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Natural Product Research
Formerly Natural Product Letters
Volume 35, 2021 - Issue 23
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Short Communications

In-vitro antitumor activity of compounds from Glycyrrhiza glabra against C6 glioma cancer cells: identification of natural lead for further evaluation

Bharat Goela Department of Pharmaceutical Engineering and Technology, Indian Institute of Technology, Banaras Hindu University, Varanasi, IndiaORCID Iconhttps://orcid.org/0000-0002-6297-0067View further author information
ORCID Icon,
Anuradha Sharmab Department of Biotechnology, Guru Nanak Dev University, Amritsar, IndiaView further author information
,
Nancy Tripathia Department of Pharmaceutical Engineering and Technology, Indian Institute of Technology, Banaras Hindu University, Varanasi, IndiaView further author information
,
Nivedita Bhardwaja Department of Pharmaceutical Engineering and Technology, Indian Institute of Technology, Banaras Hindu University, Varanasi, IndiaView further author information
,
Bharat Sahua Department of Pharmaceutical Engineering and Technology, Indian Institute of Technology, Banaras Hindu University, Varanasi, IndiaView further author information
,
Gurcharan Kaurb Department of Biotechnology, Guru Nanak Dev University, Amritsar, IndiaView further author information
,
Bikarma Singhc Biodiversity and Applied Botany Division, Indian Institute of Integrative Medicine (Council of Scientific and Industrial Research), Jammu, IndiaView further author information
&
Shreyans K. Jaina Department of Pharmaceutical Engineering and Technology, Indian Institute of Technology, Banaras Hindu University, Varanasi, IndiaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-6160-8755View further author information
ORCID Icon show all
Pages 5489-5492 | Received 01 May 2020, Accepted 10 Jun 2020, Published online: 01 Jul 2020

References

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  • Chen C-T, Chen Y-T, Hsieh Y-H, Weng C-J, Yeh J-C, Yang S-F, Lin C-W, Yang J-S. 2018. Glabridin induces apoptosis and cell cycle arrest in oral cancer cells through the JNK1/2 signaling pathway. Environ Toxicol. 33(6):679–685.
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  • Sharma R, Gatchie L, Williams IS, Jain SK, Vishwakarma RA, Chaudhuri B, Bharate SB. 2017. Glycyrrhiza glabra extract and quercetin reverses cisplatin resistance in triple-negative MDA-MB-468 breast cancer cells via inhibition of cytochrome P450 1B1 enzyme. Bioorg Med Chem Lett. 27(24):5400–5403.
  • Sharma A, Saggu SK, Mishra R, Kaur G. 2019. Anti-brain cancer activity of chloroform and hexane extracts of Tinospora cordifolia Miers: an in vitro perspective. Ann Neurosci. 26(1):10–20.
  • Shults EE, Shakirov MM, Pokrovsky MA, Petrova TN, Pokrovsky AG, Gorovoy PG. 2017. Phenolic compounds from Glycyrrhiza pallidiflora Maxim. and their cytotoxic activity. Nat Prod Res. 31(4):445–452.
  • U.S. National Library of Medicine. 2014. Licorice root extract and docetaxel in treating patients with metastatic prostate cancer that did not respond to hormone therapy. [accessed 2020 Mar 14]. https://clinicaltrials.gov/ct2/show/NCT00176631.

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