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Nucleosides, Nucleotides & Nucleic Acids Volume 26, 2007 - Issue 6-7
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Original Articles

Asymmetric Synthesis of Novel Apio Carbocyclic Nucleoside Analogues as Potential Antiviral and Antitumor Agent

Lak Shin Jeong College of Pharmacy, Ewha Womans University, Seoul, Korea
,
Jeong A. Lee College of Pharmacy, Ewha Womans University, Seoul, Korea
,
Hyung Ryong Moon College of Pharmacy and Research Institute for Drug Development, Pusan National University, Busan, Korea
,
Hea Ok Kim College of Pharmacy, Ewha Womans University, Seoul, Korea
,
Kang Man Lee College of Pharmacy, Ewha Womans University, Seoul, Korea
,
Hyun Joo Lee College of Pharmacy, Ewha Womans University, Seoul, Korea
&
Moon Woo Chun College of Pharmacy, Seoul National University, Seoul, Korea
 show all
Pages 721-724 | Published online: 10 Dec 2007

REFERENCES

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  • Wolfe , M. S. and Borchardt , R. T. 1991 . S-adenosyl-L-homocysteine hydrolase as a target for antiviral chemotherapy . J. Med. Chem. , 34 : 1521 – 1530 .
  • Jeong , L. S. , Yoo , S. J. , Lee , K. M. , Koo , M. J. , Choi , W. J. , Kim , H. O. , Moon , H. R. , Lee , M. Y. , Park , J. G. , Lee , S. K. and Chun , M. W. 2003 . Design, synthesis, and biological evaluation of fluoroneplanocin a as the novel mechanism-based inhibitor of S-adenosylhomocysteine hydrolase . J. Med. Chem. , 46 : 201 – 203 .
  • Nair , V. and Jahnke , T. S. 1995 . Antiviral activities of isomeric dideoxynucleosides of D- and L-related stereochemistry . Antimicrob. Agents Chemother. , 39 : 1017 – 1029 .
  • Sells , T. B. and Nair , V. 1994 . Synthetic approaches to novel cis and trans dideoxynucleosides of the apiose family . Tetrahedron , 50 : 117 – 138 .
  • Jeong , L. S. , Kim , H. O. , Moon , H. R. , Hong , J. H. , Yoo , S. J. , Choi , W. J. , Chun , M. W. and Lee , C.-K. 2001 . Synthesis and structure-activity relationships of novel apio and thioapio dideoxydidehydronucleosides as anti-HCMV agents . J. Med. Chem. , 44 : 806 – 813 .
  • Moon , H. R. , Kim , H. O. , Lee , K. M. , Chun , M. W. , Kim , J. H. and Jeong , L. S. 2002 . Stereoselective synthesis of a novel apio analogue of neplanocin a as potential S-adenosylhomocysteine hydrolase inhibitor . Organic Lett. , 4 : 3501 – 3503 .
  • Grubbs , R. H. and Chang , S. 1998 . Recent advances in olefin metathesis and its application in organic synthesis . Tetrahedron , 54 : 4413 – 4450 .
  • Grubbs , R. H. 2004 . Olefin metathesis . Tetrahedron , 60 : 7117 – 7140 .

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