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Natural Product Research
Formerly Natural Product Letters
Volume 36, 2022 - Issue 22
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Short Communications

Resveratrol activates GABAA and/or glycine receptors on substantia gelatinosa neurons of the subnucleus caudalis in mice

Seon Hui Janga Department of Oral Physiology, School of Dentistry & Institute of Oral Bioscience, Jeonbuk National University, Jeonju, Republic of KoreaView further author information
,
Soo Joung Parka Department of Oral Physiology, School of Dentistry & Institute of Oral Bioscience, Jeonbuk National University, Jeonju, Republic of KoreaView further author information
,
Kyoung-A Kimb Department of Oral and Maxillofacial Radiology, School of Dentistry& Institute of Oral Bioscience, Jeonbuk National University, Jeonju, Republic of Korea;c Research Institute of Clinical Medicine, of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju, Republic of KoreaCorrespondence[email protected] [email protected]
View further author information
&
Seong Kyu Hana Department of Oral Physiology, School of Dentistry & Institute of Oral Bioscience, Jeonbuk National University, Jeonju, Republic of Korea;c Research Institute of Clinical Medicine, of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju, Republic of KoreaCorrespondence[email protected] [email protected]
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Pages 5788-5792 | Received 31 May 2021, Accepted 30 Nov 2021, Published online: 28 Jan 2022

References

  • Bazzo KO, Souto AA, Lopes TG, Zanin RF, Gomez MV, Souza AH, Campos MM. 2013. Evidence for the analgesic activity of resveratrol in acute models of nociception in mice. J Nat Prod. 76(1):13–21.
  • Budai D. 2000. Neurotransmitters and receptors in the dorsal horn of the spinal cord. Acta Biologica Szegediensis. 44(1–4):21–38.
  • Chai R, Chen Y, Yuan H, Wang X, Guo S, Qi J, Zhang H, Zhan Y, An H. 2017. Identification of resveratrol, an herbal compound, as an activator of the calcium-activated chloride channel, TMEM16A. J Membr Biol. 250(5):483–492.
  • Das S, Das DK. 2007. Anti-inflammatory responses of resveratrol. Inflamm Allergy Drug Targets. 6(3):168–173.
  • Fremont L. 2000. Biological effects of resveratrol. Life Sci. 66(8):663–673.
  • Gao ZB, Hu GY. 2005. Trans-resveratrol, a red wine ingredient, inhibits voltage-activated potassium currents in rat hippocampal neurons. Brain Res. 1056(1):68–75.
  • Granados-Soto V, Arguelles CF, Ortiz MI. 2002. The peripheral antinociceptive effect of resveratrol is associated with activation of potassium channels. Neuropharmacology. 43(5):917–923. English.
  • Groundwater PW, Hamid K, Ng I, Tallapragada VJ, Hibbs DE, Hanrahan J. 2015. The differential effects of resveratrol and trans-ε-viniferin on the GABA-induced current in GABAA receptor subtypes expressed in Xenopus laevis oocytes. J Pharm Pharm Sci. 18(4):328–338.
  • Lee BH, Choi SH, Hwang SH, Kim HJ, Lee JH, Nah SY. 2013. Resveratrol inhibits GABAC ρ receptor-mediated ion currents expressed in Xenopus oocytes . Korean J Physiol Pharmacol. 17(2):175–180.
  • Lee BH, Hwang SH, Choi SH, Kim HJ, Jung SW, Kim HS, Lee JH, Kim HC, Rhim H, Nah SY. 2014. Resveratrol inhibits glycine receptor-mediated ion currents. Biol Pharm Bull. 37(4):576–580.
  • Lee BH, Hwang SH, Choi SH, Shin TJ, Kang J, Lee SM, Nah SY. 2011. Resveratrol enhances 5-hydroxytryptamine type 3A receptor-mediated ion currents: the role of arginine 222 residue in pre-transmembrane domain I. Biol Pharm Bull. 34(4):523–527.
  • Li Y, Yu L, Zhao L, Zeng F, Liu QS. 2017. Resveratrol modulates cocaine-induced inhibitory synaptic plasticity in VTA dopamine neurons by inhibiting phosphodiesterases (PDEs). Sci Rep. 7(1):15657.
  • Pervaiz S. 2003. Resveratrol: from grapevines to mammalian biology. FASEB J. 17(14):1975–1985.
  • Pham-Marcou TA, Beloeil H, Sun X, Gentili M, Yaici D, Benoit G, Benhamou D, Mazoit JX. 2008. Antinociceptive effect of resveratrol in carrageenan-evoked hyperalgesia in rats: prolonged effect related to COX-2 expression impairment. Pain. 140(2):274–283.
  • Sharma S, Kulkarni SK, Chopra K. 2007. Effect of resveratrol, a polyphenolic phytoalexin, on thermal hyperalgesia in a mouse model of diabetic neuropathic pain. Fundam Clin Pharmacol. 21(1):89–94.
  • Shibuta K, Suzuki I, Shinoda M, Tsuboi Y, Honda K, Shimizu N, Sessle BJ, Iwata K. 2012. Organization of hyperactive microglial cells in trigeminal spinal subnucleus caudalis and upper cervical spinal cord associated with orofacial neuropathic pain. Brain Res. 1451:74–86. English.
  • Singh AK, Vinayak M. 2016. Anti-nociceptive effect of resveratrol during inflammatory hyperalgesia via differential regulation of pro-inflammatory mediators. Phytother Res. 30(7):1164–1171.
  • Wang LL, Shi DL, Gu HY, Zheng MZ, Hu J, Song XH, Shen YL, Chen YY. 2016. Resveratrol attenuates inflammatory hyperalgesia by inhibiting glial activation in mice spinal cords. Mol Med Rep. 13(5):4051–4057. English.
  • Yang YJ, Hu L, Xia YP, Jiang CY, Miao C, Yang CQ, Yuan M, Wang L. 2016. Resveratrol suppresses glial activation and alleviates trigeminal neuralgia via activation of AMPK. J Neuroinflammation. 13(1):84.

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