Advanced search
Publication Cover
Nucleosides, Nucleotides & Nucleic Acids Volume 37, 2018 - Issue 12: PROCEEDINGS OF THE 17TH INTERNATIONAL SYMPOSIUM ON PURINE AND PYRIMIDINE METABOLISM IN MAN
Submit an article Journal homepage
198
Views
4
CrossRef citations to date
0
Altmetric
Conference Proceedings

The metabolism of ecto-5’-nucleotidase (CD73) inhibitor-α,β-methylene adenosine diphosphate in BALB/c mice

Marta TomczykDepartment of Biochemistry, Medical University of Gdansk, Gdansk, PolandCorrespondence[email protected]
,
Paulina MierzejewskaDepartment of Biochemistry, Medical University of Gdansk, Gdansk, Poland
,
Ewa M. SlominskaDepartment of Biochemistry, Medical University of Gdansk, Gdansk, Poland
&
Ryszard T. SmolenskiDepartment of Biochemistry, Medical University of Gdansk, Gdansk, Poland
Pages 709-716 | Received 21 Mar 2018, Accepted 05 Jun 2018, Published online: 09 Jan 2019

References

  • Colgan, S. P.; Eltzschig, H. K.; Eckle, T.; Thompson, L. F. Physiological Roles for ecto-5′-nucleotidase (CD73). Purinergic Signal. 2006, 2, 351–360.
  • Zukowska, P.; Kutryb-Zajac, B.; Toczek, M.; Smolenski, R. T.; Slominska, E. The Role of Ecto-5′-Nucleotidase in Endothelial Dysfunction and Vascular Pathologies. Pharmacol. Rep. 2015, 67, 675–681.
  • Stagg, J.; Smyth, M. J. Extracellular Adenosine Triphosphate and Adenosine in Cancer. Oncogene 2010, 29, 5346–5358.
  • Rockenbach, L.; Braganhol, E.; Dietrich, F.; Figueiró, F.; Pugliese, M.; Edelweiss, M. I. A.; Morrone, F. B.; Sévigny, J.; Battastini, A. M. O. NTPDase3 and Ecto-5′-Nucleotidase/CD73 Are Differentially Expressed during Mouse Bladder Cancer Progression. Purinergic Signal 2014, 10, 421–430.
  • Bavaresco, L.; Bernardi, A.; Braganhol, E.; Cappellari, A. R.; Rockenbach, L.; Farias, P. F.; Wink, M. R.; Delgado-Cañedo, A.; Battastini, A. M. O. The Role of Ecto-5′-Nucleotidase/CD73 in Glioma Cell Line Proliferation. Mol. Cell. Biochem. 2008, 319, 61–68.
  • Spychala, J. Tumor-Promoting Functions of Adenosine. Pharmacol. Ther. 2000, 87, 161–173.
  • Wang, L.; Zhou, X.; Zhou, T.; Ma, D.; Chen, S.; Zhi, X.; Yin, L.; Shao, Z.; Ou, Z.; Zhou, P.; et al. Ecto-5′-Nucleotidase Promotes Invasion, Migration and Adhesion of Human Breast Cancer Cells. J. Cancer Res. Clin. Oncol. 2008, 134, 365–372.
  • Rockenbach, L.; Bavaresco, L.; Fernandes Farias, P.; Cappellari, A. R.; Barrios, C. H.; Bueno Morrone, F.; Oliveira Battastini, A. M. Alterations in the Extracellular Catabolism of Nucleotides Are Involved in the Antiproliferative Effect of Quercetin in Human Bladder Cancer T24 Cells. Urol. Oncol. 2013, 31, 1204–1211.
  • Figueiró, F.; Mendes, F. B.; Corbelini, P. F.; Janarelli, F.; Jandrey, E. H.; Russowsky, D.; et al. A Monastrol-Derived Compound, LaSOM 63, Inhibits Ecto-5'nucleotidase/CD73 Activity and Induces Apoptotic Cell Death of Glioma Cell Lines. Anticancer Res. 2014, 34, 1837–1842.
  • Knapp, K.; Zebisch, M.; Pippel, J.; El-Tayeb, A.; Müller, C. E.; Sträter, N. Crystal Structure of the Human Ecto-5′-Nucleotidase (CD73): Insights into the Regulation of Purinergic Signaling. Structure 2012, 20, 2161–2173.
  • Landgraf, M.; McGovern, J. A.; Friedl, P.; Hutmacher, D. W. Rational Design of Mouse Models for Cancer Research. Trends Biotechnol. 2018, 36, 242–251.
  • Dine, J.; Deng, C. X. Mouse Models of BRCA1 and Their Application to Breast Cancer Research. Cancer Metastasis Rev. 2013, 32, 25–37.
  • Zukowska, P.; Kutryb-Zajac, B.; Jasztal, A.; Toczek, M.; Zabielska, M.; Borkowski, T.; Khalpey, Z.; Smolenski, R. T.; Slominska, E. M. Deletion of CD73 in Mice Leads to Aortic Valve Dysfunction. Biochim. Biophys. Acta. 2017, 1863, 1464–1472.
  • Smolenski, R. T.; Lachno, D. R.; Ledingham, S. J.; Yacoub, M. H. Determination of Sixteen Nucleotides, Nucleosides and Bases Using High-Performance Liquid Chromatography and Its Application to the Study of Purine Metabolism in Hearts for Transplantation. J. Chromatogr. 1990, 527, 414–420.
  • Geoghegan, J. C.; Diedrich, G.; Lu, X.; Rosenthal, K.; Sachsenmeier, K. F.; Wu, H.; Dall'Acqua, W. F.; Damschroder, M. M. Inhibition of CD73 AMP Hydrolysis by a Therapeutic Antibody with a Dual, Non-Competitive Mechanism of Action. MABS 2016, 8, 454–467.
  • Koszałka, P.; Pryszlak, A.; Gołuńska, M.; Kolasa, J.; Stasiłojć, G.; Składanowski, A.; Bigda, J. Inhibition of CD73 Stimulates the Migration and Invasion of B16F10 Melanoma Cells in Vitro, but Results in Impaired Angiogenesis and Reduced Melanoma Growth in Vivo. Oncol. Rep. 2014, 31, 819–827.
  • Wang, L.; Fan, J.; Thompson, L. F.; Zhang, Y.; Shin, T.; Curiel, T. J.; Zhang, B. CD73 Has Distinct Roles in Nonhematopoietic and Hematopoietic Cells to Promote Tumor Growth in Mice. J. Clin. Invest. 2011, 121, 2371–2382.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.