Publication Cover
Natural Product Research
Formerly Natural Product Letters
Volume 35, 2021 - Issue 22
360
Views
8
CrossRef citations to date
0
Altmetric
Research Articles

Cytotoxic effects of flavonoids from root of Sophora flavescens in cancer cells

, , , , , & show all
Pages 4317-4322 | Received 29 Aug 2019, Accepted 26 Dec 2019, Published online: 13 Jan 2020

References

  • Bernier J, Bentzen SM. 2006. Radiotherapy for head and neck cancer: Latest developments and future perspectives. Curr Opin Oncol. 18(3):240–246.
  • Boulares AH, Yakovlev AG, Ivanova V, Stoica BA, Wang G, Iyer S, Smulson M. 1999. Role of Poly(ADP-ribose) Polymerase (PARP) Cleavage in Apoptosis. J Biol Chem. 274(33):22932–22940.
  • Cao W, Gu Y, Meineck M, Xu H. 2014. The combination of chemotherapy and radiotherapy towards more efficient drug delivery. Chem Asian J. 9(1):48–57.
  • Créhange G, Huguet F, Quero L, N’Guyen TV, Mirabel X, Lacornerie T. 2016. Radiothérapie des cancers de l’oesophage, du cardia et de l’estomac. Cancer/Radiotherapie. 20:S161–S168.
  • De Naeyer A, Vanden Berghe W, Pocock V, Milligan S, Haegeman G, De Keukeleire D. 2004. Estrogenic and anticarcinogenic properties of Kurarinone, a lavandulyl flavanone from the roots of Sophora flavescens. J Nat Prod. 67(11):1829–1832.
  • Elmore S. 2007. Apoptosis: A review of programmed cell death. Toxicol Pathol. 35(4):495–516.
  • Huang R, Liu Y, Zhao LL, Chen XX, Wang F, Cai W, Chen L. 2017. A new flavonoid from Sophora flavescens Ait. Nat Prod Res. 31(19):2228–2232. [Internet]. Available from: http://dx.doi.org/10.1080/14786419.2017.1297992.
  • Jung J, Kang SS, Woo JJ, Choi JS. 2005. A new lavandulylated flavonoid with free radical and onoo-scavenging activities from Sophora flavescens. Arch Pharm Res. 28(12):1333–1336.
  • Jung YY, Shanmugam MK, Narula AS, Kim C, Lee JH, Namjoshi OA, Blough BE, Sethi G, Ahn KS. 2019. Oxymatrine attenuates tumor growth and deactivates STAT5 signaling in a lung cancer xenograft model. Cancers. 11(1):49.
  • Kang T-H, Jeong S-J, Ko W-G, Kim N-Y, Lee B-H, Inagaki M, Miyamoto T, Higuchi R, Kim Y-C. 2000. Cytotoxic lavandulyl flavanones from Sophora flavescens. J Nat Prod. 63(5):680–681.
  • Kim YC, Kim H-S, Wataya Y, Sohn DH, Kang TH, Kim MS, … Park H. 2004. Antimalarial activity of lavandulyl flavanones isolated from the roots of Sophora flavescens. Biol Pharm Bull. 27(5):748–750.
  • Mabry TJ, Markham KR, Thomas MB. 1970. The systematic indentification of flavonoids. Berlin: Springer-Verlag, p. 41–61.
  • Sohn HY, Son KH, Kwon CS, Kwon GS, Kang SS. 2004. Antimicrobial and cytotoxic activity of 18 prenylated flavonoids isolated from medicinal plants: Morus alba L., Morus mongolica Schneider, Broussnetia papyrifera (L.) Vent, Sophora flavescens Ait and Echinosophora koreensis Nakai. Phytomedicine. 11(7–8):666–672.
  • Vanden Berghe W, De Naeyer A, Dijsselbloem N, David J.-P, De Keukeleire D, Haegeman G. 2012. Attenuation of ERK/RSK2-driven NFκB gene expression and cancer cell proliferation by Kurarinone, a lavandulyl flavanone isolated from Sophora flavescens Ait. Roots. EMIDDT. 11(3):247–261.
  • Zhou GZ, Shi YY, Cui LS, Li AF, Wang QQ, Liu M. 2018. Oxymatrine induces A549 human non-small lung cancer cell apoptosis via extrinsic and intrinsic pathways. Mol Med Report. 17(1):1071–1076.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.