Publication Cover
Natural Product Research
Formerly Natural Product Letters
Volume 35, 2021 - Issue 24
327
Views
4
CrossRef citations to date
0
Altmetric
Short Communications

Bixa orellana L. by-products’ fractions from an industrial process: antiproliferative activity on tumor cells and chemical profile

, , , , &
Pages 6106-6111 | Received 06 Jul 2020, Accepted 05 Sep 2020, Published online: 04 Oct 2020

References

  • Anantharaman A, Hemachandran H, Mohan S, Manikoth Ayyathan D, D TK, C GPD, Siva R. 2016. Induction of apoptosis by apocarotenoids in B16 melanoma cells through ROS-mediated mitochondrial-dependent pathway. J Funct Foods. 20:346–357.
  • Anders CK, Adamo B, Karginova O, Deal AM, Rawal S, Darr D, Schorzman A, Santos C, Bash R, Kafri T, et al. 2013. Pharmacokinetics and efficacy of PEGylated liposomal doxorubicin in an intracranial model of breast cancer. PLoS One. 8(5):e61359
  • Cardarelli CR, Benassi MT, Mercadante AZ. 2008. Characterization of different annatto extracts based on antioxidant and colour properties. LWT-Food Sci Technol. 41(9):1689–1693.
  • Carvalho PRN. 2015. INPI – Instituto Nacional da Propriedade Intelectual. 08 Dec 15. Extração e concentração dos componentes insaponificáveis das sementes de urucum. Brazil patent BR102015029422.
  • de Oliveira Júnior RG, Bonnet A, Braconnier E, Groult H, Prunier G, Beaugeard L, Grougnet R, Almeida JRGS, Ferraz CAA, Picot L. 2019. Bixin, an apocarotenoid isolated from Bixa orellana L., sensitizes human melanoma cells to dacarbazine-induced apoptosis through ROS-mediated cytotoxicity. Food Chem Toxicol. 125:549–561.
  • Ferreira A, Cunha-Oliveira T, Simões RF, Carvalho FS, Burgeiro A, Nordgren K, Wallace KB, Oliveira PJ. 2017. Altered mitochondrial epigenetics associated with subchronic doxorubicin cardiotoxicity. Toxicology. 390:63–73.
  • Liby KT, Yore MM, Sporn MB. 2007. Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer. Nat Rev Cancer. 7(5):357–369.
  • Lourido Perez HDL, Martinez Sanchez G. 2010. The Bixa orellana L. in treatment of stomatology affections: A subject that hasn't studied yet. Rev Cubana Farm. 44(2):221–234.
  • Lüpertz R, Wätjen W, Kahl R, Chovolou Y. 2010. Dose- and time-dependent effects of doxorubicin on cytotoxicity, cell cycle and apoptotic cell death in human colon cancer cells. Toxicology. 271(3):115–121.
  • Pereira MF, Martino T, Dalmau SR, Paes MC, Barja-Fidalgo C, Albano RM, Coelho MGP, Sabino KCC. 2012. Terpenic fraction of Pterodon pubescens inhibits nuclear factor kappa B and extracellular signal-regulated protein kinase 1/2 activation and deregulates gene expression in leukemia cells. BMC Complement Altern Med. 12:231.
  • Rabi T, Bishayee A. 2009. Terpenoids and breast cancer chemoprevention. Breast Cancer Res Treat. 115(2):223–239.
  • Raddatz-Mota D, Pérez-Flores LJ, Carrari F, Mendoza-Espinoza JA, de León-Sánchez FD, Pinzón-López LL, Godoy-Hernández G, Rivera-Cabrera F. 2017. Achiote (Bixa orellana L.): a natural source of pigment and vitamin E. J Food Sci Technol. 54(6):1729–1741.
  • Santos G, Almeida M, Antunes L, Bianchi M. 2016. Effect of bixin on DNA damage and cell death induced by doxorubicin in HL60 cell line. Hum Exp Toxicol. 35(12):1319–1327.
  • Shahid-Ul-Islam Rather LJ, Mohammad F. 2016. Phytochemistry, biological activities and potential of annatto in natural colorant production for industrial applications – A review. J Adv Res. 7(3):499–514.
  • Taymaz-Nikerel H, Karabekmez ME, Eraslan S, Kırdar B. 2018. Doxorubicin induces an extensive transcriptional and metabolic rewiring in yeast cells. Sci Rep. 8(1):13672.
  • Teixeira da Silva JA, Dobránszki J, Rivera-Madrid R. 2018. The biotechnology (genetic transformation and molecular biology) of Bixa orellana L. (achiote). Planta. 248(2):267–277.
  • Zegarra L, Vaisberg A, Loza C, Aguirre RL, Campos M, Fernandez I, Talla O, Villegas L. 2007. Double-blind randomized placebo-controlled study of Bixa orellana in patients with lower urinary tract symptoms associated to benign prostatic hyperplasia. Int Braz J Urol. 33(4):493–501.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.