Induction of apoptosis in human bladder cancer cells by triterpenoids isolated from Holarrhena antidysenterica through differential reactive oxygen species generation

References

• Bhattachartya S, Tarafdar S, Saha CN. 2009. Triterpenoids and steroids from Holarrhena pubescens seeds. Pharmacogn Mag. 5:407.
   Web of Science ®Google Scholar
• Daniel M, Mammen D. 2016. Analytical methods for medicinal plants and economic botany. Jodhpur (India): Scientific Publishers.
   Google Scholar
• Elyashberg M. 2015. Identification and structure elucidation by NMR spectroscopy. Trac Trends Anal Chem. 69:88–97.
   Web of Science ®Google Scholar
• Ghosh A, Sarkar A, Mitra P, Banerji A, Banerji J, Mandal S, Das M. 2010. Crystal structure and DFT calculations of 3, 4-seco-lup-20 (29)-en-3-oic acid isolated from Wrightia tinctoria: stacking of supramolecular dimers in the crystal lattice. J Mol Struct. 980(1–3):7–12.
   Web of Science ®Google Scholar
• Guru SK, Pathania AS, Kumar S, Ramesh D, Kumar M, Rana S, Kumar A, Malik F, Sharma PR, Chandan BK, et al. 2015. Secalonic acid-D represses HIF1α/VEGF-mediated angiogenesis by regulating the Akt/mTOR/p70S6K signaling cascade. Cancer Res. 75(14):2886–2896.,
   PubMed Web of Science ®Google Scholar
• Hordyjewska A, Ostapiuk A, Horecka A, Kurzepa J. 2019. Betulin and betulinic acid: triterpenoids derivatives with a powerful biological potential. Phytochem Rev. 18(3):929–951.
   Web of Science ®Google Scholar
• Kalim MD, Bhattacharyya D, Banerjee A, Chattopadhyay S. 2010. Oxidative DNA damage preventive activity and antioxidant potential of plants used in Unani system of medicine. BMC Complement Altern Med. 10:77.
   PubMed Web of Science ®Google Scholar
• Kasibhatla S, Amarante-Mendes GP, Finucane D, Brunner T, Bossy-Wetzel E, Green DR. 2006. Acridine orange/ethidium bromide (AO/EB) staining to detect apoptosis. Cold Spring Harbor Protocol. 2006(21):pdb.prot4493.
   Google Scholar
• Khafif A, Schantz SP, Chou T-C, Edelstein D, Sacks PG. 1998. Quantitation of chemopreventive synergism between (-)-epigallocatechin-3-gallate and curcumin in normal, premalignant and malignant human oral epithelial cells. Carcinogenesis. 19(3):419–424.
   PubMed Web of Science ®Google Scholar
• Król SK, Kiełbus M, Rivero-Müller A, Stepulak A. 2015. Comprehensive review on betulin as a potent anticancer agent. Biomed Res Int. 2015:584189.
   PubMed Web of Science ®Google Scholar
• Kumar A, Ali M. 2000. A new steroidal alkaloid from the seeds of Holarrhena antidysenterica. Fitoterapia. 71(2):101–104.
   PubMed Web of Science ®Google Scholar
• Kumar N, Singh B, Bhandari P, Gupta AP, Kaul VK. 2007. Steroidal alkaloids from Holarrhena antidysenterica (L.) WALL. Chem Pharm Bull. 55(6):912–914.
   PubMed Web of Science ®Google Scholar
• Li Y, Liu X, Jiang D, Lin Y, Wang Y, Li Q, Liu L, Jin Y-H. 2016. Betulin induces reactive oxygen species-dependent apoptosis in human gastric cancer SGC7901 cells. Arch Pharm Res. 39(9):1257–1265.
   PubMed Web of Science ®Google Scholar
• Potze L, Mullauer F, Colak S, Kessler J, Medema J. 2014. Betulinic acid-induced mitochondria-dependent cell death is counterbalanced by an autophagic salvage response. Cell Death Dis. 5:e1169.
   PubMed Web of Science ®Google Scholar
• Roy R, Pal D, Sur S, Mandal S, Saha P, Panda CK. 2019. Pongapin and Karanjin, furanoflavanoids of Pongamia pinnata, induce G2/M arrest and apoptosis in cervical cancer cells by differential reactive oxygen species modulation, DNA damage, and nuclear factor kappa-light-chain-enhancer of activated B cell signaling. Phytother Res. 33(4):1084–1094.
   PubMed Web of Science ®Google Scholar
• Sadhu SK, Khatun A, Ohtsuki T, Ishibashi M. 2008. Constituents from Hoya parasitica and their cell growth inhibitory activity. Planta Med. 74(7):760–763.
   PubMed Web of Science ®Google Scholar
• Shah BN. 2009. Textbook of pharmacognosy and phytochemistry. New Delhi: Elsevier India.
   Google Scholar
• Sharma V, Hussain S, Bakshi M, Bhat N, Saxena AK. 2014. In vitro cytotoxic activity of leaves extracts of Holarrhena antidysenterica against some human cancer cell lines. Ind J Biochem Biophys. 51(1):46–71.
   PubMed Web of Science ®Google Scholar
• Singh L, Pushker N, Saini N, Sen S, Sharma A, Bakhshi S, Chawla B, Kashyap S. 2015. Expression of pro-apoptotic Bax and anti-apoptotic Bcl-2 proteins in human retinoblastoma. Clin Exp Ophthalmol. 43(3):259–267.
   PubMed Web of Science ®Google Scholar
• Srivastava R. 2014. A review on phytochemical, pharmacological, and pharmacognostical profile of Wrightia tinctoria: adulterant of kurchi. Pharmacogn Rev. 8(15):36–44.
   PubMedGoogle Scholar
• Sur S, Pal D, Roy R, Barua A, Roy A, Saha P, Panda CK. 2016. Tea polyphenols EGCG and TF restrict tongue and liver carcinogenesis simultaneously induced by N-nitrosodiethylamine in mice. Toxicol Appl Pharmacol. 300:34–46.
   PubMed Web of Science ®Google Scholar
• Tijjani A, Ndukwe I, Ayo R. 2012. Isolation and characterization of lup-20 (29)-ene-3, 28-diol (Betulin) from the stem-bark of Adenium obesum (Apocynaceae). Trop J Pharm Res. 11(2):259–262.
   Web of Science ®Google Scholar
• Vichai V, Kirtikara K. 2006. Sulforhodamine B colorimetric assay for cytotoxicity screening. Nat Protoc. 1(3):1112–1116.
   PubMed Web of Science ®Google Scholar
• Wang D, Liu J, Yin MZ, Li XT, Lou G, Liu Y, Chen X. 2012. Betulin induces apoptosis of HeLa cell lines in vitro and its possible mechanism. Tumour. 32:234–238.
   Google Scholar
• Xie H, Su J, Ge X, Dong T, Li X, Wen H, Sun B. 2018. Compounds with inhibitory activity on peristalsis from the seeds of Holarrhena antidysenterica. Nat Prod Res. 32(4):418–424.
   PubMed Web of Science ®Google Scholar
• Yamamoto Y, Kobayashi Y, Devi SR, Rikiishi S, Matsumoto H. 2003. Oxidative stress triggered by aluminum in plant roots. In: Roots: the dynamic interface between plants and the earth. New York: Springer; p. 239–243.
   Google Scholar
• Zhao Y, Truhlar DG. 2008. Density functionals with broad applicability in chemistry. Acc Chem Res. 41(2):157–167.
   PubMed Web of Science ®Google Scholar
• Zhou Z, Zhu C, Cai Z, He L, Zhao F, Lou X, Qi X. 2018. Betulin induces cytochrome c release and apoptosis in colon cancer cells via NOXA. Oncol Lett. 15(5):7319–7327.
   PubMed Web of Science ®Google Scholar