Immunotoxicology of Inhaled Compounds—Assessing Risks of Local Immune Suppression and Hypersensitivity

REFERENCES

• Andersen , I. , Jensen , P. L. , Reed , S. E. , Craig , J. W. , Proctor , D. F. and Adams , G. K. 1977 . Induced rhinovirus infection under controlled exposure to sulfur dioxide . Arch. Environ. Health , 32 : 120 – 125 . [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Aranyi , C. , Bradof , J. N. , O’shea , W. J. , Graham , J. A. and Miller , F. J. 1985a . Effects of arsenic trioxide inhalation exposure on pulmonary antibacterial defenses in mice . J. Toxicol. Environ. Health , 15 : 163 – 172 . [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Aranyi , C. , O’shea , W. J , Sherwood , R. L , Graham , J. A and Miller , F. J . 1985b . Effects of toluene inhalation on pulmonary host defenses of mice . Toxicol. Lett , 25 : 103 – 110 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Aranyi , C. , O’shea , W. J , Graham , J. A and Miller , F. J . 1986 . The effects of inhalation of organic chemical air contaminants on murine lung host defenses . Fundam. Appl. Toxicol , 6 : 713 – 720 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMedGoogle Scholar
• Becker , S. and Soukup , J. M. 1998 . Decreased CD11b expression, phagocytosis, and oxidative burst in urban particulate pollution-exposed human monocytes and alveolar macrophages . J. Toxicol. Environ. Health A , 55 : 455 – 477 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Becker , S. and Soukup , J. M. 1999 . Exposure to urban air particulates alters the macrophage-mediated inflammatory response to respiratory viral infection . J. Toxicol. Environ. Health A , 57 : 445 – 457 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Bernstein , D. I. , Cartier , A. , Cote , J. , Malo , J. L. , Boulet , L. P. , Wanner , M. , Milot , J. , L’Archeveque , J. , Trudeau , C. and Lummus , Z. 2002 . Diisocyanate antigen-stimulated monocyte chemoattractant protein-1 synthesis has greater test efficiency than specific antibodies for identification of diisocyanate asthma . Am. J. Respir. Crit. Care. Med , 166 : 445 – 450 . [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Bernstein , J. A. 1996 . Overview of diisocyanate occupational asthma . Toxicology , 111 : 181 – 189 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Brauer , M. , Hoek , G. , Van Vliet , P. , Meliefste , K. , Fischer , P. H. , Wijga , A. , Koopman , L. P. , Neijens , H. J. , Gerritsen , J. , Kerkhof , M. , Heinrich , J. , Bellander , T. and Brunekreef , B. 2002 . Air pollution from traffic and the development of respiratory infections and asthmatic and allergic symptoms in children . Am. J. Respir. Crit. Care Med , 166 : 1092 – 1098 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Brousseau , P. , Payette , Y. , Tryphonas , H. , Blakley , B. , Boermans , H. , Flipo , D. and Fournier , M. 1999 . Manual of immunological methods , Boca Raton, FL : CRC Press .
   Google Scholar
• Buckley , R. D. and Loosli , C. G. 1969 . Effects of nitrogen dioxide inhalation on germfree mouse lung . Arch. Environ. Health , 18 : 588 – 595 . [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Burleson , G. R. and Keyes , L. L. 1989 . Natural killer activity in Fischer-344 rat lungs as a method to assess pulmonary immunocompetence: Immunosuppression by phosgene inhalation . Immunopharmacol. Immunotoxicol , 11 : 421 – 443 . [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Cartier , A. , Grammer , L. , Malo , J. L. , Lagier , F. , Ghezzo , H. , Harris , K. and Patterson , R. 1989 . Specific serum antibodies against isocyanates: association with occupational asthma . J. Allergy. Clin. Immunol , 84 : 507 – 514 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Chauhan , A. J. and Johnston , S. L. 2003 . Air pollution and infection in respiratory illness . Br. Med. Bull , 68 : 95 – 112 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Chaumard , C. , Quero , A. M. , Bouley , G. , Girard , F. , Boudene , C. and German , A. 1983 . Influence of inhaled cadmium microparticles on mouse influenza pneumonia . Environ. Res , 31 : 428 – 439 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Coffin , D. L. and Gardner , D. E. 1972 . Interaction of biological agents and chemical air pollutants . Ann. Occup. Hyg , 15 : 219 – 235 . [INFOTRIEVE] [CSA]
   PubMedGoogle Scholar
• Davis , J. K. , Davidson , M. K. , Schoeb , T. R. and Lindsey , J. R. 1992 . Decreased intrapulmonary killing of Mycoplasma pulmonis after short-term exposure to NO2 is associated with damaged alveolar macrophages . Am. Rev. Respir. Dis , 145 : 406 – 411 . [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Dearman , R. J. and Kimber , I. 2001 . Cytokine fingerprinting and hazard assessment of chemical respiratory allergy . J. Appl. Toxicol , 21 : 153 – 163 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Dearman , R. J. , Basketter , D. A. , Blaikie , L. , Clark , E. D. , Hilton , J. , House , R. V. , Ladics , G. S. , Loveless , S. E. , Mattis , C. , Sailstad , D. M. , Sarlo , K. , Selgrade , M. K. and Kimber , I. 1998 . The mouse IgE test: Interlaboratory evaluation and comparison of BALB/c and C57BL/6 strain mice . Toxicol. Methods , 8 : 69 – 85 . [CROSSREF] [CSA]
   Google Scholar
• Dearman , R. J. , Betts , C. J. , Humphreys , N. , Flanagan , B. F. , Gilmour , N. J. , Basketter , D. A. and Kimber , I. 2003 . Chemical allergy: Considerations for the practical application of cytokine profiling . Toxicol. Sci , 71 : 137 – 145 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Diaz-Sanchez , D. , Dotson , A. R. , Takenaka , H. and Saxon , A. 1994 . Diesel exhaust particles induce local IgE production in vivo and alter the pattern of IgE messenger RNA isoforms . J. Clin. Invest , 94 : 1417 – 1425 . [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Dockery , D. W. and Pope , C. 1994 . Acute respiratory effects of particulate air pollution . Annu. Rev. Public Health , 15 : 107 – 132 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Ehrlich , R. 1980 . Interaction between environmental pollutants and respiratory infections . Environ. Health Perspect , 35 : 89 – 100 . [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Ehrlich , R. and Henry , M. C. 1968 . Chronic toxicity of nitrogen dioxide. I. Effect on resistance to bacterial pneumonia . Arch. Environ. Health , 17 : 860 – 865 . [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Ehrlich , R. , Findlay , J. C. , Fenters , J. D. and Gardner , D. E. 1977 . Health effects of short-term inhalation of nitrogen dioxide and ozone mixtures . Environ. Res , 14 : 223 – 231 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Fairchild , G. A. 1977 . Effects of ozone and sulfur dioxide on virus growth in mice . Arch. Environ. Health , 32 : 28 – 33 . [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• File , T. M. Jr. 2004 . Streptococcus pneumoniae and community-acquired pneumonia: A cause for concern . Am. J. Med , 117 ( suppl. 3A ) : 39S – 50S . [INFOTRIEVE] [CSA]
   PubMedGoogle Scholar
• Finch , G. 2000 . “ Beryllium ” . In Pulmonary immunotoxicology , Edited by: Cohen , M. , Zelikoff , J. T. and Schlesinger , R. B. 213 – 239 . Boston : Kluwer .
   Google Scholar
• Gilmour , M. I. 1995 . Interaction of air pollutants and pulmonary allergic responses in experimental animals . Toxicology , 105 : 335 – 342 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Gilmour , M. and Jakab , G. 1991 . Modulation of immune function in mice exposed to 0.8 ppm ozone . Inhal. Toxicol , 3 : 293 – 308 . [CSA]
   Google Scholar
• Gilmour , M. I. and Koren , H. 2000 . “ Interaction of inhaled particles with the immune system ” . In Particle–lung interactions , Edited by: Gehr , P. H. 629 – 652 . New York : Marcel Dekker .
   Google Scholar
• Gilmour , M. I. and Selgrade , M. K. 1993 . A comparison of the pulmonary defenses against streptococcal infection in rats and mice following O3 exposure: Differences in disease susceptibility and neutrophil recruitment . Toxicol. Appl. Pharmacol , 123 : 211 – 218 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Gilmour , M. I. , Hmieleski , R. R. , Stafford , E. A. and Jakab , G. J. 1991 . Suppression and recovery of the alveolar macrophage phagocytic system during continuous exposure to 0.5 ppm ozone . Exp. Lung Res , 17 : 547 – 558 . [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Gilmour , M. I. , Park , P. , Doerfler , D. and Selgrade , M. K. 1993a . Factors that influence the suppression of pulmonary antibacterial defenses in mice exposed to ozone . Exp. Lung Res , 19 : 299 – 314 . [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Gilmour , M. I. , Park , P. and Selgrade , M. K. 1993b . Ozone-enhanced pulmonary infection with Streptococcus zooepidemicus in mice. The role of alveolar macrophage function and capsular virulence factors . Am. Rev. Respir. Dis , 147 : 753 – 760 . [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Gilmour , M. I. , Park , P. and Selgrade , M. J. 1996 . Increased immune and inflammatory responses to dust mite antigen in rats exposed to 5 ppm NO2 . Fundam. Appl. Toxicol , 31 : 65 – 70 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMedGoogle Scholar
• Gilmour, M. I., Jaakkola, M. S., London, S. J., Nel, A., and Roger, C. A. 2005. How the outdoor environment influences the incidence and severity of asthma. Environ. Health Perspect Epub April. http://ehp.niehs.nih.gov/docs/2006/8380
   Google Scholar
• Goings , S. A. , Kulle , T. J. , Bascom , R. , Sauder , L. R. , Green , D. J. , Hebel , J. R. and Clements , M. L. 1989 . Effect of nitrogen dioxide exposure on susceptibility to influenza A virus infection in healthy adults . Am. Rev. Respir. Dis , 139 : 1075 – 1081 . [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Griffiths-Johnson , D. A. and Karol , M. H. 1991 . Validation of a non-invasive technique to assess development of airway hyperreactivity in an animal model of immunologic pulmonary hypersensitivity . Toxicology , 65 : 283 – 294 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Harrod , K. S. , Jaramillo , R. J. , Rosenberger , C. L. , Wang , S. Z. , Berger , J. A. , McDonald , J. D. and Reed , M. D. 2003 . Increased susceptibility to RSV infection by exposure to inhaled diesel engine emissions . Am. J. Respir. Cell Mol. Biol , 28 : 451 – 463 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Harrod , K. S. , Jaramillo , R. J. , Berger , J. A. , Gigliotti , A. P. , Seilkop , S. K. and Reed , M. D. 2005 . Inhaled diesel engine emissions reduce bacterial clearance and exacerbate lung disease to Pseudomonas aeruginosa infection in vivo . Toxicol. Sci , 83 : 155 – 165 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Hatch , G. E. , Slade , R. , Boykin , E. , Hu , P. C. , Miller , F. J. and Gardner , D. E. 1981 . Correlation of effects of inhaled versus intratracheally injected males on susceptibility to respiratory infection in mice . Am. Rev. Respir. Dis , 124 : 167 – 173 . [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Henderson , F. W. , Dubovi , E. J. , Harder , S. , Seal , E. Jr. and Graham , D. 1988 . Experimental rhinovirus infection in human volunteers exposed to ozone . Am. Rev. Respir. Dis , 137 : 1124 – 1128 . [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Hilton , J. , Dearman , R. J. , Boylett , M. S. , Fielding , I. , Basketter , D. A. and Kimber , I. 1996 . The mouse IgE test for the identification of potential chemical respiratory allergens: Considerations of stability and controls . J. Appl. Toxicol , 16 : 165 – 170 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Jakab , G. J. 1987 . Modulation of pulmonary defense mechanisms by acute exposures to nitrogen dioxide . Environ. Res , 42 : 215 – 228 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Jakab , G. 1988 . Modulation of pulmonary defense mechanisms against viral and bacterial infections by acute exposure to nitrogen dioxide , Cambridge, MA : Health Effects Research Institute .
   Google Scholar
• Jakab , G. J. 1993 . The toxicologic interactions resulting from inhalation of carbon black and acrolein on pulmonary antibacterial and antiviral defenses . Toxicol. Appl. Pharmacol , 121 : 167 – 175 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Jakab , G. J. and Hmieleski , R. R. 1988 . Reduction of influenza virus pathogenesis by exposure to 0.5 ppm ozone . J. Toxicol. Environ. Health , 23 : 455 – 472 . [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Janeway , C. , Travers , P. , Walport , M. and Shlomchik , M. 2005 . Immunoology, The immune system in health and disease , pp. 517–555. New York : Garland Science .
   Google Scholar
• Karol , M. H. , Macina , O. T. and Cunningham , A. 2001 . Cell and molecular biology of chemical allergy . Ann. Allergy Asthma Immunol , 87 : 28 – 32 . [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Kawabata , T. T. , Babcock , L. S. and Horn , P. A. 1996 . Specific IgE and IgG1 responses to subtilisin Carlsberg (Alcalase) in mice: Development of an intratracheal exposure model . Fundam. Appl. Toxicol , 29 : 238 – 243 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMedGoogle Scholar
• Kirchner , D. B. 2002 . The spectrum of allergic disease in the chemical industry . Int. Arch. Occup. Environ. Health , 75 (suppl.) : S107 – S112 . [INFOTRIEVE] [CROSSREF] [CSA]
   Google Scholar
• Klink , K. J. and Meade , B. J. 2003 . Dermal exposure to 3-amino-5-mercapto-1,2,4-triazole (AMT) induces sensitization and airway hyperreactivity in BALB/c mice . Toxicol. Sci , 75 : 89 – 98 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Lambert , A. L. , Winsett , D. W. , Costa , D. L. , Selgrade , M. K. and Gilmour , M. I. 1998 . Transfer of allergic airway responses with serum and lymphocytes from rats sensitized to dust mite . Am. J. Respir. Crit. Care Med , 157 : 1991 – 1999 . [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Lambert , A. L. , Dong , W. , Winsett , D. W. , Selgrade , M. K. and Gilmour , M. I. 1999 . Residual oil fly ash exposure enhances allergic sensitization to house dust mite . Toxicol. Appl. Pharmacol , 158 : 269 – 277 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Lambert , A. L. , Trasti , F. S. , Mangum , J. B. and Everitt , J. I. 2003 . Effect of preexposure to ultrafine carbon black on respiratory syncytial virus infection in mice . Toxicol. Sci , 72 : 331 – 338 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Lebowitz , M. D. and Fairchild , G. A. 1973 . The effects of sulfur dioxide and A2 influenza virus on pneumonia and weight reduction in mice: An analysis of stimulus-response relationships . Chem. Biol. Interact , 7 : 317 – 326 . [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Lewis , J. 1995 . “ Isolation of alveolar macrophages, peritoneal macrophages, and Kupffer cells ” . In Methods in immunotoxicology , Edited by: Burleson , G. R. D. , Dean , J. H. and Munson , A. E. Vol. 2 , 15 – 38 . New York : Wiley-Liss .
   Google Scholar
• Loosli , C. , Buckley , R. , Hwang-Kow , S. , Hertweck , M. , Hardy , J. and Serebrin , R. 1972 . “ Effect of air pollutant on resistance of mice to airborne influenza A virus infection ” . In Airborne transmission and airborne infection , Edited by: Hass , J. 225 – 231 . Utrecht, the Netherlands : Oosthock .
   Google Scholar
• Maigetter , R. Z. , Ehrlich , R. , Fenters , J. D. and Gardner , D. E. 1976 . Potentiating effects of manganese dioxide on experimental respiratory infections . Environ. Res , 11 : 386 – 391 . [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Mandell , L. A. 2004 . Epidemiology and etiology of community-acquired pneumonia . Infect. Dis. Clin. North Am , 18 : 761 – 776 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Miller , S. and Ehrlich , R. 1958 . Susceptibility to respiratory infections of animals exposed to ozone. I. Susceptibility to Klebsiella pneumoniae . J. Infect. Dis , 103 : 145 – 149 . [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Neldon , D. L. , Lange , R. W. , Rosenthal , G. J. , Comment , C. E. and Burleson , G. R. 1995 . “ Macrophage nonspecific phagocytosis assays ” . In Methods in immunotoxicology , Edited by: Burleson , G. , Dean , J. H. and Munson , A. E. Vol. 2 , 39 – 57 . New York : Wiley-Liss .
   Google Scholar
• NIEHS. 1999. Interagency Coordinating Committee for Validation of Alternative Methods (ICCVAM) Peer review panel evaluation of the murine local lymph node assay (LLNA) report. National Institutes of Health http//iccvam.niehs.nih.gov/methods/llnadocs/llnarep.pdf
   Google Scholar
• Nisizawa , T. , Saito , M. , Nakayama , K. , Nishihara , T. , Imai , S. and Nakagawa , M. 1988 . Effects of nitrogen dioxide on Mycoplasma pulmonis infection and humoral immune responses in mice . Jpn. J. Med. Sci. Biol , 41 : 175 – 187 . [INFOTRIEVE] [CSA]
   PubMedGoogle Scholar
• Park , H. S. , Kim , H. Y. , Nahm , D. H. , Son , J. W. and Kim , Y. Y. 1999 . Specific IgG, but not specific IgE, antibodies to toluene diisocyanate–human serum albumin conjugate are associated with toluene diisocyanate bronchoprovocation test results . J. Allergy Clin. Immunol , 104 : 847 – 851 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Parker , R. F. , Davis , J. K. , Cassell , G. H. , White , H. , Dziedzic , D. , Blalock , D. K. , Thorp , R. B. and Simecka , J. W. 1989 . Short-term exposure to nitrogen dioxide enhances susceptibility to murine respiratory mycoplasmosis and decreases intrapulmonary killing of Mycoplasma pulmonis . Am. Rev. Respir. Dis , 140 : 502 – 512 . [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Plitnick , L. M. , Loveless , S. E. , Ladics , G. S. , Holsapple , M. P. , Smialowicz , R. J. , Woolhiser , M. R. , Anderson , P. K. , Smith , C. and Selgrade , M. J. 2005 . Cytokine mRNA profiles for isocyanates with known and unknown potential to induce respiratory sensitization . Toxicology , 207 : 487 – 499 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Pritchard , R. , Ghio , A. , Lehmann , J. , Winsett , D. , Tepper , J. , Park , P. , Gilmour , M. , Dreher , K. and Costa , D. 1996 . Oxidant generation and lung injury after particulate air pollutant exposure increase with the concentrations of associated metals . Inhal. Toxicol , 8 : 457 – 477 . [CSA]
   Web of Science ®Google Scholar
• Rehm , S. R. , Gross , G. N. and Pierce , A. K. 1980 . Early bacterial clearance from murine lungs. Species-dependent phagocyte response . J. Clin. Invest , 66 : 194 – 199 . [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Robinson , M. K. , Horn , P. A. , Kawabata , T. T. , Babcock , L. S. , Fletcher , E. R. and Sarlo , K. 1998 . Use of the mouse intranasal test (MINT) to determine the allergenic potency of detergent enzymes: comparison to the guinea pig intratracheal (GPIT) test . Toxicol. Sci , 43 : 39 – 46 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Rubinstein , I. , Reiss , T. F. , Bigby , B. G. , Stites , D. P. and Boushey , H. A. Jr. 1991 . Effects of 0.60 PPM nitrogen dioxide on circulating and bronchoalveolar lavage lymphocyte phenotypes in healthy subjects . Environ. Res , 55 : 18 – 30 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Sailstad , D. M. , Ward , M. D. , Boykin , E. H. and Selgrade , M. K. 2003 . A murine model for low molecular weight chemicals: Differentiation of respiratory sensitizers (TMA) from contact sensitizers (DNFB) . Toxicology , 194 : 147 – 161 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Sarlo , K. 1994 . “ Human health risk assessment: Focus on enzymes ” . In Proceedings of the 3rd World Conference on Detergents , Edited by: Cahn , A. 54 – 57 . Chicago : American Oil Chemists Society Press .
   Google Scholar
• Sarlo , K. and Clark , E. D. 1992 . A tier approach for evaluating the respiratory allergenicity of low molecular weight chemicals . Fundam. Appl. Toxicol , 18 : 107 – 114 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMedGoogle Scholar
• Sarlo , K. , Fletcher , E. R. , Gaines , W. G. and Ritz , H. L. 1997 . Respiratory allergenicity of detergent enzymes in the guinea pig intratracheal test: Association with sensitization of occupationally exposed individuals . Fundam. Appl. Toxicol , 39 : 44 – 52 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMedGoogle Scholar
• Saxena , R. K. , Saxena , Q. B. , Weissman , D. N. , Simpson , J. P. , Bledsoe , T. A. and Lewis , D. M. 2003 . Effect of diesel exhaust particulate on bacillus Calmette-Guerin lung infection in mice and attendant changes in lung interstitial lymphoid subpopulations and IFNgamma response . Toxicol. Sci , 73 : 66 – 71 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Schelegle , E. S. , Miller , L. A. , Gershwin , L. J. , Fanucchi , M. V. , Van Winkle , L. S. , Gerriets , J. E. , Walby , W. F. , Mitchell , V. , Tarkington , B. K. , Wong , V. J. , Baker , G. L. , Pantle , L. M. , Joad , J. P. , Pinkerton , K. E. , Wu , R. , Evans , M. J. , Hyde , D. M. and Plopper , C. G. 2003 . Repeated episodes of ozone inhalation amplifies the effects of allergen sensitization and inhalation on airway immune and structural development in Rhesus monkeys . Toxicol. Appl. Pharmacol , 191 : 74 – 85 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Selgrade , M. K. 2000 . Air pollution and respiratory disease: Extrapolating from animal models to human health effects . Immunopharmacology , 48 : 319 – 24 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Selgrade , M. J. K. and Gardner , D. E. 1996 . “ Altered host defenses and resistance to respiratory infections following exposure to airborne metals ” . In Toxicology of metals , Edited by: Chang , T. S. L.W. and Magos , L. 853 – 860 . Boca Raton, FL : CRC Press .
   Google Scholar
• Selgrade , M. J. K. and Gilmour , M. I. 1994 . “ Effects of gaseous air pollutants on immune respomses and susceptibility to infectious and allergic disease ” . In Immunotoxicology and immunopharmacology , Edited by: Dean , J. , Luster , M. I. , Munson , A. E. and Kimber , I. 395 – 411 . New York : Raven Press .
   Google Scholar
• Selgrade , M. J. K. and Gilmour , M. I. 2000 . “ Applying pulmonary immunotoxicity data to risk assessment ” . In Pulmonary immunotoxicology , Edited by: Cohen , M. , Zelikoff , J. T. and Schlesinger , R. B. 411 – 432 . Boston : Kluwer .
   Google Scholar
• Selgrade , M. K. , Illing , J. W. , Starnes , D. M. , Stead , A. G. , Menache , M. G. and Stevens , M. A. 1988 . Evaluation of effects of ozone exposure on influenza infection in mice using several indicators of susceptibility . Fundam. Appl. Toxicol , 11 : 169 – 180 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMedGoogle Scholar
• Selgrade , M. , Starnes , D. , Illing , J. , Daniels , M. and Graham , J. 1989 . Effects of phosgene exposure on bacterial, viral, and neoplastic lung disease susceptibility in mice . Inhal. Toxicol , 1 : 243 – 259 . [CSA]
   Google Scholar
• Selgrade , M. J. K. , Zeiss , C. R. , Karol , M. H. , Sarlo , K. , Kimber , I. , Tepper , J. S. and Henry , M. C. 1994 . Workshop on status of test methods for assessing potential of chemicals to induce respiratory allergenic reactions . Inhal. Toxicol , 6 : 303 – 319 . [CSA]
   Web of Science ®Google Scholar
• Selgrade , M. K. , Cooper , K. D. , Devlin , R. B. , van Loveren , H. , Biagini , R. E. and Luster , M. I. 1995 . Immunotoxicity—Bridging the gap between animal research and human health effects . Fundam. Appl. Toxicol , 24 : 13 – 21 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMedGoogle Scholar
• Sherwood , R. L. , Lippert , W. E. , Tarkington , B. and Goldstein , E. 1981 . Effect of ferrous sulfate aerosols and nitrogen dioxide on murine pulmonary defense . Arch. Environ. Health , 36 : 130 – 135 . [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Sherwood , R. L. , O’shea , W. , Thomas , P. T. , Ratajczak , H. V. , Aranyi , C. C. and Graham , J. A. 1987 . Effects of inhalation of ethylene dichloride on pulmonary defenses of mice and rats . Toxicol. Appl. Pharmacol , 91 : 491 – 496 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Takafuji , S. , Suzuki , S. , Koizumi , K. , Tadokoro , K. , Miyamoto , T. , Ikemori , R. and Muranaka , M. 1987 . Diesel-exhaust particulates inoculated by the intranasal route have an adjuvant activity for IgE production in mice . J. Allergy Clin. Immunol , 79 : 639 – 645 . [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Takenaka , H. , Zhang , K. , Diaz-Sanchez , D. , Tsien , A. and Saxon , A. 1995 . Enhanced human IgE production results from exposure to the aromatic hydrocarbons from diesel exhaust: direct effects on B-cell IgE production . J. Allergy Clin. Immunol , 95 : 103 – 115 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Tasat , D. R. , Mancuso , R. , O’Connor , S. and Molinari , B. 2003 . Age-dependent change in reactive oxygen species and nitric oxide generation by rat alveolar macrophages . Aging Cell , 2 : 159 – 164 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Van Loveren , H. , Krajnc , E. I. , Rombout , P. J. , Blommaert , F. A. and Vos , J. G. 1990 . Effects of ozone, hexachlorobenzene, and bis(tri-n-butyltin)oxide on natural killer activity in the rat lung . Toxicol. Appl. Pharmacol , 102 : 21 – 33 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Viana , M. E. , Coates , N. H. , Gavett , S. H. , Selgrade , M. K. , Vesper , S. J. and Ward , M. D. 2002 . An extract of Stachybotrys chartarum causes allergic asthma-like responses in a BALB/c mouse model . Toxicol. Sci , 70 : 98 – 109 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Wolcott , J. A. , Zee , Y. C. and Osebold , J. W. 1982 . Exposure to ozone reduces influenza disease severity and alters distribution of influenza viral antigens in murine lungs . Appl. Environ. Microbiol , 44 : 723 – 731 . [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Yin , X. J. , Schafer , R. , Ma , J. Y. , Antonini , J. M. , Weissman , D. D. , Siegel , P. D. , Barger , M. W. , Roberts , J. R. and Ma , J. K. 2002 . Alteration of pulmonary immunity to Listeria monocytogenes by diesel exhaust particles (DEPs). I. Effects of DEPs on early pulmonary responses . Environ. Health Perspect , 110 : 1105 – 1111 . [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Yin , X. J. , Dong , C. C. , Ma , J. Y. , Antonini , J. M. , Roberts , J. R. , Stanley , C. F. , Schafer , R. and Ma , J. K. 2004a . Suppression of cell-mediated immune responses to Listeria infection by repeated exposure to diesel exhaust particles in brown Norway rats . Toxicol. Sci , 77 : 263 – 271 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Yin , X. J. , Ma , J. Y. , Antonini , J. M. , Castranova , V. and Ma , J. K. 2004b . Roles of reactive oxygen species and heme oxygenase-1 in modulation of alveolar macrophage-mediated pulmonary immune responses to Listeria monocytogenes by diesel exhaust particles . Toxicol. Sci , 82 : 143 – 153 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Zanobetti , A. , Schwartz , J. and Dockery , D. W. 2000 . Airborne particles are a risk factor for hospital admissions for heart and lung disease . Environ. Health Perspect , 108 : 1071 – 1077 . [PUBMED] [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Zarkower , A. , Scheuchenzuber , W. J. and Burns , C. A. 1979 . Effects of silica dust inhalation on the susceptibility of mice to influenza infection . Arch. Environ. Health , 34 : 372 – 376 . [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Zhang , P. , Summer , W. R. , Bagby , G. J. and Nelson , S. 2000 . Innate immunity and pulmonary host defense . Immunol. Rev , 173 : 39 – 51 . [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar