References
- AbouZid S. 2014. Yield improvement strategies for the production of secondary metabolites in plant tissue culture: silymarin from Silybum marianum tissue culture. Nat Prod Res. 28:2102–2110.
- AbouZid SF, Ahmed HS, Abd El Mageed AEMA, Moawad AS, Owis AI, Chen SN, Nachtergael A, McAlpine JB, Friesen JB, Pauli GF. 2018. Linear regression analysis of silychristin A, silybin A and silybin B contents in Silybum marianum. Nat Prod Res. doi.org/10.1080/14786419.2018.1527838.
- Chen X, Sun CK, Han GZ, Peng JY, Li Y, Liu YX, Lv YY, Liu KX, Zhou Q, Sun HJ. 2009. Protective effect of tea polyphenols against paracetamol-induced hepatotoxicity in mice is significantly correlated with cytochrome P450 suppression. World J Gastroenterol. 15:1829–1835.
- Cho BO, So Y, Jin CH, Nam BM, Yee ST, Jeong IY. 2014. 3-Deoxysilybin exerts anti-inflammatory effects by suppressing NF-κB activation in lipopolysaccharide-stimulated RAW264.7 macrophages. Biosci Biotechnol Biochem. 78:2051–2058.
- Ferenci P. 2016. Silymarin in the treatment of liver diseases: what is the clinical evidence?. Clin Liver Dis. 7:8–10.
- Fiebig M, Wagner H. 1984. New antihepatotoxic effects of flavonolignans of a white flowering variety of Silybum. Planta Med. 50:310–313.
- Hikino H, Kiso Y, Wagner H, Fiebig M. 1984. Antihepatotoxic actions of flavonolignans from Silybum marianum fruits. Planta Med. 50:248–250.
- Kiran PM, Raju AV, Rao BG. 2012. Investigation of hepatoprotective activity of Cyathea gigantea (Wall. ex. Hook.) leaves against paracetamol–induced hepatotoxicity in rats. Asian Pac J Trop Biomed. 2:352–356.
- Mahadevan SB, McKiernan PJ, Davies P, Kelly DA. 2006. Paracetamol induced hepatotoxicity. Arch Dis Child. 91:598–603.
- Morazzoni P, Bombardelli E. 1995. Silybum marianum (Carduus marianus). Fitoterapia. 66:3–42.
- Rahimi S, Hasanloo T, Najafi F, Khavari-Nejad RA. 2012. Methyl jasmonate influence on silymarin production and plant stress responses in Silybum marianum hairy root cultures in a bioreactor. Nat Prod Res. 26:1662–1667.
- Samu Z, Nyiredy S, Baitz‐Gács E, Varga Z, Kurtán T, Dinya Z, Antus S, 2004. Structure elucidation and antioxidant activity of (−)‐isosilandrin isolated from Silybum marianum L. Chem Biodiver. 1:1668–1677.
- Saller R, Meier R, Brignoli R. 2001. The use of silymarin in the treatment of liver diseases. Drugs. 61:2035–2063.
- Szilági I, Tétényi P, Antus S, Seligmann O, Chari VM, Seitz M, Wagner H. 1981. Structure of silandrin and silymonin, two new flavanolignans from a white blooming Silybum marianum variety. Planta Med. 43:121–127.