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Original Articles

Synthesis of 1′-C-Fluoromethyladenosine

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Pages 1431-1434 | Published online: 05 Dec 2007

REFERENCES

  • Sommadossi , J.-P. and LaColla , P. 2001 . Preparation of antiviral nucleosides and methods for treating hepatitis C virus WO 2001090121, CAN 136:6296, 296pp
  • Sommadossi , J.-P. and LaColla , P. 2001 . Methods and compositions using modified nucleosides for treating flaviviruses and pestiviruses WO 2001, 092282, CAN 136:590, 302pp
  • Afdhal , N. , Rodriguez-Torres , M. , Lawitz , E. , Godofsky , E. , Chao , G. , Fielman , B. , Knox , S. and Brown , N. 2005 . Enhanced antiviral efficacy for valopicitabine (NM283) plus PEG-Interferon in hepatitis C patients with HCV genotype-1 infection: Results of a phase Iia multicenter trial . J. Hepatol. , 42 : 39 – 40 . (Suppl. 2)
  • Zhou , X. J. , Afdhal , N. , Godofsky , E. , Dienstag , J. , Rustgi , V. , Schick , L. , McInery , D. , Fielman , B. and Brown , N. 2005 . Pharmacokinetics and pharmacodynamics of valopicitabine (NM 283), a new nucleoside HCV polymerase inhibitor: Results of a phase I/II dose-escalation trial in patients with HCV-1 infection . J. Hepatol. , 42 : 229 (Suppl. 2)
  • Molas , P. , Díaz , Y. , Matheu , M. I. and Castillón , S. 2003 . Synthesis of 1′-C-fluoromethyl-ddC by Selectfluor-induced glycosylation of exo-glycals . Synlett , 2 : 207 – 210 .
  • Lakhrissi , M. and Chapleur , Y. 1994 . Dichloromethylenation of lactones. 6. Efficient synthesis of dichloroolefins from lactones and acetates using triphenylphosphine and tetrachloromethan . J. Org.Chem. , 59 ( 19 ) : 5752 – 5757 .
  • Chapleur , Y. 1984 . A convenient synthesis of substituted chiral tetrahydrofurans from sugar. γ -lactones . J. Chem. Soc., Chem. Commun. , : 449 – 450 .
  • Lakhrissi , M. , Bandzouzi , A. and Chapleur , Y. 1995 . Carbohydrate Lett. , 1 : 307 – 314 .
  • Buckwold , V. E. , Beer , B. E. and Donis , R. O. 2003 . Bovine viral diarrhea virus as a surrogate model of hepatitis C virus for the evaluation of antiviral agents . Antiviral Res. , 60 : 1 – 15 .

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