RNA Cleavage by 2,9-Diamino-1,10-Phenanthroline PNA Conjugates

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• PNA1 PNA2 were purified on a Phenomenex Jupiter Proteo (4 μ m 250 × 4.6 mm) column at 60°C using a flow rate of 1ml/min and a linear gradient of 10% B for 20 min, then 10–37% B for 20 min was used. Retention times were 35 min for PNA1 and 32 min for PNA2 PNA3 PNA4 were purified on a Phenomenex Jupiter Proteo (4 μ m 250 × 10 mm) column at 60°C using a flow rate of 4 ml/min and a linear gradient of 10% B for 20 min, then 10–37% B for 20 min was used. Retention times were 32 min for PNA3 and 27 min for PNA4
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