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Natural Product Research
Formerly Natural Product Letters
Volume 37, 2023 - Issue 7
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Short Communications

A new β-class milbemycin derivative from a mutant of genetically engineered strain Streptomyces avermitilis AVE-H39

Huan Qia Key Laboratory of Vector Biology and Pathogen Control of Zhejiang Province, College of Life Science, Huzhou University, Huzhou, ChinaView further author information
,
Cheng-Hong Zhanga Key Laboratory of Vector Biology and Pathogen Control of Zhejiang Province, College of Life Science, Huzhou University, Huzhou, ChinaView further author information
,
Shao-Yong Zhanga Key Laboratory of Vector Biology and Pathogen Control of Zhejiang Province, College of Life Science, Huzhou University, Huzhou, ChinaView further author information
,
Wen-Shuai Songb Life Science and Biotechnology Research Center, School of Life Science, Northeast Agricultural University, Harbin, ChinaView further author information
,
Wen-Sheng Xiangb Life Science and Biotechnology Research Center, School of Life Science, Northeast Agricultural University, Harbin, ChinaView further author information
,
Li-Qin Zhanga Key Laboratory of Vector Biology and Pathogen Control of Zhejiang Province, College of Life Science, Huzhou University, Huzhou, ChinaView further author information
&
Ji-Dong Wanga Key Laboratory of Vector Biology and Pathogen Control of Zhejiang Province, College of Life Science, Huzhou University, Huzhou, ChinaCorrespondence[email protected]
View further author information
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Pages 1212-1216 | Received 08 Jun 2021, Accepted 19 Sep 2021, Published online: 08 Oct 2021

References

  • Delić V, Hopwood DA, Friend EJ. 1970. Mutagenesis by N-methyl-N'-nitro-N-nitro-soguanidine (NTG) in Streptomyces coelicolor. Mutat Res. 9(2):167–182.
  • Geurden T, Chartier C, Fanke J, di Regalbono AF, Traversa D, von Samson-Himmelstjerna G, Demeler J, Vanimisetti HB, Bartram DJ, Denwood MJ. 2015. Anthelmintic resistance to ivermectin and moxidectin in gastrointestinal nematodes of cattle in Europe. Int J Parasitol Drugs Drug Resist. 5(3):163–171.
  • Goss RJM, Shankar S, Fayad AA. 2012. The generation of "unnatural" products: synthetic biology meets synthetic chemistry. Nat Prod Rep. 29(8):870–889.
  • Ikeda H, Ishikawa J, Hanamoto A, Shinose M, Kikuchi H, Shiba T, Sakaki Y, Hattori M, Omura S. 2003. Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis. Nat Biotechnol. 21(5):526–531.
  • Ikeda H, Nonomiya T, Usami M, Ohta T, Omura S. 1999. Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis. Proc Natl Acad Sci U S A. 96(17):9509–9514.
  • Nonaka K, Tsukiyama T, Okamoio Y, Sato K, Kumasaka C, Yamamoto T, Maruyama F, Yoshikawa H. 2000. New milbemycins from Streptomyces hygroscopicus subsp. Aureolacrimosus: fermentation, isolation and structure elucidation. J Antibiot. 53(7):694–704.
  • Olano C, Méndez C, Salas JA. 2010. Post-pks tailoring steps in natural product-producing actinomycetes from the perspective of combinatorial biosynthesis. Nat Prod Rep. 27(4):571–616.
  • Qi H, Zhang J, Hao Z-K, Zhang S-Y, Li J-S, Zhang L-Q, Wang J-D, Xiang W-S. 2020. Two novel milbemycin derivatives from the genetically engineered strain Streptomyces avermitilis AVE-H39. J Antibiot (Tokyo)). 73(9):642–645.
  • Srikrai S, Robbers JE. 1983. Methods for mutation and selection of the ergot fungus. Appl Environ Microbiol. 45(4):1165–1169.
  • Wang J-D, Qi H, Zhang J, Li J-S, Zhang S-Y, Hao Z-K, Zhang L-Q, Xiang W-S. 2020. Two new 13-hydroxylated milbemycin metabolites from the genetically engineered strain Streptomyces avermitilis AVE-H39. J Asian Nat Prod Res. :1–7. doi:10.1080/10286020.2020.1803294.
  • Wang LH, Wu YD. 2007. Cross-resistance and biochemical mechanisms of abamectin resistance in the b-type bemisia tabaci. J Appl Entomol. 131(2):98–103.
  • Wang LY, Huang ZL, Li G, Zhao HX, Xing XH, Sun WT, Li HP, Gou ZX, Bao CY. 2010. Novel mutation breeding method for Streptomyces avermitilis using an atmospheric pressure glow discharge plasma. J Appl Microbiol. 108(3):851–858.
  • Zhang H, Feng YL, Zhang SY, Huang J, Xue ZL, Wang JD. 2020. Two new sixteen-membered macrolides from the genetically engineered strain Streptomyces avermitilis MHJ1011. Nat Prod Res. 34(20):2959–2963.
  • Zhang J, Yan YJ, An J, Huang SH, Wang XJ, Xiang WS. 2015. Designed biosynthesis of 25-methyl and 25-ethyl ivermectin with enhanced insecticidal activity by domain swap of avermectin polyketide synthase. Microb Cell Fact. 14:152–163.

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