Substrate Specificity of Thymidine Phosphorylase of E. Coli: Role of Hydroxyl Groups

REFERENCES

• Pugmire , M.J. and Ealick , S.E. 2002 . Structural analyses reveal two distinct families of nucleoside phosphorylases . Biochem. J. , 361 : 1 – 25 .
   PubMed Web of Science ®Google Scholar
• Edwards , P.N. 2006 . A kinetic, modeling and mechanistic re-analysis of thymidine phosphorylase and some related enzymes . J. Enz. Inhib. Med. Chem. , 21 : 483 – 518 .
   PubMed Web of Science ®Google Scholar
• Walter , M.R. , Cook , W.J. , Cole , L.B. , Short , S.A. , Koszalka , G.W. , Krenitsky , T.A. and Ealick , S.E. 1990 . Three-dimensional structure of thymidine phosphorylase from Escherichia coli at 2.8 A resolution . J. Biol. Chem. , 265 : 14016 – 14022 .
   PubMed Web of Science ®Google Scholar
• Pugmire , M.J. , Cook , W.J. , Jasanoff , A. , Walter , M.R. and Ealick , S.E. 1998 . Structural and theoretical studies suggest domain movement produces an active conformation of thymidine phosphorylase . J. Mol. Biol. , 281 : 285 – 299 .
   PubMed Web of Science ®Google Scholar
• Takebayashi , Y. , Yamada , K. , Miyadera , K. , Sumizawa , T. , Furukawa , T. , Kinoshita , F. , Aoki , D. , Okumura , H. , Yamada , Y. , Akiyama , S. and Aikou , T. 1996 . The activity and expression of thymidine phosphorylase in human solid tumours . Eur. J. Cancer , 32A : 1227 – 1232 .
   PubMed Web of Science ®Google Scholar
• Utagawa , T. 1999 . Enzymatic preparation of nucleoside antibiotics . J. Mol. Catalysis B , 6 : 215 – 222 .
   Web of Science ®Google Scholar
• Barai , V.N. , Zinchenko , A.I. , Eroshevskaia , L.A. , Kalinichenko , E.N. , Kulak , T.I. and Mikhailopulo , I.A. 2002 . A Universal Biocatalyst for the Preparation of Base- and Sugar-Modified Nucleosides via an Enzymatic Transglycosylation . Helvetica Chimica Acta , 85 : 1901 – 1908 .
   Web of Science ®Google Scholar
• Panova , N.G. , Alexeev , C.S. , Kuzmichov , A.S. , Shcheveleva , E.V. , Gavryushov , S.A. , Polyakov , K.M. , Kritzyn , A.M. , Mikhailov , S.N. , Esipov , R.S. and Miroshnikov , A.I. 2007 . Substrate specificity of E. coli thymidine phosphorylase . Biochemistry (Moscow) , 72 : 21 – 28 .
   PubMed Web of Science ®Google Scholar
• Rick , S.W. , Abashkin , Y.G. , Hilderbrandt , R.L. and Burt , S.K. 1999 . Computational studies of the domain movement and the catalytic mechanism of thymidine phosphorylase . Proteins , 37 : 242 – 252 .
   PubMed Web of Science ®Google Scholar