Characterization of the Metabolic Interaction between Trihalomethanes and Chloroacetic Acids using Rat Liver Microsomes

References

• Amhed , A. E. , Kubic , V. L. and Anders , M. W. 1977 . Metabolism of haloforms to carbon monoxide. II. In vitro studies . Drug Metab. Disposit. , 5 : 198 – 204 .
   PubMedGoogle Scholar
• Amhed , A. E. , Kubic , V. L. , Stevens , J. L. and Anders , M. W. 1980 . Halogenated methanes: Metabolism and toxicity . Fed. Proc. , 39 : 3150 – 3155 .
   PubMedGoogle Scholar
• Brown , D. M. , Langley , P. F. , Smith , D. and Taylor , D. C. 1974 . Metabolism of chloroform. I. The metabolism of [14C]chloroform by different species . Xenobiotica , 4 : 141 – 163 .
   Google Scholar
• Bull , R. J. , Birnbaum , L. S. , Cantor , K. P. , Rose , J. B. , Butterworth , B. E. , Pegram , R. E and Tuomisto , J. 1995 . Symposium overview: Water chlorination: Essential process or cancer hazard? . Fundam. Appl. Toxicol. , 28 : 155 – 166 . [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
   PubMedGoogle Scholar
• Cantor , K. P. 1997 . Drinking water and cancer . Cancer Causes Control , 8 : 292 – 308 . [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Corley , R. A. , Mendrala , A. L. , Smith , F. A. , Staats , D. A. , Gargas , M. L. , Conolly , R. B. , Andersen , M. E. and Reitz , R. H. 1990 . Development of a physiologically based pharmacokinetic model for chloroform . Toxicol. Appl. Pharmacol. , 103 : 512 – 527 . [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Csanady , G. A. , Guengerich , F. P. and Bond , J. A. 1992 . Comparison of the biotransformation of 1,3-butadiene and its metabolite, butadiene monoepoxide, by hepatic and pulmonary tissues from human, rats and mice . Carcinogenesis , 13 : 1143 – 1153 . [PUBMED] [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar
• Da Silva , M. L. , Charest-Tardif , G. , Krishnan , K. and Tardif , R. 1999 . Influence of oral administration of a quaternary mixture of trihalomethane on their blood kinetics in the rat . Toxicol. Lett. , 106 : 49 – 57 . [CROSSREF] [CSA]
   PubMedGoogle Scholar
• Da Silva , M. L. , Charest-Tardif , G. , Krishnan , K. and Tardif , R. 2000 . Evaluation of the pharmacokinetic interactions between orally administered trihalomethanes in the rat . J. Toxicol. Environ. Health A , 60 : 343 – 353 . [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
   PubMedGoogle Scholar
• Davis , M. E. 1992 . Dichloroacetic acid and trichloroacetic acid increase chloroform toxicity . J. Toxicol. Environ. Health , 37 : 139 – 148 . [PUBMED] [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar
• Davis , M. E. and Berndt , W. O. 1992 . Sex differences in monochloroacetate pre-treatment effects on chloroform toxicity in rats . Fundam. Appl. Toxicol. , 18 : 66 – 71 . [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
   PubMedGoogle Scholar
• Gargas , M. L. , Burgess , R. J. , Voisard , D. E. , Cason , G. H. and Andersen , M. E. 1989 . Partition coefficients of low-molecular-weight volatile chemicals in various liquids and tissues . Toxicol. Appl. Pharmacol. , 98 : 87 – 99 . [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Halper , J. R. , Guengerich , F. P. , Bend , J. R. and Correira , M. A. 1994 . Contemporary issues in toxicology. Selective inhibitors of cytochromes P450 . Toxicol. Appl. Pharmacol. , 125 : 163 – 175 . [CROSSREF] [CSA]
   PubMedGoogle Scholar
• Krishnan , K. and Andersen , M. E. 1993 . In vitro toxicology and risk assessement . Alternative Methods Toxicol. , 9 : 185 – 203 . [CSA]
   Google Scholar
• Larson , J. L. and Bull , R. J. 1992 . Metabolism and lipoperoxidative activity of trichloroacetate and dichloroacetate in rats and mice . Toxicol. Appl. Pharmacol. , 115 : 268 – 277 . [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Lieber , C. S. 1997 . Cytochrome P-4502E1: its physiological and pathological role . Physiol. Rev. , 77 : 517 – 544 . [PUBMED] [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Lilly , P. D. , Andersen , M. E. , Ross , T. M. and Pegram , R. A. 1997 . Physiologically based estimation of in vivo rates of bromodichloromethane metabolism . Toxicology , 124 : 141 – 152 . [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Lipscomb , J. C. , Mahle , D. A. , Brashear , W. T. and Barton , H. A. 1995 . Dichloroacetic acid: metabolism in cytosol . Drug Metab. Dispos. , 23 : 1202 – 1205 . [PUBMED] [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Lowry , O. H. , Rosebrough , N. J. , Farr , A. L. and Randall , R. J. 1951 . Protein measurement with the Folin phenol reagent . J. Biol. Chem. , 193 : 265 – 275 . [PUBMED] [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar
• Mathews , J. M. , Troxler , P. S. and Jeffcoat , A. R. 1990 . Metabolism and distribution of bromodichloromethane in rats after single and multiple oral doses . J. Toxicol Environ. Health , 30 : 15 – 22 . [PUBMED] [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar
• McMartin , K. E. and Collins , T. D. 1988 . Distribution of oral 4-methylpyrazole in the rat: inhibition of elimination by ethanol . J. Toxicol. Clin. Toxicol. , 26 : 451 – 466 . [PUBMED] [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Mills , C. J. , Bull , R. J. , Cantor , K. P. , Reif , J. , Hrudey , S. E. and Huston , P. 1998 . Workshop report. Health risks of drinking water chlorination by-products: Report of an expert working group . Chron. Dis. Canada , 19 : 91 – 102 . [CSA]
   PubMedGoogle Scholar
• Nakajima , T. 1997 . Cytochrome P450 isoforms and the metabolism of volatile hydrocarbons of low relative molecular mass . J. Occup. Health , 39 : 81 – 91 .
   Google Scholar
• Nakajima , T. , Wang , R. S. , Murayama , N. and Sato , A. 1990 . Three forms of trichloroethylene-metabolizing enzymes in rat liver induced by ethanol, phenobarbital, and 3-methylcholanthrene . Toxicol. Appl. Pharmacol. , 102 : 546 – 552 . [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
   PubMedGoogle Scholar
• Nakajima , T. , Elovaara , E. , Okino , T. , Gelboin , H. V. , Klockars , M. , Riihimaki , V. , Aoyama , T. and Vainio , H. 1995 . Different contributions of cytochrome P450 2E1 and P450 2B1/2 to chloroform hepatotoxicity . Toxicol. Appl. Pharmacol. , 133 : 215 – 222 . [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Ni , Y.-C. , Wong , T.-Y. , Lloyd , R. V. , Heinze , T. M. , Shelton , S. , Casciano , D. , Kadlubar , F. F. and Fu , P. P. 1996 . Mouse liver microsomal metabolism of chloral hydrate, trichloroacetic acid, and trichloroethanol leading to induction of lipid peroxidation via a free radical mechanism . Drug Metab. Dispos. , 24 : 81 – 90 . [PUBMED] [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Nieuwenhuijsen , M. J. , Toledano , M. B. , Eaton , N. E. , Fawell , J. and Elliott , P. 2000 . Chlorination disinfection byproducts in water and their association with adverse reproductive outcomes: A review . Occup. Environ. Med. , 57 : 73 – 85 . [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Pankow , D. , Damme , B. , Wünsher , U. and Bergmann , K. 1997 . Chlorodibromomethane metabolism to bromide and carbon monoxide in rats . Arch. Toxicol. , 71 : 203 – 210 . [PUBMED] [INFOTRIEVE] [CROSSREF]
   PubMedGoogle Scholar
• Pohl , L. R. , Bhooshan , B. , Whittaker , N. F. and Krishna , G. 1997 . Phosgene: A metabolite of chloroform . Biochem. Biophys. Res. Commun. , 79 : 684 – 691 . [CROSSREF]
   Google Scholar
• Pohl , L. R. , Martin , J. L. and George , J. W. 1980 . Mechanism of metabolic activation of chloroform by rat liver microsomes . Biochem. Pharmacol. , 29 : 3271 – 3276 . [PUBMED] [INFOTRIEVE] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Rook , J. J. 1974 . Formation of haloforms during chlorination of natural waters . Water Treat. Exam. , 23 : 234 – 243 .
   Google Scholar
• Segel , I. H. 1993 . Enzyme kinetics. Behavior and analysis of rapid equilibrium and steady-state enzyme systems , New York : John Wiley & Sons .
   Google Scholar
• Singer , P. C. and Chang , S. D. 1989 . Correlations between trihalomethanes and total organic halides formed during water treatment . J. Am. Water Works Assoc. , 81 : 61 – 65 .
   Web of Science ®Google Scholar
• Stacpoole , P. W. 1989 . The pharmacology of dichloroacetate . Metabolism , 38 : 1124 – 1144 . [PUBMED] [INFOTRIEVE] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• St-Pierre , A. , Krishnan , K. and Tardif , R. 2003 . Evaluation of the influence of chloroacetic acids on the pharmacokinetics of trihalomethanes in the rat . Toxicol. Environ. Health A , 66 : 2267 – 2280 .
   PubMed Web of Science ®Google Scholar
• Testai , E. , De Curtis , V. , Gemma , S. , Fabrizi , L. , Gervasi , P. and Vittozzi , L. 1996 . The role of different cytochrome P450 isoforms in in vitro chloroform metabolism . J. Biochem. Toxicol. , 11 : 305 – 312 . [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
   PubMedGoogle Scholar
• Thornton-Manning , J. R. , Gao , P. , Lilly , P. D. and Pegram , R. A. 1993 . Acute bromodichloromethane toxicity in rats pretreated with cytochrome P450 inducers and inhibitors . Toxicologist , 13 : 360
   Google Scholar
• Williams , D. T. , Lebel , G. L. and Benoit , F. M. 1997 . Disinfection by-products in Canadian drinking water . Chemosphere , 24 : 299 – 316 . [CROSSREF]
   Google Scholar
• Yllner , S. 1971 . Metabolism of chloroacetate-1-14C in the mouse . Acta Pharmacol. Toxicol. , 39 : 69 – 80 .
   Google Scholar