Immunocytochemical Detection of hENT1 and hCNT1 in Normal Tissues, Lung Cancer Cell Lines, and NSCLC Patient Samples

REFERENCES

• Peters , G. J. , van der Wilt , C. L. , Van Moorsel , C. J. , Kroep , J. R. , Bergman , A. M. and Ackland , S. P. 2000 . Basis for effective combination cancer chemotherapy with antimetabolites . Pharmacol. Ther. , 87 : 227 – 253 .
   PubMed Web of Science ®Google Scholar
• Pastor-Anglada , M. , Cano-Soldado , P. , Molina-Arcas , M. , Lostao , M. P. , Larráyoz , I. , Martínez-Picado , J. and Casado , F. J. 2005 . Cell entry and export of nucleoside analogues . Virus Res. , 107 : 151 – 164 .
   PubMed Web of Science ®Google Scholar
• Clarke , M. L. , Mackey , J. R. , Baldwin , S. A. , Young , J. D. and Cass , C. E. 2002 . The role of membrane transporters in cellular resistance to anticancer nucleoside drugs . Cancer Treat. Res. , 112 : 27 – 47 .
   PubMedGoogle Scholar
• Sundaram , M. , Yao , S. Y. , Ingram , J. C. , Berry , Z. A. , Abidi , F. , Cass , C. E. , Baldwin , S. A. and Young , J. D. 2001 . Topology of a human equilibrative, nitrobenzylthioinosine (NBMPR)-sensitive nucleoside transporter (hENT1) implicated in the cellular uptake of adenosine and anti-cancer drugs . J. Biol. Chem. , 276 : 45270 – 45275 .
   PubMed Web of Science ®Google Scholar
• Sigmond , J. , Kamphuis , J. A. , Laan , A. C. , Hoebe , E. K. , Bergman , A. M. and Peters , G. J. 2007 . The synergistic interaction of gemcitabine and cytosine arabinoside with the ribonucleotide reductase inhibitor triapine is schedule dependent . Biochem. Pharmacol. , 73 : 1548 – 1557 .
   PubMed Web of Science ®Google Scholar
• Pastor-Anglada , M. and Casado , F. J. 2006 . “ Nucleoside transport into cells: Role of nucleoside transporters SLC28 and SLC29 in cancer chemotherapy ” . In Deoxynucleoside Analogs in Cancer Therapy , Edited by: Peters , G. J. 1 – 28 . Totowa, NJ : Humana Press .
   Google Scholar
• Giovannetti , E. , Del , T. M. , Mey , V. , Funel , N. , Nannizzi , S. , Ricci , S. , Orlandini , C. , Boggi , U. , Campani , D. , Del Chiaro , M. , Iannopollo , M. , Bevilacqua , G. , Mosca , F. and Danesi , R. 2006 . Transcription analysis of human equilibrative nucleoside transporter-1 predicts survival in pancreas cancer patients treated with gemcitabine . Cancer Res. , 66 : 3928 – 3935 .
   PubMed Web of Science ®Google Scholar
• Hubeek , I. , Stam , R. W. , Peters , G. J. , Broekhuizen , R. , Meijerink , J. P. , van Wering , E. R. , Gibson , B. E. , Creutzig , U. , Zwaan , C. M. , Cloos , J. , Kuik , D. J. , Pieters , R. and Kaspers , G. J. 2005 . The human equilibrative nucleoside transporter 1 mediates in vitro cytarabine sensitivity in childhood acute myeloid leukaemia . Br. J. Cancer , 93 : 1388 – 1394 .
   PubMed Web of Science ®Google Scholar
• Galmarini , C. M. , Thomas , X. , Calvo , F. , Rousselot , P. , Rabilloud , M. , El Jaffari , A. , Cros , E. and Dumontet , C. 2002 . In vivo mechanisms of resistance to cytarabine in acute myeloid leukaemia . Br. J. Haematol. , 117 : 860 – 868 .
   PubMed Web of Science ®Google Scholar
• Galmarini , C. M. , Thomas , X. , Calvo , F. , Rousselot , P. , El Jafaari , A. , Cros , E. and Dumontet , C. 2002 . Potential mechanisms of resistance to cytarabine in AML patients . Leuk. Res. , 26 : 621 – 629 .
   PubMed Web of Science ®Google Scholar
• Mori , R. , Ishikawa , T. , Ichikawa , Y. , Taniguchi , K. , Matsuyama , R. , Ueda , M. , Fujii , Y. , Endo , I. , Togo , S. , Danenberg , P. V. and Shimada , H. 2007 . Human equilibrative nucleoside transporter 1 is associated with the chemosensitivity of gemcitabine in human pancreatic adenocarcinoma and biliary tract carcinoma cells . Oncol. Rep. , 17 : 1201 – 1205 .
   PubMed Web of Science ®Google Scholar
• Achiwa , H. , Oguri , T. , Sato , S. , Maeda , H. , Niimi , T. and Ueda , R. 2004 . Determinants of sensitivity and resistance to gemcitabine: the roles of human equilibrative nucleoside transporter 1 and deoxycytidine kinase in non-small cell lung cancer . Cancer Sci. , 95 : 753 – 757 .
   PubMed Web of Science ®Google Scholar
• Oguri , T. , Achiwa , H. , Muramatsu , H. , Ozasa , H. , Sato , S. , Shimizu , S. , Yamazaki , H. , Eimoto , T. and Ueda , R. 2007 . The absence of human equilibrative nucleoside transporter 1 expression predicts nonresponse to gemcitabine-containing chemotherapy in non-small cell lung cancer . Cancer Lett. , 256 : 112 – 119 .
   PubMed Web of Science ®Google Scholar