Development of LC-MS Method for Detection of Mutant Uromodulin Protein

M. Yasuda Laboratory of Analytical Chemistry, School of Pharmaceutical Sciences, Teikyo University, Kanagawa, Japan

K. Kaneko Laboratory of Analytical Chemistry, School of Pharmaceutical Sciences, Teikyo University, Kanagawa, Japan

H. Hachisu Laboratory of Analytical Chemistry, School of Pharmaceutical Sciences, Teikyo University, Kanagawa, Japan

M. Ochiai Laboratory of Analytical Chemistry, School of Pharmaceutical Sciences, Teikyo University, Kanagawa, Japan

T. Yamanobe Central Laboratory of Analytical Biochemistry, School of Medicine, Teikyo University, Tokyo, Japan

K. Mawatari Laboratory of Analytical Chemistry, School of Pharmaceutical Sciences, Teikyo University, Kanagawa, Japan

K. Nakagomi Laboratory of Analytical Chemistry, School of Pharmaceutical Sciences, Teikyo University, Kanagawa, Japan

N. Minoura Graduate School of Bionics, Tokyo University of Technology, Tokyo, Japan

M. Hosoyamada Division of Pharmacotherapeutics, Faculty of Pharmacy, Keio University, Tokyo, Japan

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Devuyst , O. , Dahan , K. and Pirson , Y. 2005 . Tamm-Horsfall protein or uromodulin: new ideas about an old molecule . Nephrol. Dial. Transplant , 20 : 1290 – 1294 .
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Takiue , Y. , Hosoyamada , M. , Yokoo , T. , Kimura , M. , Ochiai , M. , Kaneko , K. , Ichida , K. , Hosoya , T. and Shibasaki , T. 2008 . Production and characterization of transgenic mice harboring mutant human UMOD gene . Nucleosides Nucleotides Nucleic Acids , 27 : 596 – 600 .
PubMed Web of Science ®Google Scholar
Kaneko , K. , Yamanobe , T. , Onoda , M. , Mawatari , K. , Nakagomi , K. and Fujimori , S. 2005 . Analysis of urinary calculi obtained from a patient with idiopathic hypouricemia using micro area x-ray diffractometry and LC-MS . Urol. Res. , 33 : 415 – 421 .
PubMed Web of Science ®Google Scholar

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Development of LC-MS Method for Detection of Mutant Uromodulin Protein

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Development of LC-MS Method for Detection of Mutant Uromodulin Protein

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