EFFECTS OF MOTORCYCLE EXHAUST INHALATION EXPOSURE ON CYTOCHROME P-450 2B1, ANTIOXIDANT ENZYMES, AND LIPID PEROXIDATION IN RAT LIVER AND LUNG

REFERENCES

• Esterbauer , H. and Cheeseman , K. H. 1990 . Determination of aldehydic lipid peroxidation products: Malonaldehyde and 4-hydroxynonenal . Methods Enzymol. , 186 : 407 – 421 .
   PubMed Web of Science ®Google Scholar
• Flohë , L. and Günzler , W. A. 1984 . Assays of glutathione peroxidase . Methods Enzymol. , 105 : 114 – 121 .
   PubMed Web of Science ®Google Scholar
• Germansky , M. and Jamall , S. 1988 . Organ-specific effects of naphthalene on tissue peroxidation, glutathione peroxidases, and superoxide dismutase in the rat . Arch. Toxicol. , 61 : 480 – 483 .
   PubMed Web of Science ®Google Scholar
• Guengerich , F. P. , Kim , D.-H. and Iwasaki , M. 1991 . Role of human cytochrome P-450IIE1 in the oxidation of many low molecular weight cancer suspects . Chem. Res. Toxicol. , 4 : 168 – 179 .
   PubMed Web of Science ®Google Scholar
• Gut , I. , Terelius , Y. , Frantik , E. , Linhart , I. , Soucek , P. , Filipcova , B. and Kluckova , H. 1993 . Exposure to various benzene derivatives differently induces cytochromes P450 2B1 and P450 2E1 in rat liver . Arch. Toxicol. , 67 : 237 – 243 .
   PubMed Web of Science ®Google Scholar
• Hricko , A. 1994 . Toxic Taipei traffic . Environ. Health Perspect. , 102 : 279
   Google Scholar
• Jaeschke , H. 1995 . Mechanisms of oxidative stress-induced acute tissue injury . Proc. Soc. Exp. Biol. Med. , 209 : 104 – 111 .
   PubMed Web of Science ®Google Scholar
• Jemma , C. A. , Shore , P. R. and Widdicombe , K. A. 1995 . Analysis of C1–C16 hydrocarbons using dual-column capillary GC: Application to exhaust emissions from passenger car and motorcycle engine . J. Chromatogr. Sci. , 33 : 34 – 48 .
   Web of Science ®Google Scholar
• Kamataki , T. , Kitada , M. , Chiba , K. , Kitagawa , H. , Imai , Y. and Sato , R. 1980 . Enhancement by cyanide of aniline p-hydroxylation activity in rat liver microsomes . Biochem. Pharmacol. , 29 : 1141 – 1147 .
   PubMed Web of Science ®Google Scholar
• Kuo , M.-L. , Jee , S.-H. , Chou , M.-H. and Ueng , T.-H. 1998 . Involvement of oxidative stress in motorcycle exhaust particle-induced DNA damage and inhibition of intercellular communication . Mutat. Res. , 413 : 143 – 150 .
   PubMed Web of Science ®Google Scholar
• Kunsch , C. and Medford , R. M. 1999 . Oxidative stress as a regulator of gene expression in the vasculature . Circ. Res. , 85 : 753 – 766 .
   PubMed Web of Science ®Google Scholar
• Kyle , M. E. , Serroni , A. and Farber , J. L. 1989 . The inhibition of lipid peroxidation by disulfiram prevents the killing of cultured hepatocytes by allyl alcohol, tert-butyl hydroperoxide, hydrogen peroxide and diethyl maleate . Chem. Biol. Interact. , 72 : 269 – 275 .
   PubMed Web of Science ®Google Scholar
• Laemmli , U. K. 1970 . Cleavage of structural proteins during the assembly of the head of bacteriophage T4 . Nature (Lond.). , 227 : 680 – 685 .
   PubMed Web of Science ®Google Scholar
• Liu , X.-F. , Liu , M.-L. , Iyanagi , T. , Legesse , K. , Lee , T. D. and Chen , S. 1990 . Inhibition of rat liver NAD(P)H:quinone acceptor oxidoreductase (DT-diaphorase) by flavonoids isolated from the Chinese herb Scutellariae radix (Huang Qin) . Mol. Pharmacol. , 37 : 911 – 915 .
   PubMed Web of Science ®Google Scholar
• Lowry , O. H. , Rosebrough , N. J. , Farr , A. L. and Randall , R. J. 1951 . Protein determinations with Folin phenol reagent . J. Biol. Chem. , 193 : 265 – 275 .
   PubMed Web of Science ®Google Scholar
• Lubet , R. A. , Mayer , R. T. , Cameron , J. W. , Nims , R. W. , Burke , M. D. , Wolff , T. and Guengerich , F. P. 1985 . Dealkylation of pentoxyresorufin: a rapid and sensitive assay for measuring induction of cytochrome(s) P-450 by phenobarbital and other xenobiotics . Arch. Biochem. Biophys. , 238 : 43 – 48 .
   PubMed Web of Science ®Google Scholar
• Ma , J. Y. C. and Ma , J. K. H. 2002 . The dual effect of the particulate and organic compounds of diesel exhaust particles on the alterations of pulmonary immune/inflammatory responses . J. Environ. Sci. Health C Environ. Carcinogen. Ecotoxicol. Rev. , 20 : 117 – 147 .
   PubMed Web of Science ®Google Scholar
• Mackenzie , P. I. and Hänninen , O. 1980 . A sensitive kinetic assay for UDP-glucuronosyltransferase using 1-naphthol as substrate . Anal. Biochem. , 109 : 362 – 368 .
   PubMed Web of Science ®Google Scholar
• Mauderly , J. L. 1994 . Toxicological and epidemiological evidence for health risks from inhaled engine emissions . Environ. Health Perspect. , 102 (suppl. 4): ) : 165 – 171 .
   PubMed Web of Science ®Google Scholar
• Misra , H. P. and Fridovich , I. 1972 . The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase . J. Biol. Chem. , 247 : 3170 – 3175 .
   PubMed Web of Science ®Google Scholar
• Nadadur , S. S. and Kodavanti , U. P. 2002 . Altered gene expression profiles of rat lung in response to an emission particulate and its metal constituents . J. Toxicol. Environ. Health A. , 65 : 1333 – 1350 .
   PubMed Web of Science ®Google Scholar
• Nebert , D. W. and Gelboin , H. V. 1968 . Substrate-inducible micro somal aryl hydroxylase in mammalian cell culture. I. Assay and properties of induced enzyme . J. Biol. Chem. , 243 : 6242 – 6249 .
   PubMed Web of Science ®Google Scholar
• Nel , A. E. , Diaz-Sanchez , D. , Ng , D. , Hiura , T. and Saxon , A. 1998 . Enhancement of allergic inflammation by the interaction between diesel exhaust particles and the immune system . J. Allergy Clin. Immunol. , 102 : 539 – 554 .
   PubMed Web of Science ®Google Scholar
• Park , S. S. , Fujino , T. , Miller , H. , Guengerich , F. P. and Gelboin , H. V. 1984 . Monoclonal antibodies to phenobarbital-induced rat liver cytochrome P-450 . Biochem. Pharmacol. , 33 : 2071 – 2081 .
   PubMed Web of Science ®Google Scholar
• Park , S. S. , Miller , A. V. , Klotz , A. V. , Klopper-Sams , P. J. , Stegeman , J. J. and Gelboin , H. V. 1986 . Monoclonal antibodies to liver microsomal cytochrome P-450E of the marine fish Stenotomus chrysops (scup): Cross reactivity with 3-methycholanthrene induced rat cytochrome P-450 . Arch. Biochem. Biophys. , 249 : 339 – 350 .
   PubMed Web of Science ®Google Scholar
• Pauluhn , J. 1994 . Validation of an improved nose-only exposure system for rodents . J. Anal. Toxicol. , 14 : 55 – 62 .
   Google Scholar
• Pippenger , C. E. , Browne , R. W. and Armstrong , D. 1998 . Regulatory antioxidant enzymes . Methods Molec. Biol. , 108 : 299 – 313 .
   PubMedGoogle Scholar
• Pohl , A. H. and Fouts , J. R. 1980 . A rapid method for assaying the metabolism of 7-ethoxyresorufin by microsomal subcellular fractions . Anal. Biochem. , 107 : 150 – 155 .
   PubMed Web of Science ®Google Scholar
• Rengasamy , A. , Barger , M. W. , Kane , E. , Ma , J. K. H. , Castranova , V. and Ma , J. Y. C. 2003 . Diesel exhaust particle-induced alterations of pulmonary phase I and phase II enzymes of rats . J. Toxicol. Environ. Health A. , 66 : 153 – 167 .
   PubMed Web of Science ®Google Scholar
• Ryan , D. E. and Levin , W. 1990 . Purification and characterization of hepatic microsomal cytochrome P-450 . Pharmacol. Ther. , 45 : 153 – 239 .
   PubMed Web of Science ®Google Scholar
• Sagai , M. , Saito , H. , Ichinose , T. , Kodama , M. and Mori , Y. 1993 . Biological effects of diesel exhaust particles. I. In vitro production of superoxide and in vivo toxicity in mouse . Free Radical Biol. Med. , 14 : 37 – 47 .
   PubMed Web of Science ®Google Scholar
• Shi , X. , Castranova , V. , Halliwell , B. and Vallyathan , V. 1998 . Reactive oxygen species and silica-induced carcinogenesis . J. Toxicol. Environ. Health B. , 1 : 181 – 197 .
   PubMed Web of Science ®Google Scholar
• Sies , H. 1993 . Strategies of antioxidant defense . Eur. J. Biochem. , 215 : 213 – 219 .
   PubMedGoogle Scholar
• Towbin , H. , Staehelin , T. and Gordon , J. 1979 . Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications . Proc. Natl. Acad. Sci. USA. , 76 : 4350 – 4354 .
   PubMed Web of Science ®Google Scholar
• Tzeng , H.-P. , Yang , R.-S. , Ueng , T.-H. , Lin-Shiau , S. Y. and Liu , S.-H. 2003 . Motorcycle exhaust particulates enhance vasoconstriction in organ culture of rat aortas involve reactive oxygen species . Toxicol. Sci. , 75 : 66 – 73 .
   PubMed Web of Science ®Google Scholar
• Ueng , T.-H. , Ueng , Y.-F. , Chen , T.-L. , Park , S. S. , Iwasaki , M. and Guengerich , F. P. 1993 . Induction of cytochrome P450-dependent monooxygenases in hamster tissues by fasting . Toxicol. Appl. Pharmacol. , 119 : 66 – 73 .
   PubMed Web of Science ®Google Scholar
• Ueng , T.-H. , Hwang , W.-P. , Chen , R.-M. , Wang , H.-W. , Kuo , M.-L. , Park , S. S. and Guengerich , F. P. 1998 . Effect of motorcycle exhaust on cytochrome P450-dependent monooxygenases and glutathione S-transferase in rat tissues . J. Toxicol. Environ. Health A. , 54 : 509 – 527 .
   PubMed Web of Science ®Google Scholar
• Ueng , T.-H. , Hu , S.-H. , Chen , R.-M. , Wang , H.-W. and Kuo , M.-L. 2000 . Induction of cytochrome P450 1A1 in human hepatoma HepG2 and lung carcinoma NCI-H322 cells by motorcycle exhaust particulate . J. Toxicol. Environ. Health A. , 60 : 101 – 119 .
   PubMed Web of Science ®Google Scholar
• Ueng , T.-H. , Wang , H.-W. , Huang , Y.-P. and Hung , C.-C. Antiestrogenic effects of motorcycle exhaust particulate in MCF-7 human breast cancer cells and immature female rats . Arch. Environ. Contam. Toxicol ,
   Web of Science ®Google Scholar
• Vaidyanathan , A. , Foy , J. W.-D. and Schatz , R. A. 2003 . Inhibition of rat respiratory-tract cytochrome P-450 isozymes following inhalation of m-xylene: Possible role of metabolites . J. Toxicol. Environ. Health A. , 66 : 1133 – 1143 .
   PubMed Web of Science ®Google Scholar
• van Eeden , S. F. and Hogg , J. C. 2002 . Systemic inflammatory response induced by particulate matter air pollution: the importance of bone-marrow stimulation . J. Toxicol. Environ. Health A. , 65 : 1597 – 1613 .
   PubMed Web of Science ®Google Scholar
• Wang , H.-W. , Chen , F.-W. and Ueng , T.-H. 2002 . Induction of cytochromes P-450 1A1 and 1B1 by motorcycle exhaust particulate in human breast cancer MCF-7 cells . J. Toxicol. Environ. Health A. , 65 : 1401 – 1417 .
   PubMed Web of Science ®Google Scholar
• Whitekus , M. J. , Li , N. , Zhang , M. , Wang , M. , Horwitz , M. A. , Nelson , S. K. , Horwitz , L. D. , Brechun , N. , Diaz-Sanchez , D. and Nel , A. E. 2002 . Thiol antioxidants inhibit the adjuvant effects of aerosolized diesel exhaust particles in a murine model for ovalbumin sensitization . J. Immunol. , 168 : 2560 – 2567 .
   PubMed Web of Science ®Google Scholar
• Wrighton , S. A. , Thomas , P. E. , Ryan , D. E. and Levin , W. 1987 . Purification and characterization of ethanol-inducible human hepatic cytochrome P-450HLj . Arch. Biochem. Biophys. , 258 : 292 – 297 .
   PubMed Web of Science ®Google Scholar
• Zhou , W. and Ye , S.-H. 1997 . Mutagenicity of scooter exhaust particulate matter . J. Toxicol. Environ. Health. , 52 : 35 – 44 .
   PubMed Web of Science ®Google Scholar