Steady state plasma and tissue distribution of low molecular weight hyaluronic acid after oral administration in mice

References

• Aragona P, Papa V, Micali A, Santocono M, Milazzo G. 2002. Long term treatment with sodium hyaluronate-containing artificial tears reduces ocular surface damage in patients with dry eye. Br J Ophthalmol. 86(2):181–184. PMID: 11815344; PMCID: PMC1771021.
   PubMed Web of Science ®Google Scholar
• Balogh L, Polyak A, Mathe D, Kiraly R, Thuroczy J, Terez M, Janoki G, Ting Y, Bucci LR, Schauss AG. 2008. Absorption, uptake, and tissue affinity of high-molecular-weight hyaluronan after oral administration in rats and dogs. J Agric Food Chem. 56(22):10582–10593. PMID: 18959406.
   PubMed Web of Science ®Google Scholar
• Battaglia M, Guaraldi F, Vannini F, Rossi G, Timoncini A, Buda R, Giannini S. 2013. Efficacy of ultrasound-guided intra-articular injections of platelet-rich plasma versus hyaluronic acid for hip osteoarthritis. Orthopedics. 36(12):e1501–e1508. PMID: 24579221.
   PubMed Web of Science ®Google Scholar
• Bray BA. 2001. The role of hyaluronan in the pulmonary alveolus. J Theor Biol. 210(1):121–130. PMID: 11343436.
   PubMed Web of Science ®Google Scholar
• Chang E-J, Kim HJ, Ha J, Kim HJ, Ryu J, Park K-H, Kim U-H, Lee ZH, Kim H-M, Fisher DE, et al. 2007. Hyaluronan inhibits osteoclast differentiation via Toll-like receptor 4. J Cell Sci. 120(Pt 1):166–176.
   PubMed Web of Science ®Google Scholar
• Ciofalo A, Zambetti G, Altissimi G, Fusconi M, Soldo P, Gelardi M, Iannella G, Pasquariello B, Magliulo G. 2017. Pathological and cytological changes of the nasal mucosa in acute rhinosinusitis: the role of hyaluronic acid as supportive therapy. Eur Rev Med Pharmacol Sci. 21(19):4411–4418. PMID: 29077152.
   PubMed Web of Science ®Google Scholar
• Costantino D, Guaraldi C. 2008. Effectiveness, and safety of vaginal suppositories for the treatment of the vaginal atrophy in postmenopausal women: an open, non-controlled clinical trial. Eur Rev Med Pharmacol Sci. 22(6):411–6.
   Google Scholar
• Cyphert JM, Trempus CS, Garantziotis S. 2015. Size matters: molecular weight specificity of hyaluronan effects in cell biology. Int J Cell Biol. 2015:563818. Epub 2015 Sep 10. PMID: 26448754; PMCID: PMC4581549.
   PubMedGoogle Scholar
• Essendoubi M, Gobinet C, Reynaud R, Angiboust JF, Manfait M, Piot O. 2016. Human skin penetration of hyaluronic acid of different molecular weights as probed by Raman spectroscopy. Skin Res Technol. 22(1):55–62.
   PubMed Web of Science ®Google Scholar
• Fraser JR, Laurent TC, Laurent UB. 1997. Hyaluronan: its nature, distribution, functions and turnover. J Intern Med. 242(1):27–33. PMID: 9260563.
   PubMed Web of Science ®Google Scholar
• Gao F, Yang CX, Mo W, Liu YW, He YQ. 2008. Hyaluronan oligosaccharides are potential stimulators to angiogenesis via RHAMM mediated signal pathway in wound healing. Clin Invest Med. 31(3):E106–16.
   PubMed Web of Science ®Google Scholar
• Gariboldi S, Palazzo M, Zanobbio L, Selleri S, Sommariva M, Sfondrini L, Cavicchini S, Balsari A, Rumio C. 2008. Low molecular weight hyaluronic acid increases the self-defense of skin epithelium by induction of beta-defensin 2 via TLR2 and TLR4. J Immunol. 181(3):2103–2110.
   PubMed Web of Science ®Google Scholar
• Göllner I, Voss W, von Hehn U, Kammerer S. 2017. Ingestion of an oral hyaluronan solution improves skin hydration, wrinkle reduction, elasticity, and skin roughness: results of a clinical study. J Evid Based Complementary Altern Med. 22(4):816–823. Epub 2017 Dec 4. PMID: 29228816; PMCID: PMC5871318.
   PubMedGoogle Scholar
• Gomes JA, Amankwah R, Powell-Richards A, Dua HS. 2004. Sodium hyaluronate (hyaluronic acid) promotes migration of human corneal epithelial cells in vitro. Br J Ophthalmol. 88(6):821–825. PMID: 15148219; PMCID: PMC1772195.
   PubMed Web of Science ®Google Scholar
• Heldin P, Lin CY, Kolliopoulos C, Chen YH, Skandalis SS. 2019. Regulation of hyaluronan biosynthesis and clinical impact of excessive hyaluronan production. Matrix Biol. 78–79:100–117. Epub 2018 Jan 31. PMID: 29374576.
   PubMed Web of Science ®Google Scholar
• Hisada N, Satsu H, Mori A, Totsuka M, Kamei J, Nozawa T, Shimizu M. 2008. Low-molecular-weight hyaluronan permeates through human intestinal Caco-2 cell monolayers via the paracellular pathway. Biosci Biotechnol Biochem. 72(4):1111–1114. Epub 2008 Apr 7. PMID: 18391466.
   PubMed Web of Science ®Google Scholar
• Homayun B, Lin X, Choi HJ. 2019. Challenges and recent progress in oral drug delivery systems for biopharmaceuticals. Pharmaceutics. 11(3):129. PMID: 30893852; PMCID: PMC6471246.
   PubMed Web of Science ®Google Scholar
• Huynh A, Priefer R. 2020. Hyaluronic acid applications in ophthalmology, rheumatology, and dermatology. Carbohydr Res. 489:107950. Epub 2020 Feb 18. PMID: 32070808.
   PubMed Web of Science ®Google Scholar
• Jensen GS, Attridge VL, Lenninger MR, Benson KF. 2015. Oral intake of a liquid high-molecular-weight hyaluronan associated with relief of chronic pain and reduced use of pain medication: results of a randomized, placebo-controlled double-blind pilot study. J Med Food. 18(1):95–101. PMID: 25415767; PMCID: PMC4281855.
   PubMed Web of Science ®Google Scholar
• Jiang D, Liang J, Noble PW. 2011. Hyaluronan as an immune regulator in human diseases. Physiol Rev. 91(1):221–264. PMID: 21248167; PMCID: PMC3051404.
   PubMed Web of Science ®Google Scholar
• Kavasi R-M, Berdiaki A, Spyridaki I, Corsini E, Tsatsakis A, Tzanakakis G, Nikitovic D. 2017. HA metabolism in skin homeostasis and inflammatory disease. Food Chem Toxicol. 101:128–138. Mar
   PubMed Web of Science ®Google Scholar
• Kilkenny C, Browne W, Cuthill IC, Emerson M, Altman DG. 2010. Animal research: reporting in vivo experiments: the ARRIVE guidelines. Br J Pharmacol. 160(7):1577–1579.
   PubMed Web of Science ®Google Scholar
• Kimura M, Maeshima T, Kubota T, Kurihara H, Masuda Y, Nomura Y. 2016. Absorption of orally administered hyaluronan. J Med Food. 19(12):1172–1179. PMID: 27982756.
   PubMed Web of Science ®Google Scholar
• Komatsu S, Iwata H, Nabeshima T. 1999. Studies on the kinetics, metabolism and re-utilisation after intra-articular administration of hyaluronan to rabbits. Arzneimittelforschung. 49(5):427–433.
   PubMed Web of Science ®Google Scholar
• La Galia T, Micali A, Puzzolo D, Cancellieri F. 2014. Oral low-molecular weight hyaluronic acid in the treatment of atrophic vaginitis. Indian J Community Med. 5(11):617–624.
   Google Scholar
• Laurent UBG, Dahl LB, Reed RK. 1991. Catabolism of hyaluronan in rabbit skin takes place locally in lymph nodes and liver. Exp Physiol. 76(5):695–703.
   PubMed Web of Science ®Google Scholar
• Leal J, Smyth HDC, Ghosh D. 2017. Physicochemical properties of mucus and their impact on transmucosal drug delivery. Int J Pharm. 532(1):555–572.
   PubMed Web of Science ®Google Scholar
• Lipko-Godlewska S, Bolanča Ž, Kalinová L, Kermen I, Onisak B, Papp I, Rebrov M, Valančienė G. 2021. Whole-face approach with hyaluronic acid fillers. Clin Cosmet Investig Dermatol. 14:169–178. PMID: 33633459; PMCID: PMC7901566.
   PubMed Web of Science ®Google Scholar
• Nakamura K, Yokohama S, Yoneda M, Okamoto S, Tamaki Y, Ito T, Okada M, Aso K, Makino I. 2004. High, but not low, molecular weight hyaluronan prevents T-cell-mediated liver injury by reducing proinflammatory cytokines in mice. J Gastroenterol. 39(4):346–354.
   PubMed Web of Science ®Google Scholar
• Nolan A, Baillie C, Badminton J, Rudralingham M, Seymour RA. 2006. The efficacy of topical hyaluronic acid in the management of recurrent aphthous ulceration. J Oral Pathol Med. 35(8):461–465. PMID: 16918596.
   PubMed Web of Science ®Google Scholar
• Piro F, Marafioti L. 2018. Oral low molecular weight hyaluronic acid in the prevention and treatment of radiation-induced cystitis. IJMDAT. 1(1):e112.
   Google Scholar
• Sato T, Sakamoto W, Odanaka W. 2002. Clinical effect of hyaluronic acid diet for dry and rough skin. Aesthetic Dermatol. 12:109–120.
   Google Scholar
• Tamer TM. 2013. Hyaluronan and synovial joint: function, distribution, and healing. Interdiscip Toxicol. 6(3):111–125. PMID: 24678248; PMCID: PMC3967437.
   PubMedGoogle Scholar
• Valachová K, Šoltés L. 2021. Hyaluronan as a prominent biomolecule with numerous applications in medicine. Int J Mol Sci. 22(13):7077. PMID: 34209222; PMCID: PMC8269271.
   PubMed Web of Science ®Google Scholar
• Vasvani S, Kulkarni P, Rawtani D. 2020. Hyaluronic acid: a review on its biology, aspects of drug delivery, route of administrations and a special emphasis on its approved marketed products and recent clinical studies. Int J Biol Macromol. 151:1012–1029. Epub 2019 Nov 9. PMID: 31715233.
   PubMed Web of Science ®Google Scholar