Immunological and Hematological Effects Observed in B6C3F1 Mice Exposed to JP-8 Jet Fuel for 14 Days

REFERENCES

• Aaberge , I. S. and Lovik , M. 1996 . The antibody response after immunization with pneumococcal polysac charide vaccine in splenectomized mice: The effect of re-immunization with pneumococcal antigens . APMIS , 104 : 307 – 317 .
   PubMed Web of Science ®Google Scholar
• Allen , D. C. , Riviere , J. E. and Monteiro-Riviere , N. A. 2000 . Identification of early biomarkers of inflammation produced by keratinocytes exposed to jet fuels jet A, JP-8, and JP-8 (100) . J. Biochem. Mol. Toxicol. , 14 : 231 – 237 .
   PubMed Web of Science ®Google Scholar
• Altman , A. , Mustelin , T. and Coggeshall , K. M. 1990 . T lymphocyte activation: A biological model of signal transduction . Crit. Rev. Immunol. , 10 : 347 – 391 .
   PubMed Web of Science ®Google Scholar
• Aubin , H. J. , Laureaux , C. , Zerah , F. , Tilikete , S. , Vernier , F. , Vallat , B. and Barrucand , D. 1998 . Joint influence of alcohol, tobacco, and coffee on biological markers of heavy drinking in alcoholics . Biol. Psychol. , 44 : 638 – 643 .
   Google Scholar
• Baldwin , C. M. , Houston , F. P. , Podgornik , M. N. , Young , R. S. , Barnes , C. A. and Witten , M. L. 2001 . Effects of aerosolvapor JP-8 jet fuel on the functional observational battery, and learning and memory in the rat . Arch. Environ. Health , 56 : 216 – 226 .
   PubMed Web of Science ®Google Scholar
• Beving , H. , Tornling , G. and Olsson , P. 1991 . Increased erythrocyte volume in car repair painters and car mechanics . Br. J. Ind. Med. , 48 : 499 – 501 .
   PubMedGoogle Scholar
• Boldt , D. H. , MacDermott , R. P. and Jorolan , E. P. 1975 . Interaction of plant lectins with purified human lymphocyte populations: Binding characteristics and kinetics of proliferation . J. Immunol. , 114 : 1532 – 1536 .
   PubMed Web of Science ®Google Scholar
• Bradley , T. R. and Metcalf , D. 1966 . The growth of mouse bone marrow cells in vitro . Aust. J.Exp. Biol. Med. Sci. , 44 : 287 – 300 .
   PubMedGoogle Scholar
• Bryant , J. , Day , R. , Whiteside , T. L. and Herberman , R. B. 1992 . Calculation of lytic units for the expression of cell-mediated cytotoxicity . J. Immunol. Methods , 146 : 91 – 103 .
   PubMed Web of Science ®Google Scholar
• Cohen , G. 1990 . Pulmonary metabolism of foreign compounds: Its role in metabolic activation . Environ. Health Perspect , 85 : 31 – 41 .
   PubMed Web of Science ®Google Scholar
• Crabtree , G. R. 1989 . Contingent genetic regulatory events in T lymphocyte action . Science , 243 : 355 – 361 .
   PubMed Web of Science ®Google Scholar
• Cunningham , J. A. and Szenberg , A. 1968 . Further improvements in the plaque forming technique for detecting single antibody forming cells . Immunology , 14 : 599 – 601 .
   PubMed Web of Science ®Google Scholar
• Davies , N. E. 1964 . Jet fuel intoxication . Aerospace Med. , 35 : 481 – 482 .
   PubMed Web of Science ®Google Scholar
• Dossing , M. , Loft , S. and Schroeder , E. 1985 . Jet fuel and liver function . Scand. J. Work Environ. Health , 11 : 433 – 437 .
   PubMed Web of Science ®Google Scholar
• Dracott , B. N. and Smith , C. E. 1979 . Hydrocortisone and the antibody response in mice. II. Correlations between serum and antibody and PFC in thymus, spleen, marrow and lymph nodes . Immunology , 38 : 437 – 443 .
   PubMed Web of Science ®Google Scholar
• Dudley , A. C. , Peden-Adams , M. , EuDaly , J. and Keil , D. E. 2001a . JP-8 fuel induces CYP2B1, CYP2E1, and GSTPπ but not CYP1A1 in murine liver . Toxicologist , 60 : 405
   Google Scholar
• Dudley , A. C. , Peden-Adams , M. M. , EuDaly , J. , Pollenz , R. S. and Keil , D. E. 2001b . An aryl hydrocarbon receptor independent mechanism of JP-8 jet fuel immunotoxicity in AH-responsive and AH-nonre-sponsive mice . Toxicol. Sci. , 59 : 251 – 259 .
   PubMed Web of Science ®Google Scholar
• Duke , S. S. , Schook , L. B. and Holsapple , M. P. 1985 . Effects of N-nitrodimethylamine on tumor susceptibility . J. Leukocyte Biol. , 37 : 383 – 394 .
   PubMed Web of Science ®Google Scholar
• Glasinovic , J. C. , Lobos , X. , Scrivanti , M. , Severin , M. C. , Quiroga , T. and Moncada , C. 2001 . Carbohydrate deficient transferrin, gammaglutamyl transferase and mean corpuscular volume in the evaluation of recent alcohol intake in excessive drinkers . Rev. Med. Chile , 129 : 375 – 381 .
   PubMed Web of Science ®Google Scholar
• Guo , T. L. , McCay , J. A. , Brown , R. D. , Musgrove , D. L. , Germolec , D. R. , Butterworth , L. , Munson , A. E. and White , K. L. 2000 . Carbon tetrachloride is immunosuppressive and decreases host resistance to Listeria monocytogenes and Streptococcus pneumoniae in female B6C3F1 mice . Toxicology , 154 : 85 – 101 .
   PubMed Web of Science ®Google Scholar
• Harris , D. T. , Sakiestewa , D. , Robledo , R. F. and Witten , M. 1997a . Immunotoxicological effects of JP- 8 jet fuel exposure . Toxicol. Ind. Health , 13 : 43 – 55 .
   PubMed Web of Science ®Google Scholar
• Harris , D. T. , Sakiestewa , D. , Robledo , R. F. and Witten , M. 1997b . Short-term exposure to JP-8 results in long term immunotoxicity . Toxicol. Ind. Health , 13 : 559 – 570 .
   PubMed Web of Science ®Google Scholar
• Harris , D. T. , Sakiestewa , D. , Robledo , R. F. and Witten , M. 1997c . Protection from JP-8 jet fuel induced immunotoxicity by administration of aerosolized substance P . Toxicol. Ind. Health , 13 : 571 – 588 .
   PubMed Web of Science ®Google Scholar
• Harris , D. T. , Sakiestewa , D. , Robledo , R. F. and Witten , M. 2000 . Effects of short-term JP-8 jet fuel exposure on cell-mediated immunity . Toxicol. Ind. Health , 16 : 78 – 84 .
   PubMed Web of Science ®Google Scholar
• Henz , K. 1998 . Survey of jet fuels procured by the Defense Energy Support Center , 1990 – 1996 . Ft. Belvior, VA : Defense Logistics Agencies .
   Google Scholar
• Hirsch , R. , Gress , R. , Pluznik , D. H. , Eckhaus , M. and Bluestone , J. A. 1989 . Effects of in vivo administration of anti-CD3 monoclonal antibody on T cell function in mice. II. In vivo activation of T cells . J. Immunol. , 142 : 737 – 741 .
   PubMed Web of Science ®Google Scholar
• Holsapple , M. P. , White , K. L. , McCay , J. A. , Bradley , S. G. and Munson , A. E. 1988 . An immunotoxicological evaluation of 4,4′-thiobis-(6-t-butyl-m-cresol) in female B6C3F1 mice. Humoral and cell-mediated immunity, macrophage function, and host resistance . Fundam. Appl. Toxicol. , 10 : 701 – 716 .
   PubMedGoogle Scholar
• Hudson , L. and Hay , F. C. , eds. 1989 . “ Hemagglutination ” . In Practical immunology , 3rd , 252 – 254 . Oxford : Blackwell Scientific .
   Google Scholar
• IARC . 1989 . Jet Fuel. Occupational exposures in petroleum refining, crude oil, and major petroleum fuels . IARC Monogr. Eval. Carcinogen. Risks Hum. , 45 : 203 – 218 .
   Google Scholar
• Jerne , N. K. and Nordin , A. A. 1963 . Plaque formation in agar by single antibody producing cells . Science , 140 : 405
   Web of Science ®Google Scholar
• Johnson , C. W. , Williams , W. C. , Copeland , C. B. , DeVito , M. J. and Smialowicz , R. J. 2000 . Sensitivity of the SRBC PFC assay versus ELISA for detection of immunosuppression by TCDD and TCDD-like congeners . Toxicology , 156 : 1 – 11 .
   PubMed Web of Science ®Google Scholar
• Kanikkannan , N. , Jackson , T. , Sudhan Shaik , M. and Singh , M. 2000 . Evaluation of skin sensitization potential of jet fuels by murine local lymph node assay . Toxicol. Lett. , 116 : 165 – 170 .
   PubMed Web of Science ®Google Scholar
• Kim , J. H. , Mun , Y. J. , Chun , H. J. , Jeon , K. S. , Kim , Y. O. and Woo , W. H. 2000 . Effect of biphenyl dimethyl dicarboxylate on the humoral immunosuppression by ethanol . Int. J. Immunopharmacol , 22 : 905 – 913 .
   PubMed Web of Science ®Google Scholar
• Ladics , G. S. , Smith , C. , Heaps , K. and Loveless , S. E. 1994 . Evaluation of the humoral immune response of CD rats following a 2-week exposure to the pesticide carbaryl by the oral, dermal, or inhalation routes . J. Toxicol. Environ. Health , 42 : 143 – 156 .
   PubMed Web of Science ®Google Scholar
• Loveless , S. E. , Ladics , G. S. , Smith , C. , Holsapple , M. P. , Woolhiser , M. R. , Anderson , P. K. , White , K. L. , Musgrove , D. L. , Smialowicz , R. J. and Williams , W. C. 2003 . Interlaboratory study of the primary antibody response to sheep red blood cells in outbred rodents following exposure to dexamethasone . Toxicologist , 72 : 104
   Google Scholar
• Luster , M. I. , Munson , A. E. , Thomas , P. T. , Holsapple , M. P. , Fenters , J. D. , White , K. L. Jr , Lauer , L. D. , Germolec , D. R. , Rosenthal , G. J. and Dean , J. H. 1988 . Development of a testing battery to assess chemical-induced immunotoxicity: National Toxicology Program's guidelines for immunotoxicity evaluation in mice . Fundam. Appl. Toxicol. , 10 : 2 – 19 .
   PubMedGoogle Scholar
• Luster , M. I. , Portier , C. , Pait , D. G. , White , K. L. Jr , Gennings , C. , Munson , A. E. and Rosenthal , G. J. 1992 . Risk assessment in immunotoxicology. I. Sensitivity and predictability of immune tests . Fundam. Appl. Toxicol. , 18 : 200 – 210 .
   PubMedGoogle Scholar
• Midzenski , M. A. , McDiarmid , M. A. , Rothman , N. and Kolodner , K. 1992 . Acute high dose exposure to benzene in shipyard workers . Am. J. Ind. Med. , 22 : 553 – 565 .
   PubMed Web of Science ®Google Scholar
• National Research Council . 2003a . “ Dosimetry and exposure assessment of jet-propulsion fuel 8 ” . In Toxicological assessment of jet-propulsion fuel 8 , 14 – 20 . Washington, DC : National Academy Press .
   Google Scholar
• National Research Council . 2003b . “ Effects of jet-propulsion fuel 8 on the immune system ” . In Toxicological assessment of jet-propulsion fuel 8 , 61 Washington, DC : National Academy Press .
   Google Scholar
• National Toxicology Program . 1994 . Immunotoxicity of atrazine (CAS No. 1912–24–9) in female B6C3F1 mice National Toxicology Program Report IMM94002
   Google Scholar
• National Toxicology Program . 2000 . The immunotoxicity of 3 ′-azido-3′-deoxythymidine (AZT) (CAS No. 30516–87–1) in female B6C3F1 mice National Toxicology Program Report IMM96003
   Google Scholar
• National Toxicology Program . 1989 . 14-Day dose range-finding study for the immunotoxicity evaluation of thalidomide (CAS No. 50–35–1) in Female B6C3F1 mice National Toxicology Program Report IMM96006
   Google Scholar
• National Toxicology Program . 1996 . The immunotoxicity of isoniazid (CAS No. 54–85–3) in female B6C3F1 mice National Toxicology Program Report IMM96012
   Google Scholar
• Navy Occupational Safety and Health Standards Update Board . 1992 . Interim recommendations for permissible fuel exposure criteria from the Navy Environmental Health Center Navy Environmental Health Center Memorandum 6261, Ser. 342514, 9 April
   Google Scholar
• Oosterhuis , W. P. , Niessen , R. W. , Bossuyt , P. M. , Sanders , G. T. and Sturk , A. 2000 . Diagnostic value of the mean corpuscular volume in the detection of vitamin B12 deficiency . Scand. J. Clin. Lab. Invest. , 60 : 9 – 18 .
   PubMed Web of Science ®Google Scholar
• Peden-Adams , M. M. , EuDaly , J. , EuDaly , E. , Dudley , A. , Zeigler , J. , Lee , A. , Robbs , J. , Gilkeson , G. and Keil , D. E. 2001 . Evaluation of immunotoxicity induced by single or concurrent exposure to N, N-diethyl-m-toluamide, pyridostigmine bromide and JP-8 jet fuel . Toxicol. Ind. Health , 17 : 192 – 209 .
   PubMed Web of Science ®Google Scholar
• Pedersen , F. K. , Henrichsen , J. and Schiffman , G. 1982 . Antibody response to vaccination with pneumococcal capsular polysaccharides in splenectomized children . Acta Paediatr. Scand , 71 : 451 – 455 .
   PubMed Web of Science ®Google Scholar
• Pereira , G. M. B. , de , C. , Furtado , G. , Yokoyama , W. M. , Kipnis , T. L. and Shevach , E. M. 1988 . Comparative aspects of T cell activation in vivo with anti-CD3 MAB, allogeneic cells and . Trypanosoma cruzi. Mem. Inst. Oswaldo Cruz. , 83 : 284 – 290 .
   PubMedGoogle Scholar
• Phillips , K. E. , McCay , J. A. , Brown , R. D. , Musgrove , D. L. , Meade , B. J. , Butterworth , L. F. , Wilson , S. , White , K. L. Jr. and Munson , A. E. 1997 . Immunotoxicity of 2’,3’-dideoxyinosine in female B6C3F1 mice . Drug Chem. Toxicol. , 20 : 189 – 228 .
   PubMed Web of Science ®Google Scholar
• Pleil , J. D. , Smith , L. B. and Zelnick , S. D. 2000 . Personal exposure to JP-8 jet fuel vapors and exhaust at air force bases . Environ. Health Perspect. , 108 : 183 – 192 .
   PubMed Web of Science ®Google Scholar
• Rhodes , A. G. , LeMasters , G. K. , Lockey , J. E. , Smith , J. W. , Yiin , J. H. , Egeghy , P. and Gibson , R. 2003 . The effects of jet fuel on immune cells of fuel system maintenance workers . J. Occup. Environ. Med. , 45 : 79 – 86 .
   PubMed Web of Science ®Google Scholar
• Ritchie , G. D. , Rossi , J. 3rd , Nordholm , A. F. , Still , K. R. , Carpenter , R. L. , Wenger , G. R. and Wright , D. W. 2001 . Effects of repeated exposure to JP-8 jet fuel vapor on learning of simple and difficult operant tasks by rats . J. Toxicol. Environ. Health A , 64 : 385 – 415 .
   PubMed Web of Science ®Google Scholar
• Ritchie , G. D. , Still , K. R. , Rossi , J. 3rd , Bekkedal , M. Y. V. , Bobb , A. J. and Arfsten , D. P. 2003 . Biological and health effects of exposure to kerosene-based jet fuels and performance additives . J. Toxicol. Environ. Health B , 6 : 357 – 451 .
   PubMed Web of Science ®Google Scholar
• Rossi , J. , Nordholm , A. F. , Carpenter , R. L. , Ritchie , G. D. and Malcolm , W. 2001 . Effects of repeated exposure of rats to JP-5 or JP-8 jet fuel vapor on neurobehavioral capacity and neurotransmitter levels . J. Toxicol. Environ. Health A , 63 : 397 – 428 .
   PubMed Web of Science ®Google Scholar
• Scharstein , K. , Peden-Adams , M. M. , EuDaly , J. G. and Keil , D. E. 2002 . Comparisons of JP-8-induced immune alterations following two different routes of exposure in female B6C3F1 mice . Toxicologist , 66 ( 1-S ) : 145
   Google Scholar
• Smith , L. B. , Bhattacharya , A. , Lemasters , G. , Succop , P. , Puhala , E. II. , Medvedovic , M. and Joyce , J. 1997 . Effect of chronic low-level exposure to jet-fuel on postural balance of U.S. Air Force personnel . J. Occup. Environ. Med , 39 : 623 – 632 .
   PubMed Web of Science ®Google Scholar
• Temple , L. , Kawabata , T. T. , Munson , A. E. and White , K. L. 1993 . Comparison of ELISA and plaque-forming cell assays for measuring the humoral immune response to SRBC in rats and mice treated with benzo[a]pyrene and cyclophosphamide . Fundam. Appl. Toxicol. , 21 : 412 – 419 .
   PubMedGoogle Scholar
• Ullrich , S. E. 1999 . Dermal application of JP-8 jet fuel induces immune suppression . Toxicol. Sci. , 52 : 61 – 67 .
   PubMed Web of Science ®Google Scholar
• Ullrich , S. E. and Lyons , H. J. 2000 . Mechanisms involved in the immunotoxicity induced by dermal application of JP-8 jet fuel . Toxicol. Sci. , 58 : 290 – 298 .
   PubMed Web of Science ®Google Scholar
• Weiss , A. , Imboden , J. , Hardy , K. , Manger , B. , Terhorst , C. and Stobo , J. 1986 . The role of T3/antigen receptor complex in T cell activation . Annu. Rev. Immunol. , 4 : 593 – 621 .
   PubMed Web of Science ®Google Scholar
• Wiescinski , C. M. , Anderson , P. K. and Holsapple , M. P. 2000 . Characterization of three antibody response models in the mouse: Kinetics and sensitivity to classical immunosuppressants . Toxicologist , 54 : 162
   Google Scholar
• Wilson , S. D. , Munson , A. E. and Meade , B. J. 1999 . Assessment of the functional integrity of the humoral immune response: the plaque-forming cell assay and the enzyme-linked immunosorbent assay . Methods , 19 : 3 – 7 .
   PubMed Web of Science ®Google Scholar
• Witzmann , F. A. , Carpenter , R. L. , Ritchie , G. D. , Wilson , C. L. , Nordholm , F. A. and Rossi , J. III . 2000 . Toxicity of chemical mixtures: proteomic analysis of persisting liver and kidney protein alterations induced by repeated exposure of rats to JP-8 jet-fuel vapor . Electrophoresis , 21 : 2138 – 2147 .
   PubMed Web of Science ®Google Scholar