Advanced search
Publication Cover
Natural Product Research
Formerly Natural Product Letters
Volume 33, 2019 - Issue 18
Submit an article Journal homepage
330
Views
33
CrossRef citations to date
0
Altmetric
Short Communication

Allicin inhibits mouse colorectal tumorigenesis through suppressing the activation of STAT3 signaling pathway

Xiang LiShanghai Kongjiang Senior High School, Shanghai, China
,
Jiahui NiDepartment of Pharmacology, School of Pharmacy, Fudan University, Shanghai, China
,
Yixin TangShanghai Kongjiang Senior High School, Shanghai, China
,
Xu WangDepartment of Pharmacology, School of Pharmacy, Fudan University, Shanghai, China
,
Huanhuan TangDepartment of Pharmacology, School of Pharmacy, Fudan University, Shanghai, China
,
Haidong LiDepartment of Pharmacology, School of Pharmacy, Fudan University, Shanghai, China
,
Sulin ZhangDepartment of Pharmacology, School of Pharmacy, Fudan University, Shanghai, ChinaCorrespondence[email protected]
&
Xiaoyan ShenDepartment of Pharmacology, School of Pharmacy, Fudan University, Shanghai, ChinaCorrespondence[email protected]
 show all
Pages 2722-2725 | Received 14 Feb 2018, Accepted 12 Apr 2018, Published online: 23 Apr 2018

References

  • Ariga T, Seki T. 2006. Antithrombotic and anticancer effects of garlic-derived sulfur compounds: A review. BioFactors. 26:93–103.10.1002/biof.v26:2
  • Bat-Chen W, Golan T, Peri I, Ludmer Z, Schwartz B. 2010. Allicin purified from fresh garlic cloves induces apoptosis in colon cancer cells via Nrf2. Nutr Cancer. 62:947–957.10.1080/01635581.2010.509837
  • Du W, Hong J, Wang YC, Zhang YJ, Wang P, Su WY, Lin YW, Lu R, Zou WP, Xiong H, et al. 2012. Inhibition of JAK2/STAT3 signalling induces colorectal cancer cell apoptosis via mitochondrial pathway. J Cell Mol Med. 16:1878–1888.10.1111/jcmm.2012.16.issue-8
  • Hodge DR, Hurt EM, Farrar WL. 2005. The role of IL-6 and STAT3 in inflammation and cancer. Eur J Cancer. 41:2502–2512.10.1016/j.ejca.2005.08.016
  • Pandurangan AK, Ismail S, Saadatdoust Z, Esa NM. 2015. Allicin alleviates dextran sodium sulfate-(DSS-) induced ulcerative colitis in BALB/c mice. Oxid Med Cell Longev. 2015:605208.
  • Santos CI, Costa-Pereira AP. 2011. Signal transducers and activators of transcription-from cytokine signalling to cancer biology. Biochim Biophys Acta. 1816:38–49.
  • Siddique YH, Beg T, Ara G, Gupta J, Afzal M. 2010. Antigenotoxic effect of allicin against estradiol-17 beta-induced genotoxic damage in cultured mammalian cells. Nat Prod Res. 24:1087–1094.10.1080/14786410802263568
  • Wang Z, Liu Z, Cao Z, Li L. 2012. Allicin induces apoptosis in EL-4 cells in vitro by activation of expression of caspase-3 and -12 and up-regulation of the ratio of Bax/Bcl-2. Nat Prod Res. 26:1033–1037.10.1080/14786419.2010.550894

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.