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Nucleosides, Nucleotides & Nucleic Acids Volume 30, 2011 - Issue 12
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Original Articles

Stable Isotope Dilution Mass Spectrometric Assay for PRPP Using Enzymatic Procedures

Y. Shinohara Department of Pathophysiology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan
,
Y. Suzuki Department of Pathophysiology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan
,
H. Hasegawa Department of Pathophysiology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan
,
M. Nakamura Department of Pathophysiology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan
,
T. Nishiyama Department of Drug Metabolism and Molecular Toxicology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan
,
A. Hiratsuka Department of Drug Metabolism and Molecular Toxicology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan
&
K. Ichida Department of Pathophysiology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan
 show all
Pages 1140-1146 | Received 26 Apr 2011, Accepted 24 May 2011, Published online: 01 Dec 2011

REFERENCES

  • Becker , M. A. 1976 . Patterns of phosphoribosylpyrophosphate and ribose-5-phosphate concentration and generation in fibroblasts from patients with gout and purine overproduction . J. Clin. Invest. , 57 : 308 – 318 .
  • Becker , M. A. 2001 . “ Hyperuricemia and gout ” . In The Metabolic & Molecular Bases of Inherited Disease , 8th ed. , Edited by: Scriver , C. R. , Beaudet , A. L. , Sly , W. S. and Valle , D. 2513 – 2535 . New York : McGraw-Hill .
  • Fox , I. H. and Kelley , W. N. 1971 . Phosphoribosylpyrophosphate in men: biochemical and clinical significance . Ann. Int. Med. , 74 : 424 – 433 .
  • Becker , M. A. , Meyer , L. J. , Wood , A. W. and Seegmiller , J. E. 1973 . Purine overproduction in man associated with increased phosphoribosylpyrophosphate synthetase activity . Science , 179 : 1123 – 1126 .
  • Becker , M. A. , Meyer , L. J. and Seegmiller , J. E. 1973 . Gout with purine overproduction due to increased phosphoribosylpyrophosphate synthetase activity . Am. J. Med. , 55 : 232 – 242 .
  • Tax , W. J.M. and Veerkamp , J. H. 1977 . A simple and sensitive method for estimating the concentration and synthesis of 5-phosphoribosyl 1-pyrophosphate in red blood cells . Clin. Chim. Acta , 78 : 209 – 216 .
  • Ipata , P. L. , Mura , U. , Camici , M. and Giovannitti , M. P. 1987 . A coupled optical assay for adenine phosphoribosyltransferase and its extension for the spectrometric and radioenzymatic determination of 5-phosphoribosyl-1-pyrophosphate in mixtures and in tissue extracts . Anal. Biochem. , 164 : 411 – 417 .
  • King , M. T. , Passonneau , J. V. and Veech , R. L. 1990 . Radiometric measurement of phosphoribosylpyrophosphate and ribose 5-phosphate by enzymatic procedures . Anal. Biochem. , 187 : 179 – 186 .
  • Mantsala , P. and Zalkin , H. 1984 . Glutamine nucleotide sequence of Saccharomyces cerevisiae ADE4 encoding phosphoribosylpyrophosphate amidotransferase . J. Biol. Chem. , 259 : 8478 – 8484 .
  • Hasegawa , H. , Shinohara , Y. , Hashimoto , T. , Matsuda , R. and Hayashi , Y. 2006 . Prediction of measurement uncertainty isotope dilution gas chromatography/mass spectrometry . J. Chromatogr. A , 1136 : 226 – 230 .
  • Darmaun , D. , Manary , M. J. and Matthews , D. E. 1985 . A method for measuring both glutamine and glutamate levels and stable isotopic enrichments . Anal. Biochem. , 147 : 92 – 102 .
  • Kapetanovic , I. M. , Yonekawa , W. D. and Kupferberg , H. J. 1987 . Determination of 4-aminobutyric acid, aspartate, glutamate and glutamine and their 13C stable-isotopic enrichment in brain tissue by gas chromatography-mass spectrometry . J. Chromatogr. , 414 : 265 – 274 .
  • Anderson , L. W. , Zaharevitz , D. W. and Strong , J. M. 1987 . Glutamine and glutamate: automated quantification and isotopic enrichments by gas chromatography/mass spectrometry . Anal. Biochem. , 163 : 358 – 368 .
  • Montigon , F. , Boza , J. J. and Fay , L. B. 2001 . Determination of 13C- and 15N-enrichment of glutamine by gas chromatography/mass spectrometry and gas chromatography/combustion/isotope ratio mass spectrometry after N(O,S)-ethoxycarbonyl ethyl ester derivatisation . Rapid Commun. Mass Spectrom. , 15 : 116 – 123 .
  • Shinohara , Y. , Hasegawa , H. , Kaneko , T. , Tamura , Y. , Hashimoto , T. and Ichida , K. 2010 . Analysis of [2H7]methionine, [2H4]methionine, methionine, [2H4]homocysteine and homocysteine in plasma gas chromatography-mass spectrometry to follow the fate of administered [2H7]methionine . J. Chromatogr. B , 878 : 417 – 422 .
  • Hagenfeldt , L. and Arvidsson , A. 1980 . The distribution of amino acids between plasma and erythrocytes . Clin. Chim. Acta , 100 : 133 – 141 .

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