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Natural Product Research
Formerly Natural Product Letters
Volume 35, 2021 - Issue 23
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Short Communication

Antidepressant potential of Mesembryanthemum cordifolium roots assisted by metabolomic analysis and virtual screening

Asmaa Abo Elgoud Saida Faculty of Pharmacy, Department of Pharmacognosy, Minia University, Minia, Egypt
,
Taha F. S. Alib Faculty of Pharmacy, Department of Medicinal Chemistry, Minia University, Minia, EgyptCorrespondence[email protected] [email protected]
ORCID Iconhttps://orcid.org/0000-0002-8881-0408
ORCID Icon,
Eman Zekry Attiaa Faculty of Pharmacy, Department of Pharmacognosy, Minia University, Minia, Egypt
,
Al-Shaimaa F. Ahmedc Faculty of Pharmacy, Department of Pharmacology & Toxicology, Minia University, Minia, Egypt
,
Alaa H. Shehatac Faculty of Pharmacy, Department of Pharmacology & Toxicology, Minia University, Minia, Egypt
,
Usama Ramadan Abdelmohsena Faculty of Pharmacy, Department of Pharmacognosy, Minia University, Minia, Egypt;d Faculty of Pharmacy, Department of Pharmacognosy, Deraya University, New Minia, Egypt
&
Mostafa Ahmed Fouada Faculty of Pharmacy, Department of Pharmacognosy, Minia University, Minia, Egypt
 show all
Pages 5493-5497 | Received 19 Mar 2020, Accepted 10 Jun 2020, Published online: 01 Jul 2020

References

  • Carpenter JM, Jourdan MK, Fountain EM, Ali Z, Abe N, Khan IA, Sufka KJ. 2016. The effects of Sceletium tortuosum (L.) N.E. Br. extract fraction in the chick anxiety-depression model. J Ethnopharmacol. 193:329–332.
  • Daina A, Michielin O, Zoete V. 2017. SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules. Sci Rep. 7(1):42717.
  • Daina A, Zoete V. 2016. A boiled-egg to predict gastrointestinal absorption and brain penetration of small molecules. ChemMedChem. 11(11):1117–1121.
  • Gfeller D, Michielin O, Zoete V. 2013. Shaping the interaction landscape of bioactive molecules. Bioinformatics. 29(23):3073–3079.
  • Krstenansky JL. 2017. Mesembrine alkaloids: review of their occurrence, chemistry, and pharmacology. J Ethnopharmacol. 195:10–19.
  • Malikowska N, Fijałkowski Ł, Nowaczyk A, Popik P, Sałat K. 2017. Antidepressant-like activity of venlafaxine and clonidine in mice exposed to single prolonged stress – A model of post-traumatic stress disorder. Pharmacodynamic and molecular docking studies. Brain Res. 1673:1–10.
  • Rani K U, Ramaiah M, Nagaphani K, Preethi V, Srinadh M. 2014. Screening for antidepressant-like effect of methanolic seed extract of avena sativa using animal models. Phcog J. 6(3):86–92.
  • Shao L, Hewitt MC, Malcolm SC, Wang F, Ma J, Campbell UC, Spicer NA, Engel SR, Hardy LW, Jiang Z-D, et al. 2011. Synthesis and pharmacological characterization of bicyclic triple reuptake inhibitor 3-aryl octahydrocyclopenta[c]pyrrole analogues. J Med Chem. 54(15):5283–5295.
  • Terburg D, Syal S, Rosenberger LA, Heany S, Phillips N, Gericke N, Stein DJ, van Honk J. 2013. Acute effects of Sceletium tortuosum (Zembrin), a dual 5-HT reuptake and PDE4 inhibitor, in the human amygdala and its connection to the hypothalamus. Neuropsychopharmacology. 38(13):2708–2716.
  • Zoete V, Daina A, Bovigny C, Michielin O. 2016. SwissSimilarity: a web tool for low to ultra high throughput ligand-based virtual screening. J Chem Inf Model. 56(8):1399–1404.

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