420
Views
5
CrossRef citations to date
0
Altmetric
Review

The challenge of curbing aminoglycoside resistance: can antimicrobial stewardship programs play a critical role?

, , &
Pages 947-954 | Received 16 Jul 2017, Accepted 18 Sep 2017, Published online: 25 Sep 2017

References

  • Gilbert DN. Aminoglycosides. In: Mandell GL, Bennett JE, Dolin R, Eds. Principles and practice of infectious diseases. 6th ed. New York: Churchill Livingstone; 2005. p. 328.
  • Haldorsen BC, Simonsen GS, Sundsfjord A, et al. Norwegian Study Group on aminoglycoside resistance. Increased prevalence of aminoglycoside resistance in clinical isolates of Escherichia coli and Klebsiella spp. in Norway is associated with the acquisition of AAC(3)-II and AAC(6ʹ)-Ib. Diagn Microbiol Infect Dis. 2014;78(1):66–69.
  • Labby KJ, Garneau-Tsodikova S. Strategies to overcome the action of aminoglycoside-modifying enzymes for treating resistant bacterial infections. Future Med Chem. 2013;5:1285–1309.
  • Dellit TH, Owens RC, McGowan JE, et al. Infectious Diseases Society of America and the Society For Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship. Clin Infect Dis. 2007;44:159–177.
  • MacDougall C, Polk RE. Antimicrobial stewardship programs in health care systems. Clin Microbiol Rev. 2005;18:638–656.
  • Owens RC Jr. Antimicrobial stewardship: concepts and strategies in the 21st century. Diagn Microbiol Infect Dis. 2008;61:110–128.
  • Vidal L, Gafter-Gvili A, Borok S, et al. Efficacy and safety of aminoglycoside monotherapy: systematic review and meta-analysis of randomized controlled trials. J Antimicrob Chemother. 2007;60:247–257.
  • Lopez-Novoa JM, Quiros Y, Vicente L, et al. New insights into the mechanism of aminoglycoside nephrotoxicity: an integrative point of view. Kidney Int. 2011;79:33–45.
  • Pakyz AL, MacDougall C, Oinonen M, et al. Trends in antibacterial use in US academic health centers: 2002–2006. Arch Intern Med. 2008;168:2254–2260.
  • Leibovici L, Vidal L, Paul M. Aminoglycoside drugs in clinical practice: an evidence-based approach. J Antimicrob Chemother. 2009;63:246–251.
  • Mueller EW, Boucher BA. The use of extended-interval aminoglycoside dosing strategies for the treatment of moderate-to-severe infections encountered in critically ill surgical patients. Surg Infect. 2009;10:563–570.
  • Gerding DN. Antimicrobial cycling: lessons learned from the aminoglycoside experience. Infect Control Hosp Epidemiol. 2000;21:S12–7.
  • Brown EM, Nathwani D. Antibiotic cycling or rotation: a systematic review of the evidence of efficacy. J Antimicrob Chemother. 2005;55:6–9.
  • Bennett KM, Scarborough JE, Sharpe M, et al. Implementation of antibiotic rotation protocol improves antibiotic susceptibility profile in a surgical intensive care unit. J Trauma. 2007;63:307–311.
  • Gerding DN, Larson TA. Aminoglycoside resistance in gram-negative bacilli during increased amikacin use. Comparison of experience in 14 United States hospitals with experience in the Minneapolis Veterans Administration Medical Center. Am J Med. 1985;79:1–7.
  • Young EJ, Sewell CM, Koza MA, et al. Antibiotic resistance patterns during aminoglycoside restriction. Am J Med Sci. 1985;290:223–227.
  • Saavedra S, Vera D, Ramírez-Ronda CH. Susceptibility of aerobic gram-negative bacilli to aminoglycosides. Effects of 45 months of amikacin as first-line aminoglycoside therapy. Am J Med. 1986;80:65–70.
  • Betts RF, Valenti WM, Chapman SW, et al. Five-year surveillance of aminoglycoside usage in a university hospital. Ann Intern Med. 1984;100:219–222.
  • Berk SL, Alvarez S, Ortega G, et al. Clinical and microbiologic consequences of amikacin use during a 42-month period. Arch Intern Med. 1986;146:538–541.
  • Francetić I, Smilja K, Mirjana H, et al. Impact of aminoglycoside cycling in six tertiary intensive care units – prospective longitudinal interventional study. Croat Med J. 2008;49:207–214.
  • Friedland IR, Funk E, Khoosal M, et al. Increased resistance to amikacin in a neonatal unit following intensive amikacin usage. Antimicrob Agents Chemother. 1992;36:1596–1600.
  • Bosso JA, Haines ML, Gomez J. Stable susceptibility to aminoglycosides in an age of low level, institutional use. Infect Dis Ther. 2013;2:209–215.
  • Yong MK, Buising KL, Cheng AC, et al. Improved susceptibility of Gram-negative bacteria in an intensive care unit following implementation of a computerized antibiotic decision support system. J Antimicrob Chemother. 2010;65:1062–1069.
  • Zhang ZG, Chen F, Ou Y. Impact of an antimicrobial stewardship programme on antibiotic usage and resistance in a tertiary hospital in China. J Clin Pharm Ther. 2017. DOI:10.1111/jcpt.12544.
  • Hou D, Wang Q, Jiang C, et al. Evaluation of the short-term effects of antimicrobial stewardship in the intensive care unit at a tertiary hospital in China. PLoSOne. 2014;9:e101447.
  • Niwa T, Shinoda Y, Suzuki A, et al. Outcome measurement of extensive implementation of antimicrobial stewardship in patients receiving intravenous antibiotics in a Japanese university hospital. Int J Clin Pract. 2012;66:999–1008.
  • Zou YM, Ma Y, Liu JH, et al. Trends and correlation of antibacterial usage and bacterial resistance: time series analysis for antibacterial stewardship in a Chinese teaching hospital (2009-2013). Eur J Clin Microbiol Infect Dis. 2015;34:795–803.
  • Timbrook TT, Hurst JM, Bosso JA. Impact of an antimicrobial stewardship program on antimicrobial utilization, bacterial susceptibilities, and financial expenditures at an academic medical center. Hosp Pharm. 2016;51:703–711.
  • Slain D, Sarwari AR, Petros KO, et al. Impact of a multimodal antimicrobial stewardship program on pseudomonas aeruginosa susceptibility and antimicrobial use in the intensive care unit setting. Crit Care Res Pract. 2011;416426. DOI:10.1155/2011/416426.
  • Ababneh M, Harpe S, Oinonen M, et al. Trends in aminoglycoside use and gentamicin-resistant gram-negative clinical isolates in US academic medical centers: implications for antimicrobial stewardship. Infect Control Hosp Epidemiol. 2012;33:594–601.10.1086/665724.
  • Lortholary O, Tod M, Cohen Y, et al. Aminoglycosides. Med Clin North Am. 1995;79:761–787.
  • Paul M, Dickstein Y, Schlesinger A, et al. Beta-lactam versus beta-lactam-aminoglycoside combination therapy in cancer patients with neutropenia. Cochrane Database Syst Rev. 2013;29:CD003038. DOI:10.1002/14651858.CD003038.pub2.
  • Tamma PD, Cosgrove SE, Maragakis LL. Combination therapy for treatment of infections with gram-negative bacteria. Clin Microbiol Rev. 2012;25:450–470.
  • May AK. An argument for the use of aminoglycosides in the empiric treatment of ventilator-associated pneumonia. Surg Infect (Larchmt). 2016;17(3):329–333.
  • Boucher HW, Talbot GH, Benjamin DK Jr, et al. 10 x ‘20 progress–development of new drugs active against gram-negative bacilli: an update from the Infectious Diseases Society of America. Clin Infect Dis. 2013;56:1685–1694.
  • Endimiani A, Paterson DL. Optimizing therapy for infections caused by Enterobacteriaceae producing extended-spectrum beta-lactamases. Semin Respir Crit Care Med. 2007;28:646–655.
  • Kasiakou SK, Lawrence KR, Choulis N, et al. Continuous versus intermittent intravenous administration of antibacterials with time-dependent action: a systematic review of pharmacokinetic and pharmacodynamic parameters. Drugs. 2005;65:2499–2511.
  • Dubé J, Caillon C, Jacqueline D, et al. The optimal aminoglycoside and its dosage for the treatment of severe Enterococcus faecalis infection. An experimental study in the rabbit endocarditis model. Eur J Clin Microbiol Infect Dis. 2012;31:2545–2547.
  • Drusano GL, Louie A. Optimization of aminoglycoside therapy. Antimicrob Agents Chemother. 2011;55:2528–2531. DOI:10.1128/AAC.01314-10.
  • Udy AA, Roberts JA, Boots RJ, et al. Augmented renal clearance: implications for antibacterial dosing in the critically ill. Clin Pharmacokinet. 2010;49:1–16.
  • Rea RS, Capitano B, Bies R, et al. Suboptimal aminoglycoside dosing in critically ill patients. Ther Drug Monit. 2008;30:674–681.
  • Stankowicz MS, Ibrahim J, Brown DL. Once-daily aminoglycoside dosing: an update on current literature. Am J Health Syst Pharm. 2015;72:1357–1364.
  • Moore RD, Smith CR, Lietman PS. Association of aminoglycoside plasma levels with therapeutic outcome in Gram-negative pneumonia. Am J Med. 1984;77:657–662.
  • Torfoss D, Hoiby EA, Tangen JM, et al. Tobramycin once versus three times daily, given with penicillin G, to febrile neutropenic cancer patients in Norway: a prospective, randomized, multicentre trial. J Antimicrob Chemother. 2007;59:711–717.
  • Swan SK. Aminoglycoside nephrotoxicity. Semin Nephrol. 1997;17:27–33.
  • Croes S, Koop AH, van Gils SA, et al. Nephrotoxicity and ototoxicity of aminoglycosides, mathematically modelled for modelling-supported therapeutic drug monitoring. Eur J Pharm Sci. 2012;45;23:90–100.
  • Nicolau DP, Freeman CD, Belliveau PP, et al. Experience with a once-daily aminoglycoside program administered to 2,184 adult patients. Antimicrob Agents Chemother. 1995;39:650–655.
  • Sánchez-Alcaraz A, Vargas A, Quintana MB, et al. Therapeutic drug monitoring of tobramycin: once-daily versus twice-daily dosage schedules. J Clin Pharm Ther. 1998;23:367–373.
  • Barclay ML, Kirkpatrick CM, Begg EJ. Once daily aminoglycoside therapy. Is it less toxic than multiple daily doses and how should it be monitored? Clin Pharmacokinet. 1999;36:89–98.
  • Smits A, Kulo A, van den Anker J, et al. The amikacin research program: a stepwise approach to validate dosing regimens in neonates. Expert Opin Drug Metab Toxicol. 2017;13:157–166.
  • Abdel-Hady E, El Hamamsy M, Hedaya M, et al. The efficacy and toxicity of two dosing-regimens of amikacin in neonates with sepsis. J Clin Pharm Ther. 2011;36:45–52.
  • Nezic L, Derungs A, Bruggisser M, et al. Therapeutic drug monitoring of once daily aminoglycoside dosing: comparison of two methods and investigation of the optimal blood sampling strategy. Eur J Clin Pharmacol. 2014 Jul; 70(7):829–837. DOI:10.1007/s00228-014-1680-3.
  • Roberts JA, Norris R, Paterson DL, et al. Therapeutic drug monitoring of antimicrobials. Br J Clin Pharmacol. 2012;73:27–36.
  • Drusano GL, Ambrose PG, Bhavnani SM, et al. Back to the future: using aminoglycosides again and how to dose them optimally. Clin Infect Dis. 2007;45:753–760.
  • Barras MA, Serisier D, Hennig S, et al. Bayesian Estimation of tobramycin exposure in patients with cystic fibrosis. Antimicrob Agents Chemother. 2016;60:6698–6702.
  • Singhal N, Kumar M, Kanaujia PK, et al. MALDI-TOF mass spectrometry: an emerging technology for microbial identification and diagnosis. Front Microbiol. 2015;6:791.
  • Clinical laboratory testing and in vitro diagnostic test systems — Susceptibility testing of infectious agents and evaluation of performance of antimicrobial susceptibility test devices — Part 1: Reference method for testing the in vitro activity of antimicrobial agents against rapidly growing aerobic bacteria involved in infectious diseases. https://www.iso.org/standard/41630.html

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.