Advanced search
Publication Cover
Natural Product Research
Formerly Natural Product Letters
Volume 37, 2023 - Issue 17
Submit an article Journal homepage
165
Views
1
CrossRef citations to date
0
Altmetric
Short communications

Antileishmanial anthraquinones from the rhyzomes of Rumex abyssinicus Jacq (Polygonaceae)

Stephanie Tamdem Guetchuenga Centre for Research on Medicinal Plants and Traditional Medicine, Institute of Medical Research and Medicinal Plants Studies, Yaoundé, CameroonView further author information
,
Paul Toukam Djouonzoa Centre for Research on Medicinal Plants and Traditional Medicine, Institute of Medical Research and Medicinal Plants Studies, Yaoundé, CameroonORCID Iconhttps://orcid.org/0000-0002-0362-7170View further author information
ORCID Icon,
Younoussa Lameb Department of Animal Biology and Physiology, Faculty of Science, University of Yaoundé I, Yaoundé, CameroonView further author information
,
Théodora Kopa Kowaa Centre for Research on Medicinal Plants and Traditional Medicine, Institute of Medical Research and Medicinal Plants Studies, Yaoundé, Cameroon;c Natural Products Chemistry Research Unit, Department of Chemistry, Faculty of Sciences, University of Dschang, Dschang, CameroonCorrespondence[email protected]
View further author information
,
Eunice Dotsed Department of Clinical Pathology, Noguchi Memorial Institute for Medical Research (NMIMR), College of Health Sciences (CHS), University of Ghana, Accra, GhanaView further author information
,
Lauve R. Y. Tchokouahaa Centre for Research on Medicinal Plants and Traditional Medicine, Institute of Medical Research and Medicinal Plants Studies, Yaoundé, Cameroon;e Department of Parasitology, Noguchi Memorial Institute for Medical Research (NMIMR), College of Health Sciences (CHS), University of Ghana, Accra, GhanaView further author information
,
Hippolyte Kamdem Waboc Natural Products Chemistry Research Unit, Department of Chemistry, Faculty of Sciences, University of Dschang, Dschang, CameroonView further author information
,
Regina Appiah-Opongd Department of Clinical Pathology, Noguchi Memorial Institute for Medical Research (NMIMR), College of Health Sciences (CHS), University of Ghana, Accra, GhanaView further author information
&
Gabriel Agbor Agbora Centre for Research on Medicinal Plants and Traditional Medicine, Institute of Medical Research and Medicinal Plants Studies, Yaoundé, CameroonView further author information
 show all
Pages 2935-2939 | Received 17 Jun 2022, Accepted 14 Oct 2022, Published online: 25 Oct 2022

References

  • De Muylder G, Ang KK, Chen S, Arkin IR, Engel JC, McKerrow JH. 2011. A screen against leishmania intracellular amastigotes: comparison to a promastigote screen and identification of a Host Cell-Specific Hit. PLoS Negl Trop Dis. 5(7):e1253.
  • Fassil Y, Bezabeh A, Abegaz B, Botta B, Monache GD, Monache FD. 1985. Anthracene derivatives from Rumex abyssinicus. J Nat Prod. 48(1):148–148.
  • Ferede G, Diro E, Getie S, Getnet G, Takele Y, Amsalu A, Wondimeneh Y. 2017. Visceral Leishmaniasis-Malaria co-infection and their associated factors in patients attending Metema Hospital, Northwest Ethiopia: suggestion for integrated vector management. Malar Res Treat.:2017:6816913.
  • Ghoneim MM, Ma G, El-Hela AA, Mohammad AI, Kottob S, El-Ghaly SJ, Cutler SJ, Rossa S. 2013. Biologically active secondary metabolites from Asphodelus microcarpus. Nat Prod Comm. 8:1117–1119.
  • Ilgoutz SC, McConville MJ. 2001. Function and assembly of Leishmania surface coat. Int J Parasitol. 31(9):899–908.
  • Kima PE. 2007. The amastigote forms of Leismania are experts at exploiting host cell processes to establish infection and persist. Int J Parasitol. 37(10):1087–1096.
  • Lal UR, Singh A. 2016. Recent developments in natural product-based drug discovery in tropical diseases studies. Nat Prod Chem. 48:263–285.
  • Lee CY, Nanah C, Held R, Clark A, Huynh U, Maraskine MC, Uzarski RL, McCracken J, Sharma A. 2015. Effect of electron donating groups on polyphenol-based antioxidant dendrimers. Biochimie. 111:125–134.
  • Mbwambo ZH, Apers S, Moshi MJ, Kapingu MC, Van Miert S, Claeys M, Brun R, Cos P, Pieters L, Vlietinck A. 2004. Anthranoid compounds with antiprotozoal activity from Vismia orientalis. Planta Med. 70(8):706–710.
  • Mekonnen T, Urga K, Engidawork E. 2010. Evaluation of the diuretic and analgesic activities of the rhizomes of Rumex abyssinicus Jacq in mice. J Ethnopharmacol. 127(2):433–439.
  • Muganga R, Angenot L, Tits M, Frédérich M. 2010. Antiplasmodial and cytotoxic activities of Rwandan medicinal plants used in the treatment of malaria. J Ethnopharmacol. 128(1):52–57.
  • Mulisa E, Asres K, Engidawork E. 2015. Evaluation of wound healing and anti-inflammatory activity of the rhizomes of Rumex abyssinicus J. (Polygonaceae) in mice. BMC Complement Altern Med. 15:341.
  • Munavu R, Mudamba L, Ogur J. 1984. Isolation and characterization of the Major anthraquinone pigments from Rumex abysinica. Planta Med. 50(1):111.
  • Na MK, Jin WY, Min BS, Ahn JS, Bae K. 2008. Protein tyrosine phosphate 1B inhibitory activity of anthraquinones qnd stilbenes. Nat Prod Sci. 14:143–146.
  • Newman DJ, Cragg GM. 2020. Natural products as sources of new drugs over the nearly four decades from 01/1981 to 09/2019. J Nat Prod. 83(3):770–803.
  • Ntemafack A, Vijay KN, Abdullaha M, Hassan QP, Gandhi SG, Bharate SB. 2020. Discovery of Helminthosporin, an anthraquinone isolated from Rumex abyssinicus Jacq as a Dual cholinesterase inhibitor. ACS Omega. 5:1616–1624.
  • Osman CP, Ismail NH, Widyawaruyanti A, Imran S, Tumewu L, Choo C-Y, Sharinah I. 2019. Evaluation of a series of 9,10-anthraquinones as antiplasmodial agents. Lett Drug Des Discov. 16(3):353–363.
  • St George S, Bishop JV, Richard G, Titus RG, Selitrennikoff CP. 2006. Novel compounds active against Leishmania major. Antimicrob Agents Chemother. 2:474–479.
  • Tala MF, Ansary MWR, Talontsi FM, Kowa TK, Tofazzal IM, Tane P. 2018. Anthraquinones and flavanols isolated from the vegetable herb Rumex abyssinicus inhibit motility of Phytophthora capsici zoospores. S Afr J Bot. 115:1–4.
  • Tewabe Y, Kefarge B, Belay H, Bisrat D, Asrat H, Asres K. 2019. Antileishmanial evaluation of the leaf latex of Aloe macrocarpa, Aloin A/B, and its semisynthetic derivatives against two Leishmania species. Evid-Based Complement Altern Med.:2019:4736181.
  • Tsamo LDF, Yimgang LV, Wouamba SCN, Mkounga P, Nkengfack AE, Voutquenne-Nazabadioko L, Ngnokam D, Lenta BN, Sewald N. 2021. A new ceramide (Rumexamide) and other chemical constituents from Rumex abyssinicus Jacq (Polygonaceae): isolation, characterization, antibacterial activities and chemophenetic significance. Adv Biol Chem. 11(05):266–282.
  • WHO. 2021. Leishmaniasis key facts. Available from: https://www.who.int/news-room/fact-sheets/detail/leishmaniasis. consulted on 05/01/2022 at 11h31
  • Winter RW, Cornell KA, Johnson LL, Isabelle LM, Hinrichs DJ, Riscoe MK. 1995. Hydroxy-anthraquinones as antimalarial agents. Bioorg Med Chem Lett. 5(17):1927–1932.
  • Worku N, Mossie A, Stich A, Daugschies A, Trettner S, Hemdan NYA, Birkenmeier G. 2013. Evaluation of the in vitro efficacy of Artemisia annua, Rumex abyssinicus, and Catha edulis Forsk extracts in cancer and Trypanosoma brucei cells. ISRN Biochem. 2013:910308–910310.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.