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Review

Diagnostic imaging in infective endocarditis: a contemporary perspective

, , , , ORCID Icon &
Pages 911-925 | Received 01 Jan 2020, Accepted 20 May 2020, Published online: 09 Jun 2020

References

  • Habib G, Erba PA, Iung B, et al. Clinical presentation, aetiology and outcome of infective endocarditis. Results of the ESC-EORP EURO-ENDO (European Infective Endocarditis) registry: a prospective cohort study. Eur Heart J. 2019 Oct 14;40(39):3222–3232.
  • Li JS, Sexton DJ, Mick N, et al. Proposed modifications to the Duke criteria for the diagnosis of infective endocarditis. Clin Infect Dis. 2000 Apr;30(4):633–638.
  • Habib G, Lancellotti P, Antunes MJ, et al. 2015 ESC guidelines for the management of infective endocarditis: the task force for the management of infective endocarditis of the European Society of Cardiology (ESC). Endorsed by: European Association for Cardio-Thoracic Surgery (EACTS), the European Association of Nuclear Medicine (EANM). Eur Heart J. 2015 Nov 21;36(44):3075–3128.
  • Harrison JL, Prendergast BD, Habib G. The European Society of Cardiology 2009 guidelines on the prevention, diagnosis, and treatment of infective endocarditis: key messages for clinical practice. Polskie Archiwum Medycyny Wewnetrznej. 2009 Dec;119(12):773–776.
  • Mgbojikwe N, Jones SR, Leucker TM, et al. Infective endocarditis: beyond the usual tests. Cleve Clin J Med. 2019 Aug;86(8):559–567.
  • Gomes A, Glaudemans A, Touw DJ, et al. Diagnostic value of imaging in infective endocarditis: a systematic review. Lancet Infect Dis. 2017 Jan;17(1):e1–e14.
  • Min JK, Spencer KT, Furlong KT, et al. Clinical features of complications from transesophageal echocardiography: a single-center case series of 10,000 consecutive examinations. J Am Soc Echocardiog. 2005 Sep;18(9):925–929.
  • Cote G, Denault A. Transesophageal echocardiography-related complications. Can J Anaesth. 2008 Sep;55(9):622–647.
  • Feuchtner GM, Stolzmann P, Dichtl W, et al. Multislice computed tomography in infective endocarditis: comparison with transesophageal echocardiography and intraoperative findings. J Am Coll Cardiol. 2009 Feb 3;53(5):436–444.
  • Del Prado Diaz S, Refoyo Salicio E, Valbuena-Lopez SC, et al. Multidetector computed tomography usefulness in infective endocarditis. Rev Esp Cardiol (Engl Ed). 2016 Apr;69(4):442–445.
  • Fagman E, Flinck A, Snygg-Martin U, et al. Surgical decision-making in aortic prosthetic valve endocarditis: the influence of electrocardiogram-gated computed tomography. Eur J Cardio-thorac Surg. 2016 Dec;50(6):1165–1171.
  • Fagman E, Perrotta S, Bech-Hanssen O, et al. ECG-gated computed tomography: a new role for patients with suspected aortic prosthetic valve endocarditis. Eur Radiol. 2012 Nov;22(11):2407–2414.
  • Bomanji JB, Costa DC, Ell PJ. Clinical role of positron emission tomography in oncology. Lancet Oncol. 2001 Mar;2(3):157–164.
  • Blodgett TM, Meltzer CC, Townsend DW. PET/CT: form and function. Radiology. 2007 Feb;242(2):360–385.
  • Baddour LM, Wilson WR, Bayer AS, et al. Infective endocarditis in adults: diagnosis, antimicrobial therapy, and management of complications: a scientific statement for healthcare professionals from the American Heart Association. Circulation. 2015 Oct 13;132(15):1435–1486.
  • Bai AD, Steinberg M, Showler A, et al. Diagnostic accuracy of transthoracic echocardiography for infective endocarditis findings using transesophageal echocardiography as the reference standard: a meta-analysis. J Am Soc Echocardiography. 2017 Jul;30(7):639–646.e8.
  • Evangelista A, Gonzalez-Alujas MT. Echocardiography in infective endocarditis. Heart. 2004 Jun;90(6):614–617.
  • Habib G, Badano L, Tribouilloy C, et al. Recommendations for the practice of echocardiography in infective endocarditis. Eur J Echocardiogr. 2010 Mar;11(2):202–219.
  • San Roman JA, Vilacosta I, Zamorano JL, et al. Transesophageal echocardiography in right-sided endocarditis. J Am Coll Cardiol. 1993 Apr;21(5):1226–1230.
  • Le KY, Sohail MR, Friedman PA, et al. Clinical predictors of cardiovascular implantable electronic device-related infective endocarditis. Pacing Clin Electrophysiol. 2011 Apr;34(4):450–459.
  • San Roman JA, Vilacosta I, Lopez J, et al. Role of transthoracic and transesophageal echocardiography in right-sided endocarditis: one echocardiographic modality does not fit all. J Am Soc Echocardiography. 2012 Aug;25(8):807–814.
  • Law A, Honos G, Huynh T. Negative predictive value of multiplane transesophageal echocardiography in the diagnosis of infective endocarditis. Eur J Echocardiogr. 2004 Dec;5(6):416–421.
  • Hansalia S, Biswas M, Dutta R, et al. The value of live/real time three-dimensional transesophageal echocardiography in the assessment of valvular vegetations. Echocardiography. 2009 Nov;26(10):1264–1273.
  • Thompson KA, Shiota T, Tolstrup K, et al. Utility of three-dimensional transesophageal echocardiography in the diagnosis of valvular perforations. Am J Cardiol. 2011 Jan;107(1):100–102.
  • Heiro M, Helenius H, Hurme S, et al. Long-term outcome of infective endocarditis: a study on patients surviving over one year after the initial episode treated in a Finnish teaching hospital during 25 years. BMC Infect Dis. 2008 Apr 17;8:49.
  • Maruyama T, Takada M, Hasuike T, et al. Radiation dose reduction and coronary assessability of prospective electrocardiogram-gated computed tomography coronary angiography: comparison with retrospective electrocardiogram-gated helical scan. J Am Coll Cardiol. 2008 Oct 28;52(18):1450–1455.
  • Shuman WP, Branch KR, May JM, et al. Prospective versus retrospective ECG gating for 64-detector CT of the coronary arteries: comparison of image quality and patient radiation dose. Radiology. 2008 Aug;248(2):431–437.
  • Hsieh J, Londt J, Vass M, et al. Step-and-shoot data acquisition and reconstruction for cardiac x-ray computed tomography. Med Phys. 2006 Nov;33(11):4236–4248.
  • Gomes A, van Geel PP, Santing M, et al. Imaging infective endocarditis: adherence to a diagnostic flowchart and direct comparison of imaging techniques. J Nucl Cardiol. 2018 Jul 31;27(2):592-608.
  • Casas EA, Nunez VP, Pasin MDP, et al. Advantages and limitations of 18-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography in the diagnosis of infective endocarditis. Rev Portuguesa Cardiol. 2019 Aug;38(8):573–580.
  • Bonfiglioli R, Nanni C, Morigi JJ, et al. (1)(8)F-FDG PET/CT diagnosis of unexpected extracardiac septic embolisms in patients with suspected cardiac endocarditis. Eur J Nucl Med Mol Imaging. 2013 Aug;40(8):1190–1196.
  • Asmar A, Ozcan C, Diederichsen AC, et al. Clinical impact of 18F-FDG-PET/CT in the extra cardiac work-up of patients with infective endocarditis. Eur Heart J Cardiovasc Imaging. 2014 Sep;15(9):1013–1019.
  • Scholtens AM, Swart LE, Verberne HJ, et al. Confounders in FDG-PET/CT imaging of suspected prosthetic valve endocarditis. JACC Cardiovasc Imaging. 2016 Dec;9(12):1462–1465.
  • Orvin K, Goldberg E, Bernstine H, et al. The role of FDG-PET/CT imaging in early detection of extra-cardiac complications of infective endocarditis. Clin Microbiol Infect. 2015 Jan;21(1):69–76.
  • Salomaki SP, Saraste A, Kemppainen J, et al. (18)F-FDG positron emission tomography/computed tomography in infective endocarditis. J Nucl Cardiol. 2017 Feb;24(1):195–206.
  • Boellaard R, Delgado-Bolton R, Oyen WJ, et al. FDG PET/CT: EANM procedure guidelines for tumour imaging: version 2.0. Eur J Nucl Med Mol Imaging. 2015 Feb;42(2):328–354.
  • Dorbala S, Di Carli MF, Delbeke D, et al. SNMMI/ASNC/SCCT guideline for cardiac SPECT/CT and PET/CT 1.0. J Nucl Med. 2013 Aug;54(8):1485–1507.
  • Millar BC, Prendergast BD, Alavi A, et al. 18FDG-positron emission tomography (PET) has a role to play in the diagnosis and therapy of infective endocarditis and cardiac device infection. Int J Cardiol. 2013 Sep 1;167(5):1724–1736.
  • Leccisotti L, Perna F, Lago M, et al. Cardiovascular implantable electronic device infection: delayed vs standard FDG PET-CT imaging. J Nucl Cardiol. 2014 Jun;21(3):622–632.
  • Scholtens AM, Swart LE, Kolste HJT, et al. Standardized uptake values in FDG PET/CT for prosthetic heart valve endocarditis: a call for standardization. J Nucl Cardiol. 2018 Dec;25(6):2084–2091.
  • Dilsizian V, Bacharach SL, Beanlands RS, et al. ASNC imaging guidelines/SNMMI procedure standard for positron emission tomography (PET) nuclear cardiology procedures. J Nucl Cardiol. 2016 Oct;23(5):1187–1226.
  • Ghafarian P, Aghamiri SM, Ay MR, et al. Is metal artefact reduction mandatory in cardiac PET/CT imaging in the presence of pacemaker and implantable cardioverter defibrillator leads? Eur J Nucl Med Mol Imaging. 2011 Feb;38(2):252–262.
  • Rubeaux M, Doris MK, Alessio A, et al. Enhancing cardiac PET by motion correction techniques. Curr Cardiol Rep. 2017 Feb;19(2):14.
  • Roque A, Pizzi MN, Cuellar-Calabria H, et al. (18)F-FDG-PET/CT angiography for the diagnosis of infective endocarditis. Curr Cardiol Rep. 2017 Feb;19(2):15.
  • Sharma A. Positron emission tomography/computed tomography for diagnosis of prosthetic valve endocarditis. J Am Coll Cardiol. 2013 Aug 27;62(9):861.
  • Juneau D, Golfam M, Hazra S, et al. Molecular imaging for the diagnosis of infective endocarditis: a systematic literature review and meta-analysis. Int J Cardiol. 2018 Feb 15;253:183–188.
  • Erba PA, Conti U, Lazzeri E, et al. Added value of 99mTc-HMPAO-labeled leukocyte SPECT/CT in the characterization and management of patients with infectious endocarditis. J Nucl Med. 2012 Aug;53(8):1235–1243.
  • Glaudemans AW, Israel O, Slart RH. Pitfalls and limitations of radionuclide and hybrid imaging in infection and inflammation. Semin Nucl Med. 2015 Nov;45(6):500–512.
  • Caobelli F, Wollenweber T, Bavendiek U, et al. Simultaneous dual-isotope solid-state detector SPECT for improved tracking of white blood cells in suspected endocarditis. Eur Heart J. 2017 Feb 7;38(6):436–443.
  • Duval X, Iung B, Klein I, et al. Effect of early cerebral magnetic resonance imaging on clinical decisions in infective endocarditis: a prospective study. Ann Intern Med. 2010 Apr 20;152(8)::497–504, W175.
  • Snygg-Martin U, Gustafsson L, Rosengren L, et al. Cerebrovascular complications in patients with left-sided infective endocarditis are common: a prospective study using magnetic resonance imaging and neurochemical brain damage markers. Clin Infect Dis. 2008 Jul 1;47(1):23–30.
  • Chakraborty T, Scharf E, DeSimone D, et al. Variable significance of brain MRI findings in infective endocarditis and its effect on surgical decisions. Mayo Clin Proc. 2019 Jun;94(6):1024–1032.
  • Chakraborty T, Scharf E, Rabinstein AA, et al. Utility of brain magnetic resonance imaging in the surgical management of infective endocarditis. J Stroke Cerebrovasc Dis. 2017 Nov;26(11):2527–2535.
  • Caduff JH, Hernandez RJ, Ludomirsky A. MR visualization of aortic valve vegetations. J Comput Assist Tomogr. 1996 Jul-Aug;20(4):613–615.
  • Pollak Y, Comeau CR, Wolff SD. Staphylococcus aureus endocarditis of the aortic valve diagnosed on MR imaging. AJR Am J Roentgenol. 2002 Dec;179(6):1647.
  • Zatorska K, Michalowska I, Duchnowski P, et al. The usefulness of magnetic resonance imaging in the diagnosis of infectious endocarditis. J Heart Valve Dis. 2015 Nov;24(6):767–775.
  • Dursun M, Yilmaz S, Yilmaz E, et al. The utility of cardiac MRI in diagnosis of infective endocarditis: preliminary results. Diagn Interv Radiol. 2015 Jan-Feb;21(1):28–33.
  • Vongpatanasin W, Hillis LD, Lange RA. Prosthetic heart valves. N Engl J Med. 1996 Aug 8;335(6):407–416.
  • Ostergaard L, Valeur N, Ihlemann N, et al. Incidence of infective endocarditis among patients considered at high risk. Eur Heart J. 2018 Feb 14;39(7):623–629.
  • Lyons K, Bhamidipati K. Comparison of transthoracic and transoesophageal echocardiography in the diagnosis of infective endocarditis – a tertiary centre experience. Heart. 2017 Oct;103:A3–A3.
  • Erba PA, Pizzi MN, Roque A, et al. Multimodality imaging in infective endocarditis: an imaging team within the endocarditis team. Circulation. 2019 Nov 19;140(21):1753–1765.
  • Miranda WR, Connolly HM, Baddour LM, et al. Infective endocarditis following transcatheter aortic valve replacement: diagnostic yield of echocardiography and associated echo-Doppler findings. Int J Cardiol. 2018 Nov 15;271:392–395.
  • Mangner N, Woitek F, Haussig S, et al. Incidence, predictors, and outcome of patients developing infective endocarditis following transfemoral transcatheter aortic valve replacement. J Am Coll Cardiol. 2016 Jun 21;67(24):2907–2908.
  • Amat-Santos IJ, Ribeiro HB, Urena M, et al. Prosthetic valve endocarditis after transcatheter valve replacement: a systematic review. JACC Cardiovasc Interv. 2015 Feb;8(2):334–346.
  • Bjursten H, Rasmussen M, Nozohoor S, et al. Infective endocarditis after transcatheter aortic valve implantation: a nationwide study. Eur Heart J. 2019 Oct 14;40(39):3263–3269.
  • Puls M, Eiffert H, Hunlich M, et al. Prosthetic valve endocarditis after transcatheter aortic valve implantation: the incidence in a single-centre cohort and reflections on clinical, echocardiographic and prognostic features. EuroIntervention. 2013 Apr 22;8(12):1407–1418.
  • Salaun E, Sportouch L, Barral PA, et al. Diagnosis of infective endocarditis after TAVR: value of a multimodality imaging approach. JACC Cardiovasc Imaging. 2018 Jan;11(1):143–146.
  • Yong MS, Saxena P, Killu AM, et al. The preoperative evaluation of infective endocarditis via 3-dimensional transesophageal echocardiography. Tex Heart Inst J. 2015 Aug;42(4):372–376.
  • Sungur A, Hsiung MC, Meggo Quiroz LD, et al. The advantages of live/real time three-dimensional transesophageal echocardiography in the assessment of tricuspid valve infective endocarditis. Echocardiography. 2014 Nov;31(10):1293–1309.
  • Musci RL, Girasoli C, Fumarola F, et al. Three-dimensional transesophageal echocardiographic diagnosis of catheter endocarditis hidden in intracaval stent. J Cardiovasc Echogr. 2018 Apr-Jun;28(2):124–126.
  • Gonzalez YO, Ung R, Blackshear JL, et al. Three-dimensional echocardiography for diagnosis of transcatheter prosthetic aortic valve endocarditis. CASE (Phila). 2017 Aug;1(4):155–158.
  • Habets J, Tanis W, van Herwerden LA, et al. Cardiac computed tomography angiography results in diagnostic and therapeutic change in prosthetic heart valve endocarditis. Int J Cardiovasc Imaging. 2014 Feb;30(2):377–387.
  • Kim IC, Chang S, Hong GR, et al. Comparison of cardiac computed tomography with transesophageal echocardiography for identifying vegetation and intracardiac complications in patients with infective endocarditis in the era of 3-dimensional images. Circ Cardiovasc Imaging. 2018 Mar;11(3):e006986.
  • Lancellotti P, Habib G, Oury C, et al. Positron emission tomography/computed tomography imaging in device infective endocarditis: ready for prime time. Circulation. 2015 Sep 22;132(12):1076–1080.
  • Wahadat AR, Tanis W, Swart LE, et al. Added value of (18)F-FDG-PET/CT and cardiac CTA in suspected transcatheter aortic valve endocarditis. J Nucl Cardiol. 2019 Dec 2. DOI:10.1007/s12350-019-01963-x.
  • Sucha D, Chamuleau SA, Symersky P, et al. Baseline MDCT findings after prosthetic heart valve implantation provide important complementary information to echocardiography for follow-up purposes. Eur Radiol. 2016 Apr;26(4):997–1006.
  • Fagman E, van Essen M, Freden Lindqvist J, et al. 18F-FDG PET/CT in the diagnosis of prosthetic valve endocarditis. Int J Cardiovasc Imaging. 2016 Apr;32(4):679–686.
  • Pizzi MN, Roque A, Fernandez-Hidalgo N, et al. Improving the diagnosis of infective endocarditis in prosthetic valves and intracardiac devices with 18F-fluorodeoxyglucose positron emission tomography/computed tomography angiography: initial results at an infective endocarditis referral center. Circulation. 2015 Sep 22;132(12):1113–1126.
  • Ricciardi A, Sordillo P, Ceccarelli L, et al. 18-Fluoro-2-deoxyglucose positron emission tomography-computed tomography: an additional tool in the diagnosis of prosthetic valve endocarditis. Int J Infect Dis. 2014 Nov;28:219–224.
  • Rouzet F, Chequer R, Benali K, et al. Respective performance of 18F-FDG PET and radiolabeled leukocyte scintigraphy for the diagnosis of prosthetic valve endocarditis. J Nucl Med. 2014 Dec;55(12):1980–1985.
  • Saby L, Laas O, Habib G, et al. Positron emission tomography/computed tomography for diagnosis of prosthetic valve endocarditis: increased valvular 18F-fluorodeoxyglucose uptake as a novel major criterion. J Am Coll Cardiol. 2013 Jun 11;61(23):2374–2382.
  • Bartoletti M, Tumietto F, Fasulo G, et al. Combined computed tomography and fluorodeoxyglucose positron emission tomography in the diagnosis of prosthetic valve endocarditis: a case series. BMC Res Notes. 2014 Jan 13;7:32.
  • Mahmood M, Kendi AT, Ajmal S, et al. Meta-analysis of 18F-FDG PET/CT in the diagnosis of infective endocarditis. J Nucl Cardiol. 2019 Jun;26(3):922–935.
  • Scholtens AM, Budde RPJ, Lam M, et al. FDG PET/CT in prosthetic heart valve endocarditis: there is no need to wait. J Nucl Cardiol. 2017 Oct;24(5):1540–1541.
  • Roque A, Pizzi MN, Fernandez-Hidalgo N, et al. Morpho-metabolic post-surgical patterns of non-infected prosthetic heart valves by [18F]FDG PET/CTA: “normality” is a possible diagnosis. Eur Heart J Cardiovasc Imaging. 2020 Jan 1;21(1):24–33.
  • Wahadat AR, Tanis W, Scholtens AM, et al. Normal imaging findings after aortic valve implantation on (18)F-fluorodeoxyglucose positron emission tomography with computed tomography. J Nucl Cardiol. 2020 Jan 23. DOI:10.1007/s12350-019-02025-y.
  • Juneau D, Pelletier-Galarneau M. Revisiting the relevance of the 3-month safety period in the evaluation of prosthetic valve endocarditis with FDG-PET/CT. J Nucl Cardiol. 2020 Feb 13. DOI:10.1007/s12350-020-02070-y.
  • Hyafil F, Rouzet F, Lepage L, et al. Role of radiolabelled leucocyte scintigraphy in patients with a suspicion of prosthetic valve endocarditis and inconclusive echocardiography. Eur Heart J Cardiovasc Imaging. 2013 Jun;14(6):586–594.
  • Blomstrom-Lundqvist C, Traykov V, Erba PA, et al. European Heart Rhythm Association (EHRA) international consensus document on how to prevent, diagnose, and treat cardiac implantable electronic device infections-endorsed by the Heart Rhythm Society (HRS), the Asia Pacific Heart Rhythm Society (APHRS), the Latin American Heart Rhythm Society (LAHRS), International Society for Cardiovascular Infectious Diseases (ISCVID) and the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS). Eur J Cardio-thorac Surg. 2020 Jan 1;57(1):e1–e31.
  • Baddour LM, Epstein AE, Erickson CC, et al. Update on cardiovascular implantable electronic device infections and their management: a scientific statement from the American Heart Association. Circulation. 2010 Jan 26;121(3):458–477.
  • Vilacosta I, Sarria C, San Roman JA, et al. Usefulness of transesophageal echocardiography for diagnosis of infected transvenous permanent pacemakers. Circulation. 1994 Jun;89(6):2684–2687.
  • Downey BC, Juselius WE, Pandian NG, et al. Incidence and significance of pacemaker and implantable cardioverter-defibrillator lead masses discovered during transesophageal echocardiography. Pacing Clin Electrophysiol. 2011 Jun;34(6):679–683.
  • Victor F, De Place C, Camus C, et al. Pacemaker lead infection: echocardiographic features, management, and outcome. Heart. 1999 Jan;81(1):82–87.
  • Klug D, Lacroix D, Savoye C, et al. Systemic infection related to endocarditis on pacemaker leads: clinical presentation and management. Circulation. 1997 Apr 15;95(8):2098–2107.
  • Dababneh AS, Sohail MR. Cardiovascular implantable electronic device infection: a stepwise approach to diagnosis and management. Cleve Clin J Med. 2011 Aug;78(8):529–537.
  • Chen W, Kim J, Molchanova-Cook OP, et al. The potential of FDG PET/CT for early diagnosis of cardiac device and prosthetic valve infection before morphologic damages ensue. Curr Cardiol Rep. 2014 Mar;16(3):459.
  • Amraoui S, Tlili G, Sohal M, et al. Early prosthetic aortic valve infection identified with the use of positron emission tomography in a patient with lead endocarditis. J Nucl Cardiol. 2016 Dec;23(6):1504–1507.
  • Cautela J, Alessandrini S, Cammilleri S, et al. Diagnostic yield of FDG positron-emission tomography/computed tomography in patients with CEID infection: a pilot study. Europace. 2013 Feb;15(2):252–257.
  • Amraoui S, Tlili G, Sohal M, et al. Contribution of PET imaging to the diagnosis of septic embolism in patients with pacing lead endocarditis. JACC Cardiovasc Imaging. 2016 Mar;9(3):283–290.
  • Tlili G, Amraoui S, Mesguich C, et al. High performances of (18)F-fluorodeoxyglucose PET-CT in cardiac implantable device infections: a study of 40 patients. J Nucl Cardiol. 2015 Aug;22(4):787–798.
  • Wong D, Rubinshtein R, Keynan Y. Alternative cardiac imaging modalities to echocardiography for the diagnosis of infective endocarditis. Am J Cardiol. 2016 Nov 1;118(9):1410–1418.
  • Ozcan C, Asmar A, Gill S, et al. The value of FDG-PET/CT in the diagnostic work-up of extra cardiac infectious manifestations in infectious endocarditis. Int J Cardiovasc Imaging. 2013 Oct;29(7):1629–1637.
  • Mahmood M, Kendi AT, Farid S, et al. Role of (18)F-FDG PET/CT in the diagnosis of cardiovascular implantable electronic device infections: a meta-analysis. J Nucl Cardiol. 2019 Jun;26(3):958–970.
  • Malecka BA, Zabek A, Debski M, et al. The usefulness of SPECT-CT with radioisotope-labeled leukocytes in diagnosing lead-dependent infective endocarditis. Adv Clin Exp Med. 2019 Jan;28(1):113–119.
  • Erba PA, Lancellotti P, Vilacosta I, et al. Recommendations on nuclear and multimodality imaging in IE and CIED infections. Eur J Nucl Med Mol Imaging. 2018 Sep;45(10):1795–1815.
  • DeSimone DC, Sohail MR. Approach to diagnosis of cardiovascular implantable-electronic-device infection. J Clin Microbiol. 2018 Jul;56(7). DOI:10.1128/JCM.01683-17.
  • Garrigos ZE, Sohail MR. Attachment is the source of all suffering: delineating mechanisms of adhesion in Staphylococcus aureus endocarditis. Eur Heart J. 2019 Oct 14;40(39):3260–3262.
  • Xiong YQ, Willard J, Kadurugamuwa JL, et al. Real-time in vivo bioluminescent imaging for evaluating the efficacy of antibiotics in a rat Staphylococcus aureus endocarditis model. Antimicrob Agents Chemother. 2005 Jan;49(1):380–387.

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