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Natural Product Research
Formerly Natural Product Letters
Volume 34, 2020 - Issue 2
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Linear regression analysis of silychristin A, silybin A and silybin B contents in Silybum marianum

Sameh F. AbouZidDepartment of Pharmacognosy, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt; Correspondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-0789-767X
ORCID Icon,
Hayam S. AhmedDepartment of Pharmacognosy, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt; ORCID Iconhttp://orcid.org/0000-0002-7379-3078
ORCID Icon,
Abd-El Mageed A. Abd El MageedDepartment of Pharmacognosy, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt; ORCID Iconhttp://orcid.org/0000-0002-4582-0606
ORCID Icon,
Abeer S. MoawadDepartment of Pharmacognosy, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt; ORCID Iconhttp://orcid.org/0000-0002-0228-6757
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Asmaa I. OwisDepartment of Pharmacognosy, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt; ORCID Iconhttp://orcid.org/0000-0003-1860-9124
ORCID Icon,
Shao-Nong ChenUIC/NIH Center for Botanical Dietary Supplements Research, Chicago, IL, USA; ;Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA; ORCID Iconhttp://orcid.org/0000-0003-0748-0863
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Amandine NachtergaelDepartment of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA; ORCID Iconhttp://orcid.org/0000-0002-8697-2809
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James B. McAlpineDepartment of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA; ORCID Iconhttp://orcid.org/0000-0003-1696-8828
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J. Brent FriesenDepartment of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA; ;Physical Sciences Department, Rosary College of Arts and Sciences, Dominican University, River Forest, IL, USAORCID Iconhttp://orcid.org/0000-0002-0739-9224
ORCID Icon &
Guido F. PauliUIC/NIH Center for Botanical Dietary Supplements Research, Chicago, IL, USA; ;Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA; ORCID Iconhttp://orcid.org/0000-0003-1022-4326
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Pages 305-310 | Received 23 Jul 2018, Accepted 20 Sep 2018, Published online: 29 Nov 2018

References

  • AbouZid S, Chen SN, Pauli GF. 2016. Silymarin content in Silybum marianum populations growing in Egypt. Ind Crops Prod. 83:729–737.
  • AbouZid S, Ahmed HS, Moawad AS, Owis AI, Chen CN, Nachtergael A, McAlpine JB, Friesen JB, Pauli GF. 2017. Chemotaxonomic and biosynthetic relationships between flavonolignans produced by Silybum marianum populations. Fitoterapia. 119:175–184.
  • Andrzejewska J, Sadowska K, Mielcarek S. 2011. Effect of sowing date and rate on the yield and flavonolignan content of the fruits of milk thistle (Silybum marianum L. Gaertn.) grown on light soil in a moderate climate. Ind Crop Prod. 33(2):462–468.
  • Cheilari A, Sturm S, Intelmann D, Seger C, Stuppner H. 2016. Head-to-head comparison of ultra-high-performance liquid chromatography with diode array detection versus quantitative nuclear magnetic resonance for the quantitative analysis of the silymarin complex in Silybum marianum fruit extracts. J Agric Food Chem. 64(7):1618–1626.
  • Elwekeel A, AbouZid S, Sokkar N, Elfishway A. 2012. Studies on flavanolignans from cultured cells of Silybum marianum. Acta Physiol Plant. 34(4):1445–1449.
  • Kim NC, Graf TN, Sparacino CM, Wani MC, Wall ME. 2003. Complete isolation and characterization of silybins and isosilybins from milk thistle (Silybum marianum). Org Biomol Chem. 1(10):1684–1689.
  • Kroll DJ, Shaw HS, Oberlies NH. 2007. Milk thistle nomenclature: why it matters in cancer research and pharmacokinetic studies. Integr Cancer Ther. 6(2):110–119.
  • Lv Y, Gao S, Xu S, Du G, Zhou J, Chen J. 2017. Spatial organization of silybin biosynthesis in milk thistle [Silybum marianum (L.) Gaertn]. Plant J. 92(6):995–1004.
  • Martinelli T, Potenza E, Moschella A, Zaccheria F, Benedettelli S, Andrzejewska J. 2016. Phenotypic evaluation of a milk thistle germplasm collection: fruit morphology and chemical composition. Crop Sci. 56(6):3160–3172.
  • Martinelli T, Whittaker A, Benedettelli S, Carboni A, Andrzejewska J. 2017. The study of flavonolignan association patterns in fruits of diverging Silybum marianum (L.) Gaertn. chemotypes provides new insights into the silymarin biosynthetic pathway. Phytochemistry. 144:9–18.
  • Napolitano JG, Lankin DC, Graf TN, Friesen JB, Chen JB, McAlpine JB, Oberlies NH, Pauli GF. 2013. HiFSA fingerprinting applied to isomers with near-identical NMR spectra: the silybin/isosilybin case. J Org Chem. 78(7):2827–2839.
  • Rahal NB, Barba FJ, Barth D, Chevalot I. 2015. Supercritical CO2 extraction of oil, fatty acids and flavonolignans from milk thistle seeds: Evaluation of their antioxidant and cytotoxic activities in Caco-2 cells. Food Chem Toxicol. 83:275–282.
  • Shokrpour M, Mohammadi SA, Moghaddam M, Ziai SA, Javanshir A. 2008. Variation in flavonolignan concentration of milk thistle (Silybum marianum) fruits grown in Iran. J Herbs Spices Med Plant. 13(4):55–69.

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