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III. OLIGONUCLEOTIDES: Biological Activity

Synthesis, Biophysical and Biological Evaluations of Novel Antisense Oligonucleosides Containing Dephosphono-Internucleosidic Linkages

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Pages 1087-1090 | Published online: 16 Feb 2007

References

  • Debart , F. , Vasseur , J.-J. , Sanghvi , Y. S. and Cook , P. D. Tetrahedron Lett. , 33 2645 – 2648 .
  • Sanghvi , Y. S. and Cook , P. D. 1992, 1993 . “ Towards Second Generation Synthetic Backbones for Antisense Oligonucleosides ” . In Nucleosides and Nucleotides as Antitumor and Antiviral Agents , Edited by: Chu , C. K. and Backer , D. C. p 311 – 324 . New York : Plenum Press .
  • Vasseur , J.-J. , Debart , F. , Sanghvi , Y. S. and Cook , P. D. 1992 . J. Am. Chem. Soc. , 114 : 4006 – 4007 .
  • Sanghvi , Y. S. , Ross , B. , Bharadwaj , R. and Vasseur , J-J. 1994 . Tetrahedron Lett. , 35 : 4697 – 4700 . For the synthesis of 5 see
  • Sanghvi , Y. S. , Bharadwaj , R. , Debart , F. and DeMesmaeker , A. 1994 . Synthesis , in press, For the synthesis of 6 see
  • Morvan , F. , Sanghvi , Y. S. , Perbost , M. , Fraser , A. and Cook , P. D. Abstr. Pap. Amer. Chem. Soc. Synthesis of 5′-O-amino-2′-deoxynucleosides as building blocks for nonionic antisense oligonucleotides. 206th American Chemical Society Meeting . Aug. 22–27 1993 , Chicago, IL. Vol. 1–2 , pp. 206 Carb 25, and manuscript in preparation.
  • Hoshiko , T. , Fraser , A. , Perbost , M. , Dimock , S. , Cook , P. D. and Sanghvi , Y. S. 1994 . CARB 35 (poster presentation) . 207th ACS National Meeting . March 13–17 1994 , San Diego, CA. For the synthesis of mixed dimers see:
  • Cummins , L. , Owens , S. , Sanghvi , Y. S. , Vasseur , J.-J. , Debart , F. and Morvan , F. Nucleic Acids Res. , submitted
  • Monia , B. Dean , N. Unpublished results
  • Griffey , R. 1994 . Carbohydrate Modifications in Antisense Research, ACS Symposium Series No. 580 , Edited by: Sanghvi , Y. S. and Cook , P. D. Washington, DC : ACS Publications . in press
  • Sanghvi , Y. S. and Cook , P. D. 1994 . Carbohydrate Modifications in Antisense Research, ACS Symposium Series No. 580 , Edited by: Sanghvi , Y. S. and Cook , P. D. Washington, DC : ACS Publications . in press

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