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Natural Product Research
Formerly Natural Product Letters
Volume 33, 2019 - Issue 19
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Research Articles

Isolation and synthesis of a new benzylated alkamide from the roots of Lepidium meyenii

Yan-Qing YeSchool of Chemistry and Environment, Yunnan Minzu University, Kunming, P.R. China;
,
Zu-Hong MaSchool of Chemistry and Environment, Yunnan Minzu University, Kunming, P.R. China;
,
Qiao-Fen YangSchool of Chemistry and Environment, Yunnan Minzu University, Kunming, P.R. China;
,
Yan-Qi SunSchool of Chemistry and Environment, Yunnan Minzu University, Kunming, P.R. China;
,
Rui-Qi ZhangKey Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan Minzu University, Kunming, P.R. China
,
Run-Fang WuKey Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan Minzu University, Kunming, P.R. China
,
Xin RenKey Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan Minzu University, Kunming, P.R. China
,
Li-Juan MuKey Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan Minzu University, Kunming, P.R. China
,
Zhi-Yong JiangKey Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan Minzu University, Kunming, P.R. ChinaCorrespondence[email protected]
&
Min ZhouSchool of Chemistry and Environment, Yunnan Minzu University, Kunming, P.R. China; ;Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan Minzu University, Kunming, P.R. ChinaCorrespondence[email protected]
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Pages 2731-2737 | Received 26 Apr 2018, Accepted 09 Jul 2018, Published online: 20 Aug 2018

References

  • Bai N, He K, Roller M, Lai CS, Bai L, Pan MH. 2015. Flavonolignans and other constituents from Lepidium meyenii with activities in anti-inflammation and human cancer cell lines. J Agric Food Chem. 63(9):2458–2463.
  • Chain FE, Grau A, Martins JC, Catalán CAN. 2014. Macamides from wild ‘maca’, Lepidium meyenii Walpers (Brassicaceae). Phytochemistry Lett. 8:145–148.
  • Reed LJ, Muench H. 1938. A simple method of estimating fifty percent endpoints. Am J Epidemiol. 27(3):493–497.
  • Rubio J, Yucra S, Gasco M, Gonzales GF. 2011. Dose-response effect of black maca (Lepidium meyenii) in mice with memory impairment induced by ethanol. Toxicol Mech Methods. 21(8):628–634.
  • Tang Y, Zhu ZY, Pan LC, Sun HQ, Song QY, Zhang YM. 2018. Structure analysis and anti-fatigue activity of a polysaccharide from Lepidium meyenii Walp. Nat Prod Res. 1. https://doi.org/10.1080/14786419.2018.1452017.
  • Uchiyama F, Jikyo T, Takeda R, Ogata M. 2014. Lepidium meyenii (maca) enhances the serum levels of luteinising hormone in female rats. J Ethnopharmacol. 151(2):897–902.
  • Vecera R, Orolin J, Skottová N, Kazdová L, Oliyarnik O, Ulrichová J, Simánek V. 2007. The influence of maca (Lepidium meyenii) on antioxidant status, lipid and glucose metabolism in rat. Plant Foods Hum Nutr. 62(2):59–63.
  • Wang W, Zou Y, Li Q, Mao RW, Shao XJ, Jin D, Zheng DH, Zhao T, Zhu HF, Zhang L, et al. 2016. Immunomodulatory effects of a polysaccharide purified from Lepidium meyenii Walp. on macrophages. Process Biochem. 51(4):542–553.
  • Wang Y, Wang Y, McNeil B, Harvey LM. 2007. Maca: an Andean crop with multi-pharmacological functions. Food Res Int. 40(7):783–792.
  • Wu H, Kelley CJ, Pino-Figueroa A, Vu HD, Maher TJ. 2013. Macamides and their synthetic analogs: evaluation of in vitro FAAH inhibition. Bioorg Med Chem. 21(17):5188–5197.
  • Yu MY, Qin XJ, Shao LD, Peng XR, Li L, Yang H, Qiu MH. 2017. Macahydantoins A and B, two new thiohydantoin derivatives from maca (Lepidium meyenii): structural elucidation and concise synthesis of macahydantoin A. Tetrahedron Lett. 58(17):1684–1686.
  • Zheng BL, He K, Kim CH, Rogers L, Shao Y, Huang ZY, Lu Y, Yan SJ, Qien LC, Zheng QY. 2000. Effect of a lipidic extract from Lepidium meyenii on sexual behavior in mice and rats. Urology. 55(4):598–602.
  • Zhou M, Ma HY, Liu ZH, Yang GY, Du G, Ye YQ, Li GP, Hu QF. 2017. (+)-Meyeniins A − C, novel hexahydroimidazo[1,5-c]thiazole derivatives from the tubers of Lepidium meyenii: complete structural elucidation by biomimetic synthesis and racemic crystallization. J Agric Food Chem. 65:1887–1892.
  • Zhou M, Ma HY, Xing HH, Li P, Li GP, Geng HC, Hu QF, Yang GY. 2017. Biomimetic synthesis of macahydantoins A and B from Lepidium meyenii, and structure revision of macahydantoin B as a class of thiohydantoin with a 4-methyl-hexahydropyrrolo[1,2-c]imidazole skeleton. Org Lett. 19(18):4952–4955.
  • Zhou M, Zhang RQ, Chen YJ, Liao LM, Sun YQ, Ma ZH, Yang QF, Li P, Ye YQ, Hu QF. 2018. Three new pyrrole alkaloids from the roots of Lepidium meyenii. Phytochemistry Lett. 23:137–140.
  • Zhou M, Zhou K, Gao XM, Jiang ZY, Lv JJ, Liu ZH, Yang GY, Miao MM, Che CT, Hu QF. 2015. Fistulains A and B, new bischromones from the bark of Cassia fistula, and their activities. Org Lett. 17:2638–2641.

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