Advanced search
Publication Cover
Natural Product Research
Formerly Natural Product Letters
Volume 35, 2021 - Issue 24
Submit an article Journal homepage
217
Views
3
CrossRef citations to date
0
Altmetric
Short Communications

The in vitro and in vivo anti-inflammatory activities of triterpene saponins from Clematis florida

Na-Na Yanga Fujian Provincial Key Laboratory of Natural Medicine Pharmacology, School of Pharmacy, Fujian Medical University, Fuzhou, P. R. ChinaView further author information
,
Yi-Fan Zhangb Medical Imaging Department, First Affiliated Hospital of Fujian Medical University, Fuzhou, P. R. ChinaView further author information
,
Hai-Tao Zhanga Fujian Provincial Key Laboratory of Natural Medicine Pharmacology, School of Pharmacy, Fujian Medical University, Fuzhou, P. R. ChinaView further author information
,
Xin-Hua Maa Fujian Provincial Key Laboratory of Natural Medicine Pharmacology, School of Pharmacy, Fujian Medical University, Fuzhou, P. R. ChinaView further author information
,
Jin-Huang Shena Fujian Provincial Key Laboratory of Natural Medicine Pharmacology, School of Pharmacy, Fujian Medical University, Fuzhou, P. R. ChinaView further author information
,
Peng Lia Fujian Provincial Key Laboratory of Natural Medicine Pharmacology, School of Pharmacy, Fujian Medical University, Fuzhou, P. R. ChinaView further author information
,
Tian-Hua Zhongc Key Laboratory of Marine Biogenetic Resources, Third Institute of Oceanography, State Oceanic Administration, Xiamen, P. R. ChinaView further author information
&
Yong-Hong Zhanga Fujian Provincial Key Laboratory of Natural Medicine Pharmacology, School of Pharmacy, Fujian Medical University, Fuzhou, P. R. ChinaCorrespondence[email protected]
View further author information
 show all
Pages 6180-6183 | Received 08 Aug 2020, Accepted 16 Sep 2020, Published online: 14 Oct 2020

References

  • Cheng L, Shi L, Wu J, Zhou X, Li X, Sun X, Zhu L, Xia TS, Ding Q. 2018. A hederagenin saponin isolated from Clematis ganpiniana induces apoptosis in breast cancer cells via the mitochondrial pathway. Oncol Lett. 15(2):1737–1743.
  • Editorial Committee of Flora of China. 1980. Chinese flora. Beijing: Science Press. Vol. 28; p. 209–211.
  • Firestein GS. 2005. Immunologic mechanisms in the pathogenesis of rheumatoid arthritis. J Clin Rheumatol. 11(3 Suppl):S39–S44.
  • Fu Q, Chen J, Yuan HM, Ma Y, Yu T, Zou L. 2016. Alkaloids and phenolic glycosides from Clematis mandshurica and their inhibitory effects against NO production in LPS-induced RAW 246.7 macrophages. Phytochem Lett. 17:238–241.
  • Fu Q, Qiu L, Yuan HM, Du YF, Cheng XL, Tang TT, Wang P, Xu L, Liang JM, Yang LF, et al. 2017. Triterpenoid saponins from Clematis chinensis and their inhibitory activities on NO production. Phytochem Lett. 21(9):206–210.
  • Fu Q, Yang M, Ma Y, Chen J, Yuan HM. 2018. Novel triterpene saponins isolated from Clematis mandshurica and their inhibitory activities on NO production. Chin J Nat Med. 16(2):131–138.
  • Hackett TL, Holloway R, Holgate ST, Warner JA. 2008. Dynamics of pro-inflammatory and anti-inflammatory cytokine release during acute inflammation in chronic obstructive pulmonary disease: an ex vivo study. Respir Res. 9(5):47–60.
  • Hwang SY, Kim J, Kim K, Park M, Moon Y, Kim W, Kim H. 2004. IL-17 induces production of IL-6 and IL-8 in rheumatoid arthritis synovial fibroblasts via NF-κB- and P13-kinase/Akt-dependent pathways. Arthritis Res Ther. 6 (2):R120–R128.
  • Kizu H, Shimana H, Tomimori T. 1995. Studies on the constituents of Clematis species. VI. The constituents of Clematis stans Sieb. et Zucc. Chem Pharm Bull. 43(12):2187–2194.
  • Sun KH, Ma XH, Zeng XM, Lin ZY, Cai YM, Zhang HT, Lin XY, Feng SB, Zhong TH, Zhang YH. 2019. A new indole-type alkaloid from the roots of Clematis florida var. plena. Nat Prod Res. 33(20):2925–2931.
  • Zhang LJ, Huang HT, Huang SY, Lin ZH, Shen CC, Tsai W, Kuo Y. 2015. Antioxidant and anti-inflammatory phenolic glycosides from Clematis tashiroi. J Nat Prod. 78(7):1586–1592.
  • Zhao M, Da-Wa ZM, Guo DL, Fang D, Chen XZ, Xu HX, Gu YC, Xia B, Chen L, Ding LS, et al. 2016. Cytotoxic triterpenoid saponins from Clematis tangutica. Phytochemistry. 130(10):228–237.
  • Zhu F, Li Y, He S, Chen Q, Xu X. 2018. Cytotoxic activities of total saponins from plena Clematis on human tumor cell lines in vitro. Chin J Integr Med. 24(10):763–767.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.