ALTERATION OF PULMONARY CYTOCHROME P-450 SYSTEM: EFFECTS OF ASPHALT FUME CONDENSATE EXPOSURE

References

• Asphalt Institute . 1990 . Report to OSHA and NIOSH: Status of Asphalt Industry Steering Committee research program on the health effects of asphalt fumes and recommendation fora worker health standard , Lexington, KY : Asphalt Institute .
   Google Scholar
• Bartsch , H. , Rojas , M. , Nair , U. , Nair , J. and Alexandrov , K. 1999 . Genetic cancer susceptibility and DNA adducts: Studies in smokers, tobacco chewers, and coke oven workers . Cancer Detect. Prevent. , 23 : 445 – 453 .
   PubMedGoogle Scholar
• Burgaz , S. , Borm , P. J. and Jongeneelen , F. J. 1992 . Evaluation of urinary excretion of 1-hydroxypyrene and thioethers in workers exposed to bitumen fumes . Int. Arch. Occup. Environ. Health , 63 : 397 – 401 .
   PubMed Web of Science ®Google Scholar
• Burgaz , S. , Erdem , O. , Karahalil , B. and Karakaya , A. E. 1998 . Cytogenetic biomonitoring of workers exposed to bitumen fumes . Mutat. Res. , 419 : 123 – 130 .
   PubMed Web of Science ®Google Scholar
• Burke , M. D. and Mayer , R. T. 1974 . Ethoxyresorufin: direct fluorimetric assay of a microsomal O-dealkylation which is preferentially inducible by 3-methylcholanthrene . Drug Metab. Dispos. , 2 : 583 – 588 .
   PubMed Web of Science ®Google Scholar
• Burr, G. A., and Miller, A. K. 1996. NIOSH Health Hazard Evaluation Report. HETA 96-0072-2603. Staker Construction Company, Casa Grande, AZ.
   Google Scholar
• Christou , M. , Wilson , N. M. and Jefcoate , C. R. 1987 . Expression and function of three cytochrome P-450 isozymes in rat extrahepatic tissues . Arch. Biochem. Biophys. , 258 : 519 – 534 .
   PubMed Web of Science ®Google Scholar
• Estabrook , R. W. , Baron , J. , Peterson , J. and lshimura , Y. 1972 . Oxygenated cytochrome P-450 as an intermediate in hydroxylation reactions . Biochem. Soc. Symp. , 34 : 159 – 185 .
   PubMedGoogle Scholar
• Fuchs , J. , Hengstler , J. G. , Boettler , G. and Oesch , F. 1996 . Primary DNA damage in peripheral mononuclear blood cells of workers exposed to bitumen-based products . Int. Arch. Occup. Environ. Health , 68 : 141 – 146 .
   PubMed Web of Science ®Google Scholar
• Gamble , J. F. , Nicolich , M. J. , Barone , N. J. and Vincent , W. J. 1999 . Exposure-response of asphalt fumes with changes in pulmonary function and symptoms . Scand. J. Work Environ. Health , 25 : 186 – 206 .
   PubMed Web of Science ®Google Scholar
• Garshick , E. , Schenker , M. B. , Munoz , A. , Segal , M. , Smith , T. J. , Woskie , S. R. , Hammond , S. K. and Speizer , F. E. 1987 . A case-control study of lung cancer and diesel exhaust exposure in railroad workers . Am. Rev. Respir. Dis. , 135 : 1242 – 1248 .
   PubMed Web of Science ®Google Scholar
• Heddle , J. A. , Cimino , M. C , Hayashi , M. , Romagna , F. , Shelby , M. D. , Tucker , J. D. , Vanparys , P. and MacGregor , J. T. 1991 . Micronuclei as an index of cytogenetic damage: Past, present, and future . Environ. Mol. Mutagen. , 18 : 277 – 291 .
   PubMed Web of Science ®Google Scholar
• Hermann , M. 1981 . Synergistic effects of individual polycyclic aromatic hydrocarbons on the mutagenicity of their mixtures . Mutat. Res. , 90 : 399 – 409 .
   PubMed Web of Science ®Google Scholar
• International Agency for Research on Cancer . 1985 . Polynuclear compounds, bitumens, coal-tars and derived products, shale oils and soots, part 4 . IARC Monogr. Eval. Carcinogen. Risk Chem. Hum. , 35
   Google Scholar
• Jarvholm , B. , Nordstrom , G. , Hogstedt , B. , Levin , J. O. , Wahlstrom , J. , Ostman , C and Bergendahl , C. 1999 . Exposure to polycyclic aromatic hydrocarbons and genotoxic effects on nonsmoking Swedish road pavement workers . Scand. J. Work Environ. Health , 25 : 131 – 136 .
   PubMed Web of Science ®Google Scholar
• Jones , K. G. , Holland , J. F. and Fouts , J. R. 1982 . Benzo(a)pyrene hydroxylase activity in enriched populations of Clara cells and alveolar type Il cells from control and beta-naphthoflavone-pretreated rats . Cancer Res. , 42 : 4658 – 4663 .
   PubMed Web of Science ®Google Scholar
• Kiyohara , C , Nakanishi , Y. , lnutsuka , S. , Takayama , K. , Hara , N. , Motohiro , A. , Tanaka , K. , Kono , S. and Hirohata , T. 1998 . The relationship between CYP1A1 aryl hydrocarbon hydroxylase activity and lung cancer in a Japanese population . Pharmacogenetics , 8 : 315 – 323 .
   PubMedGoogle Scholar
• Kriech , A. J. , Kurek , J. T. and Wisse) , H. L. 1999 . Effects of mode of generation on the composition of asphalt fumes . Polycyclic Aromatic Compounds , 14/15 : 179 – 188 .
   Web of Science ®Google Scholar
• Ma , J. Y. C , Barger , M. W. , Kreich , A. J. and Castranova , V. 2000 . Effects of asphalt fume condensate exposure on acute pulmonary responses . Arch. Toxicol. , 74 : 452 – 459 .
   PubMed Web of Science ®Google Scholar
• Ma , J. Y. C. , Frazer , D. , Barger , M. W. , Tomblyn , S. , Stone , S. , Robinson , V. A. and Castranova , V. 2001 . Effects of asphalt fume exposure on the pulmonary cytochrome P-450 system . Toxicol. Sci. 60 (Toxicologist) , : A2032
   Google Scholar
• Machado , M. L. , Beatty , P. W. , Fetzer , J. C , Glickman , A. H. and McGinnis , E. L. 1993 . Evaluation of the relationship between PAH content and mutagenic activity of fumes from roofing and paving asphalts and coal tar pitch [published erratum appears in Fundam.Appl . Toxicol. (1994) 22(2)317]. Fundam. Appl. Toxicol. , 21 : 492 – 499 .
   PubMedGoogle Scholar
• Maizlish , N. , Beaumont , J. and Singleton , J. 1988 . Mortality among California highway workers . Am. J. lnd. Med. , 13 : 363 – 379 .
   Web of Science ®Google Scholar
• Masters , B. S. S. , Williams , C. H. and Kamin , H. 1967 . The preparation and properties of microsomal TPNH-cytochrome creductase from pig liver . Methods Enzymol. , 10 : 565 – 573 .
   Google Scholar
• Matsubara , T. , Prough , R. A. , Burke , M. D. and Estabrook , R. W. 1974 . The preparation of microsomal fractions of rodent respiratory tract and their characterization . Cancer Res. , 34 : 2196 – 2203 .
   PubMed Web of Science ®Google Scholar
• Miles , P. R. , Ma , J. Y. , Bowman , L. and Miller , M. R. 1996 . Pulmonary microsomal metabolism of benzo[a]pyrene following exposure of rats to silica . J. Toxicol. Environ. Health , 48 : 501 – 514 .
   PubMed Web of Science ®Google Scholar
• Monarca , S. , Pasquini , R. , Scassellati , S. G. , Savino , A. , Bauleo , F. A. and Angdi , G. 1987 . Environmental monitoring of mutagenic/carcinogenic hazards during road paving operations with bitumens . Int. Arch. Occup. Environ. Health , 59 : 393 – 402 .
   PubMed Web of Science ®Google Scholar
• Norseth , T. , Waage , J. and Dale , I. 1991 . Acute effects and exposure to organic compounds in road maintenance workers exposed to asphalt . Am. J. Ind. Med. , 20 : 737 – 744 .
   PubMed Web of Science ®Google Scholar
• Partanen , T. and Boffetta , P. 1994 . Cancer risk in asphalt workers and roofers: Review and meta-analysis of epidemiologic studies . Am. J. Ind. Med. , 26 : 721 – 740 .
   PubMed Web of Science ®Google Scholar
• Pott , F. and Heinrich , U. 1990 . Relative significance of different hydrocarbons for the carcinogenic potency of emissions from various incomplete combustion processes . IARC. Sci. Publ. , 104 : 288 – 297 .
   Google Scholar
• Qian , H. W. , Ong , T. and Whong , W. Z. 1996 . Induction of micronuclei in cultured mammalian cells by fume condensates of roofing asphalt . Am. J. Ind. Med. , 29 : 554 – 559 .
   PubMed Web of Science ®Google Scholar
• Qian , H. W. , Ong , T. , Nath , J. and Whong , W. Z. 1998 . Induction of DNA adducts in vivo in rat lung cells by fume condensates of roofing asphalt . Teratogen. Carcinogen. Mutagen. , 18 : 131 – 140 .
   PubMedGoogle Scholar
• Qian , H. , Whong , W. , Olsen , L , Nath , J. and Ong , T. 1999 . Induction of micronuclei in V79 cells by fractions of roofing asphalt fume condensate . Mutat. Res. , 441 : 163 – 170 .
   PubMed Web of Science ®Google Scholar
• Reinke , G. , Swanson , M. , Paustenbach , D. and Beach , J. 2000 . Chemical and mutagenic properties of asphalt fume condensates generated under laboratory and field conditions . Mutat. Res. , 469 : 41 – 50 .
   PubMed Web of Science ®Google Scholar
• Romagna , R and Staniforth , C. D. 1989 . The automated bone marrow micronucleus test . Mutat. Res. , 213 : 91 – 104 .
   PubMed Web of Science ®Google Scholar
• Shimada , T. , Yamazaki , H. , Mimura , M. and Guengerich , F. P. 1992 . Rat pulmonary microsomal cytochrome P-450 enzymes involved in the activation of procarcinogens . Mutat. Res. , 284 : 233 – 241 .
   PubMed Web of Science ®Google Scholar
• Sivak , A. , Niemeier , R. , Lynch , D. , Beltis , K. , Simon , S. , Salomon , R. , Latta , R. , Belinky , B. , Menzies , K. , Lunsford , A. , Cooper , C , Ross , A. and Bruner , R. 1997 . Skin carcinogenicity of condensed asphalt roofing fumes and their fractions following dermal application to mice . Cancer Lett. , 117 : 113 – 123 .
   PubMed Web of Science ®Google Scholar
• Watts , R. R. , Wallingford , K. M. , Williams , R. W. , House , D. E. and Lewtas , J. 1998 . Airborne exposures to PAH and PM2.5 particles for road paving workers applying conventional asphalt and crumb rubber modified asphalt . J. Expos. Anal. Environ. Epidemiol. , 8 : 213 – 229 .
   PubMedGoogle Scholar
• Whitlock , J. P. J. 1999 . Induction of cytochrome P4501A1 . Annu. Rev. Pharmacol. Toxicol. , 39 : 103 – 125 .
   PubMed Web of Science ®Google Scholar
• Zhong , B. Z. , Gu , Z. W. , Stewart , J. and Ong , T. 1995 . Micronucleus formation induced by three polycyclic aromatic hydrocarbons in rat bone marrow and spleen eryth racy tes following intratracheal instillation . Mutat. Res. , 326 : 147 – 153 .
   PubMed Web of Science ®Google Scholar