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Natural Product Research
Formerly Natural Product Letters
Volume 35, 2021 - Issue 22
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Phloroglucinol derivatives from Hypericum species induce in vitro proliferation of cells involved in the wound healing process

Henrique Bridia Laboratório de Farmacognosia, Faculdade de Farmácia, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, Brazil
,
Aline Beckenkampb Laboratório de Análises Bioquímicas e Citológicas, Faculdade de Farmácia, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, Brazil
,
Natasha Maurmannc Laboratório de Hematologia e Células-Tronco, Faculdade de Farmácia, e Instituto de Pesquisa Com Células-Tronco (IPCT), Universidade Federal Do Rio Grande Do Sul, Porto Alegre, Brazil
,
Bianca Elingsona Laboratório de Farmacognosia, Faculdade de Farmácia, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, Brazil
,
Andréia Buffonb Laboratório de Análises Bioquímicas e Citológicas, Faculdade de Farmácia, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, Brazil
,
Patricia Prankec Laboratório de Hematologia e Células-Tronco, Faculdade de Farmácia, e Instituto de Pesquisa Com Células-Tronco (IPCT), Universidade Federal Do Rio Grande Do Sul, Porto Alegre, Brazil
&
Gilsane Lino von Posera Laboratório de Farmacognosia, Faculdade de Farmácia, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, BrazilCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-2527-7500
ORCID Icon show all
Pages 4648-4652 | Received 24 Sep 2019, Accepted 17 Nov 2019, Published online: 04 Dec 2019

References

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  • Bridi H, Beckenkamp A, Ccana-Ccapatinta GV, Bordignon SAL, Buffon A, von Poser GL. 2017. Characterization of phloroglucinol-enriched fractions of Brazilian Hypericum species and evaluation of their effect on human keratinocytes proliferation. Phytother Res. 31(1):62–68.
  • Das U, Behera SS, Pramanik K. 2017. Ethno-Herbal-Medico in wound repair: an incisive review. Phytother Res. 31(4):579–590.
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  • Özkan EE, Mat A. 2013. An overview on Hypericum species of Turkey. J Pharmacogn Phytother. 5:38–46.
  • Shaw TJ, Martin P. 2009. Wound repair at a glance. J Cell Sci. 122(18):3209–3213.
  • Shaw TJ, Martin P. 2016. Wound repair: a showcase for cell plasticity and migration. Curr Opin Cell Biol. 42:29–37.
  • Takada H, Furuya K, Sokabe M. 2014. Mechanosensitive ATP release from hemichannels and Ca2+ influx through TRPC6 accelerate wound closure in keratinocytes. J Cell Sci. 127(19):4159–4171.
  • Takada H, Yonekawa J, Matsumoto M, Furuya K, Sokabe M. 2017. Hyperforin/HP-β-cyclodextrin enhances mechanosensitive Ca2+ signaling in HaCaT keratinocytes and in atopic skin ex vivo which accelerates wound healing. Biomed Res Int. 2017:1.
  • Wölfle U, Seelinger G, Schempp C. 2013. Topical Application of St. Johnʼs Wort (Hypericum perforatum). Planta Med. 80(02/03):109–120.

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