HMGA2 rs968697 T > C polymorphism is associated with the risk of colorectal cancer

Reference

• Bray, F.; Ferlay, J.; Soerjomataram, I.; Siegel, R. L.; Torre, L. A.; Jemal, A. Global Cancer Statistics 2018: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J. Clin. 2018, 68, 394–424. DOI: 10.3322/caac.21492.
   PubMed Web of Science ®Google Scholar
• Sun, J.; Sun, B.; Sun, R.; Zhu, D.; Zhao, X.; Zhang, Y.; Dong, X.; Che, N.; Li, J.; Liu, F.; et al. HMGA2 Promotes Vasculogenic Mimicry and Tumor Aggressiveness by Upregulating Twist1 in Gastric Carcinoma. Sci. Rep. 2017, 7, 2229. DOI: 10.1038/s41598-017-02494-6.
   PubMed Web of Science ®Google Scholar
• Zhang, H.; Tang, Z.; Deng, C.; He, Y.; Wu, F.; Liu, O.; Hu, C. HMGA2 is Associated with the Aggressiveness of Tongue Squamous Cell Carcinoma. Oral Dis. 2017, 23, 255–264. DOI: 10.1111/odi.12608.
   PubMed Web of Science ®Google Scholar
• Wu, J.; Zhang, S.; Shan, J.; Hu, Z.; Liu, X.; Chen, L.; Ren, X.; Yao, L.; Sheng, H.; Li, L.; et al. Elevated HMGA2 Expression is Associated with Cancer Aggressiveness and Predicts Poor Outcome in Breast Cancer. Cancer Lett. 2016, 376, 284–292. DOI: 10.1016/j.canlet.2016.04.005.
   PubMed Web of Science ®Google Scholar
• Wang, X.; Liu, X.; Li, A. Y.; Chen, L.; Lai, L.; Lin, H. H.; Hu, S.; Yao, L.; Peng, J.; Loera, S.; et al. Overexpression of HMGA2 Promotes Metastasis and Impacts Survival of Colorectal Cancers. Clin. Cancer Res. 2011, 17, 2570–2580. DOI: 10.1158/1078-0432.CCR-10-2542.
   PubMed Web of Science ®Google Scholar
• Wu, J.; Wang, Y.; Xu, X.; Cao, H.; Sahengbieke, S.; Sheng, H.; Huang, Q.; Lai, M. Transcriptional Activation of FN1 and IL11 by HMGA2 Promotes the Malignant Behavior of Colorectal Cancer. Carcinogenesis 2016, 37, 511–521. DOI: 10.1093/carcin/bgw029.
   PubMed Web of Science ®Google Scholar
• Wang, Y.; Hu, L.; Wang, J.; Li, X.; Sahengbieke, S.; Wu, J.; Lai, M. HMGA2 Promotes Intestinal Tumorigenesis by Facilitating MDM2-Mediated Ubiquitination and Degradation of p53. J. Pathol. 2018, 246, 508–518. DOI: 10.1002/path.5164.
   PubMed Web of Science ®Google Scholar
• Mansoori, B.; Mohammadi, A.; Naghizadeh, S.; Gjerstorff, M.; Shanehbandi, D.; Shirjang, S.; Najafi, S.; Holmskov, U.; Khaze, V.; Duijf, P. H. G.; Baradaran, B. Baradaran, B. miR-330 Suppresses EMT and Induces Apoptosis by Downregulating HMGA2 in Human Colorectal Cancer. J. Cell. Physiol. 2020, 235, 920–931. DOI: 10.1002/jcp.29007.
   PubMed Web of Science ®Google Scholar
• Helmke, B. M.; Markowski, D. N.; Meyer, A.; Bullerdiek, J. The Expression of HMGA2 Varies Strongly among Colon Carcinomas. Anticancer Res. 2012, 32, 1589–1593.
   PubMed Web of Science ®Google Scholar
• Li, L.; Zhuo, Z.; Yang, Z.; Zhu, J.; He, X.; Yang, Z.; Zhang, J.; Xin, Y.; He, J.; Zhang, T. HMGA2 Polymorphisms and Hepatoblastoma Susceptibility: A Five-Center Case-Control Study. Pharmgenomics Pers. Med. 2020, 13, 51–57.
   PubMed Web of Science ®Google Scholar
• Boyle, A. P.; Hong, E. L.; Hariharan, M.; Cheng, Y.; Schaub, M. A.; Kasowski, M.; Karczewski, K. J.; Park, J.; Hitz, B. C.; Weng, S.; et al. Annotation of Functional Variation in Personal Genomes Using RegulomeDB. Genome Res. 2012, 22, 1790–1797.
   PubMed Web of Science ®Google Scholar
• Xu, Z.; Taylor, J. A. SNPinfo: Integrating GWAS and Candidate Gene Information into Functional SNP Selection for Genetic Association Studies. Nucleic Acids Res. 2009, 37, W600–W605. DOI: 10.1093/nar/gkp290.
   PubMed Web of Science ®Google Scholar
• Ni, W.; Wang, X.; Sun, Y.; Gao, X. Meta-Analysis of the Association between MALAT1 rs619586 a > G Polymorphism and Cancer Risk. J. Int. Med. Res. 2020, 48, 300060520941969. DOI: 10.1177/0300060520941969.
   PubMed Web of Science ®Google Scholar
• Gao, X.; Zhu, Z.; Zhang, S. miR-146a rs2910164 Polymorphism and the Risk of Colorectal Cancer in Chinese Population. J. Cancer Res. Ther. 2018, 14, S97–S99. DOI: 10.4103/0973-1482.165864.
   PubMed Web of Science ®Google Scholar
• Xiao, Y.; Dong, Z.; Zhu, J.; You, J.; Fan, J. Association between ACE A240T Polymorphism and Cancer Risk: A Meta-Analysis. J. Int. Med. Res. 2019, 47, 5917–5925. DOI: 10.1177/0300060519882559.
   PubMed Web of Science ®Google Scholar
• Cheng, J.; Zhuo, Z.; Yang, L.; Zhao, P.; Zhang, J.; Zhou, H.; He, J.; Li, P. HMGA2 Gene Polymorphisms and Wilms Tumor Susceptibility in Chinese Children: A Four-Center Case-Control Study. Biotechnol. Appl. Biochem. 2020, 67, 939–945. DOI: 10.1002/bab.1857.
   PubMedGoogle Scholar
• Liu, J.; Hua, R. X.; Cheng, Y.; Zhu, J.; Zhang, J.; Cheng, J.; Zhou, H.; Xia, H.; Bian, J.; He, J. HMGA2 Gene rs8756 a > C Polymorphism Reduces Neuroblastoma Risk in Chinese Children: A Four-Center Case-Control Study. OncoTargets Ther. 2020, 13, 465–472. DOI: 10.2147/OTT.S229975.
   PubMed Web of Science ®Google Scholar
• Zhou, J.; Wang, P.; Zhang, R.; Huang, X.; Dai, H.; Yuan, L.; Ruan, J. Association of HMGA2 Polymorphisms with Glioma Susceptibility in Chinese Children. Pharmgenomics. Pers. Med. 2021, 14, 601–607. DOI: 10.2147/PGPM.S310780.
   PubMed Web of Science ®Google Scholar
• McLaughlin, R. P.; He, J.; van der Noord, V. E.; Redel, J.; Foekens, J. A.; Martens, J. W. M.; Smid, M.; Zhang, Y.; van de Water, B. A Kinase Inhibitor Screen Identifies a Dual cdc7/CDK9 Inhibitor to Sensitise Triple-Negative Breast Cancer to EGFR-Targeted Therapy. Breast Cancer Res. 2019, 21, 77. DOI: 10.1186/s13058-019-1161-9.
   PubMed Web of Science ®Google Scholar
• Mao, C. G.; Jiang, S. S.; Shen, C.; Long, T.; Jin, H.; Tan, Q. Y.; Deng, B. BCAR1 Promotes Proliferation and Cell Growth in Lung Adenocarcinoma via Upregulation of POLR2A. Thorac. Cancer. 2020, 11, 3326–3336. DOI: 10.1111/1759-7714.13676.
   PubMed Web of Science ®Google Scholar