso G, Pescatori L, Madia VN, Subra F, Delelis O, Esposito F, Cadeddu M, Costi R, et al. 2016. New insights into the interaction between pyrrolyl diketoacids and HIV-1 integrase active site and comparison with RNase H. Antiviral Res. 134:236–243.10.1016/j.antiviral.2016.09.008
   PubMed Web of Science ®Google Scholar
• Corona A, Meleddu R, Esposito F, Distinto S, Bianco G, Masaoka T, Maccioni E, Menéndez-Arias L, Alcaro S, Le Grice SFJ, et al. 2016. Ribonuclease H/DNA polymerase HIV-1 reverse transcriptase dual inhibitor: mechanistic studies on the Allosteric mode of action of isatin-based compound RMNC6. PLOS ONE. 11:e0147225.10.1371/journal.pone.0147225
   PubMed Web of Science ®Google Scholar
• Cos P, Maes L, Vlietinck A, Pieters L. 2008. Plant-derived leading compounds for chemotherapy of human immunodefiency virus (HIV) infection - An update (1998-2007). Planta Med. 74:1323–1337.10.1055/s-2008-1081314
   PubMed Web of Science ®Google Scholar
• Esposito F, Tramontano E. 2014. Past and future. Current drugs targeting HIV-1 integrase and reverse transcriptase-associated ribonuclease H activity: Single and dual active site inhibitors. Antivir Chem Chemother. 23:129–144.
   PubMedGoogle Scholar
• Esposito F, Sanna C, Del Vecchio C, Cannas V, Venditti A, Corona A, Bianco A, Serrilli AM, Guarcini L, Parolin C, et al. 2013. Hypericum hircinum L. components as new single-molecule inhibitors of both HIV-1 reverse transcriptase-associated DNA polymerase and ribonuclease H activities. Pathog Dis. 68:116–124.10.1111/2049-632X.12051
   PubMed Web of Science ®Google Scholar
• Esposito F, Tintori C, Martini R, Christ F, Debyser Z, Ferrarese R, Cabiddu G, Corona A, Ceresola ER, Calcaterra A, et al. 2015. Kuwanon-L as a New Allosteric HIV-1 integrase inhibitor: molecular modeling and biological evaluation. ChemBioChem. 16:2507–2512.10.1002/cbic.201500385
   PubMed Web of Science ®Google Scholar
• Esposito F, Carli I, Del Vecchio C, Xu L, Corona A, Grandi N, Piano D, Maccioni E, Distinto S, Parolin C, Tramontano E. 2016. Sennoside A, derived from the traditional chinese medicine plant Rheum L., is a new dual HIV-1 inhibitor effective on HIV-1 replication. Phytomedicine. 23:1383–1391.10.1016/j.phymed.2016.08.001
   PubMed Web of Science ®Google Scholar
• Fassina G, Buffa A, Benelli R, Varnier OE, Noonan DM, Albini A. 2002. Polyphenolic antioxidant (-)-epigallocatechin-3-gallate from green tea as a candidate anti-HIV agent. AIDS. 16:939–941.10.1097/00002030-200204120-00020
   PubMed Web of Science ®Google Scholar
• Gadetskaya AV, Tarawneh AH, Zhusupova GE, Gemejiyeva NG, Cantrell CL, Cutler SJ, Ross SA. 2015. Sulfated phenolic compounds from Limonium caspium: Isolation, structural elucidation, and biological evaluation. Fitoterapia. 104:80–85.10.1016/j.fitote.2015.05.017
   PubMed Web of Science ®Google Scholar
• Gambari R, Lampronti I. 2006. Inhibition of immunodeficiency type-1 virus (HIV-1) life cycle by medicinal plant extracts and plant-derived compounds. Adv Phytomedicine. 2:299–311.10.1016/S1572-557X(05)02017-9
   Google Scholar
• Jiang F, Chen W, Yi K, Wu Z, Si Y, Han W, Zhao Y. 2010. The evaluation of catechins that contain a galloyl moiety as potential HIV-1 integrase inhibitors. Clin Immunol. 137:347–356.10.1016/j.clim.2010.08.007
   PubMed Web of Science ®Google Scholar
• Karas D, Ulrichová J, Valentová K. 2017. Galloylation of polyphenols alters their biological activity. Food Chem Toxicol. 105:223–240.10.1016/j.fct.2017.04.021
   PubMed Web of Science ®Google Scholar
• Kitamura K, Honda M, Yoshizaki H, Yamamoto S, Nakane H, Fukushima M, Ono K, Tokunaga T. 1998. Baicalin, an inhibitor of HIV-1 production in vitro. Antiviral Res. 37:131–140.10.1016/S0166-3542(97)00069-7
   PubMed Web of Science ®Google Scholar
• Krafczyk N, Glomb MA. 2008. Characterization of phenolic compounds in rooibos tea. J Agric Food Chem. 56:3368–3376.10.1021/jf703701n
   PubMed Web of Science ®Google Scholar
• Mandrone M, Scognamiglio M, Fiorentino A, Sanna C, Cornioli L, Antognoni F, Bonvicini F, Poli F. 2017. Phytochemical profile and α-glucosidase inhibitory activity of Sardinian Hypericum scruglii and Hypericum hircinum. Fitoterapia. 120:184–193.10.1016/j.fitote.2017.06.020
   PubMed Web of Science ®Google Scholar
• Maxia A, Sanna C, Piras A, Porcedda S, Falconieri D, Gonçalves MJMJ, Cavaleiro C, Salgueiro L. 2015. Chemical composition and biological activity of Tanacetum audibertii (Req.) DC. (Asteraceae), an endemic species of Sardinia Island. Italy Ind Crops Prod. 65:472–476.10.1016/j.indcrop.2014.10.039
   Web of Science ®Google Scholar
• Medini F, Fellah H, Ksouri R, Abdelly C. 2014. Total phenolic, flavonoid and tannin contents and antioxidant and antimicrobial activities of organic extracts of shoots of the plant Limonium delicatulum. J Taibah Univ Sci. 8:216–224.10.1016/j.jtusci.2014.01.003
   Google Scholar
• Medini F, Bourgou S, Lalancette K, Snoussi M, Mkadmini K, Coté I, Abdelly C, Legault J, Ksouri R. 2015. Phytochemical analysis, antioxidant, anti-inflammatory, and anticancer activities of the halophyte Limonium densiflorum extracts on human cell lines and murine macrophages. South African J Bot. 99:158–164.10.1016/j.sajb.2015.04.007
   Web of Science ®Google Scholar
• Moharrek F, Kazempour Osaloo S, Assadi M. 2014. Molecular phylogeny of Plumbaginaceae with emphasis on Acantholimon Boiss. based on nuclear and plastid DNA sequences in Iran. Biochem Syst Ecol. 57:117–127.10.1016/j.bse.2014.07.023
   Web of Science ®Google Scholar
• Nagashima H, Murakami T, Yamamoto N, Naoe T, Kawazoe Y, Konno K, Sakagami H. 1992. Lignified materials as medicinal resources. V. Anti-HIV (human immunodeficiency virus) activity of some synthetic lignins. Chem Pharm Bull. 40:2102–2105.10.1248/cpb.40.2102
   PubMed Web of Science ®Google Scholar
• Nance CL, Siwak EB, Shearer WT. 2009. Preclinical development of the green tea catechin, epigallocatechin gallate, as an HIV-1 therapy. J Allergy Clin Immunol. 123:459–465.10.1016/j.jaci.2008.12.024
   PubMed Web of Science ®Google Scholar
• de Oliveira Caleare A, Hensel A, Mello JCP, Pinha AB, Panizzon GP, Lechtenberg M, Petereit F, Nakamura CV. 2017. Flavan-3-ols and proanthocyanidins from Limonium brasiliense inhibit the adhesion of Porphyromonas gingivalis to epithelial host cells by interaction with gingipains. Fitoterapia. 118:87–93.10.1016/j.fitote.2017.03.002
   PubMed Web of Science ®Google Scholar
• Ono K, Nakane H, Fukushima M, Chermann JC, Barre-Sinoussi F. 1990. Differential inhibitory effects of various flavonoids on the activities of reverse transcriptase and cellular DNA and RNA polymerases. Eur J Biochem. 190:469–476.10.1111/ejb.1990.190.issue-3
   PubMedGoogle Scholar
• Ornano L, Venditti A, Sanna C, Ballero M, Maggi F, Lupidi G, Bramucci M, Quassinti L, Bianco A. 2015. Chemical composition and biological activity of the essential oil from Helichrysum microphyllum Cambess. ssp. tyrrhenicum Bacch., Brullo e Giusso growing in La Maddalena Archipelago. Sardinia J Oleo Sci. 64:19–26.10.5650/jos.ess14171
   PubMed Web of Science ®Google Scholar
• Ornano L, Venditti A, Ballero M, Sanna C, Donno Y, Quassinti L, Bramucci M, Vitali LA, Petrelli D, Tirillini B, et al. 2016. Essential oil composition and biological activity from Artemisia caerulescens subsp. densiflora (Viv.) Gamisans ex Kerguélen & Lambinon (Asteraceae), an endemic species in the habitat of La Maddalena Archipelago. Nat Prod Res. 30:1802–1809.10.1080/14786419.2015.1079190
   PubMed Web of Science ®Google Scholar
• Ornano L, Venditti A, Donno Y, Sanna C, Ballero M, Bianco A. 2016. Phytochemical analysis of non-volatile fraction of Artemisia caerulescens subsp. densiflora (Viv.) (Asteraceae), an endemic species of La Maddalena Archipelago (Sardinia – Italy). Nat Prod Res. 30:920–925.10.1080/14786419.2015.1079189
   PubMed Web of Science ®Google Scholar
• Sonar VP, Corona A, Distinto S, Maccioni E, Meleddu R, Fois B, Floris C, Malpure NV, Alcaro S, Tramontano E, et al. 2017. Natural product-inspired esters and amides of ferulic and caffeic acid as dual inhibitors of HIV-1 reverse transcriptase. Eur J Med Chem. 130:248–260.10.1016/j.ejmech.2017.02.054
   PubMed Web of Science ®Google Scholar
• Venditti A, Lattanzi C, Ornano L, Maggi F, Sanna C, Ballero M, Alvino A, Serafini M, Bianco A. 2016. A new glucosidic phthalide from Helichrysum microphyllum subsp. tyrrhenicum from La Maddalena Island (Sardinia, Italy). Nat Prod Res. 30:789–795.10.1080/14786419.2015.1067619
   PubMed Web of Science ®Google Scholar
• Wang YY, Chen C. 2007. Synthesis of deuterium labeled tryptamine derivatives. JCCS. 54:1363–1368.
   Web of Science ®Google Scholar
• Xu H, Lv M. 2009. Developments of indoles as anti-HIV-1 inhibitors. Curr Pharm Des. 15:2120–2148.10.2174/138161209788489168
   PubMed Web of Science ®Google Scholar
• Xu L, Grandi N, Del Vecchio C, Mandas D, Corona A, Piano D, Esposito F, Parolin C, Tramontano E. 2015. From the traditional Chinese medicine plant Schisandra chinensis new scaffolds effective on HIV-1 reverse transcriptase resistant to non-nucleoside inhibitors. J Microbiol. 53:288–293.10.1007/s12275-015-4652-0
   PubMed Web of Science ®Google Scholar
• Yamaguchi K, Honda M, Ikigai H, Hara Y, Shimamura T. 2002. Inhibitory effects of (-)-epigallocatechin gallate on the life cycle of human immunodeficiency virus type 1 (HIV-1). Antiviral Res. 53:19–34.10.1016/S0166-3542(01)00189-9
   PubMed Web of Science ®Google Scholar
• Zhao Y, Jiang F, Liu P, Chen W, Yi K. 2012. Catechins containing a galloyl moiety as potential anti-HIV-1 compounds. Drug Discov Today. 17:630–635.10.1016/j.drudis.2012.02.015
   PubMed Web of Science ®Google Scholar