113
Views
19
CrossRef citations to date
0
Altmetric
Original Articles

2′,4′-BNANC: A Novel Bridged Nucleic Acid Analogue with Excellent Hybridizing and Nuclease Resistance Profiles

, , , , &
Pages 1625-1628 | Published online: 05 Dec 2007

REFERENCES

  • Stein , C. A. and King , A. M. 1998 . Applied Antisense Oligonucleotide Technology , New York : Willy-Liss .
  • Buchini , S. and Leumann , C. J. 2003 . Recent improvement in antigene technology . Curr. Opin. Chem. Biol. , 7 : 117 – 130 .
  • Imanishi , T. and Obika , S. 2002 . BNAs: Novel nucleic acid analogues with a bridged sugar moiety . Chem. Commun. , : 1653 – 1659 .
  • Obika , S. , Nandu , D. , Hari , Y. , Morio , K. , In , Y. , Ishida , T. and Imanishi , T. 1997 . Synthesis of 2′-O-4′-C-methyleneuridine and -cytidine novel bicyclic nucleosides having a fixed C3′-endo sugar puckering . Tetrahedron Lett. , 38 : 8735 – 8738 .
  • Sing , S. K. , Nielsen , P. , Koshkin , A. A. and Wengel , J. 1998 . LNA (locked nucleic acids): Synthesis and high affinity nucleic acid recognition . Chem. Commun. , : 455 – 456 .
  • Petersen , M. and Wengel , J. 2003 . LNA: A versatile tool for therapeutics and genomics . Trends. Biotechnol. , 21 : 74 – 81 .
  • Jespen , J. S. and Wengel , J. 2004 . Locked nucleic acid: A potent nucleic acid analogue in therapeutics and biotechnology . Curr. Opin. Drug Discovery Dev. , 7 : 188 – 194 .
  • Hari , Y. , Obika , S. , Ohnishi , K. , Eguchi , K. , Osaki , T. , Ohishi , H. and Imanishi , T. 2006 . Synthesis and properties of 2′-O,4′-C methyleneoxomethylene bridged nucleic acids . Biorg. Med. Chem. , 14 : 1029 – 1038 .
  • Rahman , S. M.A. , Seki , S. , Utsuki , K. , Obika , S. , Miyashita , K. and Imanishi , T. 2005 . Synthesis and properties of 2′,4′-BNANC, a second-generation BNA . Nucleic Acids Symp. Ser. , 49 : 5 – 6 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.