84
Views
2
CrossRef citations to date
0
Altmetric
Original Articles

Disposition of [14C]N,N-Dimethyl-p-Toluidine in F344 Rats and B6C3F1 Mice

, &
Pages 789-798 | Received 01 May 2006, Accepted 25 Jul 2006, Published online: 17 Apr 2007

REFERENCES

  • Bunn , H. F. and Forget , B. G. 1986 . Hemoglobin: Molecular, genetic, and clinical aspects , 634 – 662 . Philadelphia : W. B. Saunders .
  • ChemFirst Inc . 1997 . Initial submission: Acute inhalation toxicity study of N, N-dimethyl-p-toluidine with MSDS attachment , U.S. EPA/OTS . Doc-88970000118S
  • Druckrey , H. , Schmähl , D. and Reiter , A. 1954 . Lack of carcinogenic activity of three isomers of N-dimethyl-toluidine in the rat (in German) . Arzeim. Forsch. , 4 : 365 – 366 .
  • Dutrée-Meulenberg , R. O. G. M. , Kozel , M. M. A. and Van Joost , T. 1992 . Burning mouth syndrome: A possible etiologic role for local contact hypersensitivity . J. Am. Acad. Dermatol. , 26 : 935 – 940 .
  • Haddad , F. S. , Levell , N. J. , Dowd , P. M. , Cobb , A. G. and Bentley , G. 1995 . Cement hypersensitivity: A cause of aseptic loosening? . J. Bone Joint Surg. , 77-B : 329 – 330 .
  • Haddad , F. S. , Cobb , A. G. , Bentley , G. , Levell , N. J. and Dowd , P. M. 1996 . Hypersensitivity in aseptic loosening of total hip replacements . J. Bone Joint Surg. , 78-B : 546 – 549 .
  • Kaaber , S. , Thulin , H. and Nielson , E. 1979 . Skin sensitivity to denture base materials in the burning mouth syndrome . Contact Dermatitis , 5 : 90 – 96 .
  • Kao , L. , Leikin , J. B. , Crockett , M. and Burda , A. 1997 . Methemoglobinemia from artificial fingernail solution . J. Am. Med. Assoc. , 278 : 549 – 550 .
  • Kim , N.-C. , Katayoon , G. , Kracko , D. A. , Weber , W. M. , McDonald , J. D. and Dix , K. J. 2007 . Identification of Urinary Metabolites of Orally Administered N, N-Dimethyl-p-Toluidine in Male F344 Rats . J. Toxicol. Environ. Health A , 70 : 781 – 788 .
  • Miller , E. G. , Washington , V. H. , Bowles , W. H. and Zimmermann , E. R. 1986 . Mutagenic potential of some chemical components of dental materials . Dent. Mater. , 2 : 163 – 165 .
  • National Library of Medicine. 1999a. RTECS (Registry of Toxic Effects of Chemical Substances). National Institute of Occupational Safety and Health, U.S. Dept. of Health & Human Services, Bethesda, MD. NLM Unique ID 101231980. NLM http://ntp.niehs.nih.gov/ntp/htdocs/Chem_Background/ExSumPdf/DMPT.pdf
  • National Library of Medicine. 1999b. CCRIS (Chemical Carcinogenesis Research Information System), Bethesda, MD, searched April 2002, [Record No. 1001] http://toxnet.nlm.nih.gov
  • National Research Council . 1996 . Guide for the care and use of laboratory animals , 7th , Washington, DC : National Academy Press .
  • National Toxicology Program. 1999. Summary of data for chemical selection, N, N-Dimethyl-p-toluidine http://ntp.niehs.nih.gov/ntp/htdocs/Chem_Background/ExSumPdf/DMPT.pdf
  • National Toxicology Program. 2006. National Toxicology Program Database Search Application http://ntp-apps.niehs.nih.gov/ntp_tox/index.cfm?fuseaction=ntpsearch.searchresults&searchterm=99-97-8
  • Pegam , J. S. and Medhurst , F. A. 1971 . Contact dermatitis from penetration of rubber gloves by acrylic monomer . Br. Med. J. , 2 : 141 – 143 .
  • Potter , J. L. , Krill , C. E. Jr. , Neal , D. and Kofron , W. G. 1988 . Methemoglobinemia due to ingestion of N, N-Dimethyl-p-toluidine, a component used in the fabrication of artificial fingernails . Ann. Emerg. Med. , 17 : 1098 – 1100 .
  • Seto , Y. and Guengerich , F. P. 1993 . Partitioning between N-dealkylation and N-oxygenation in the oxidation of N, N-dialkylarylamines catalyzed by cytochrome P450 2B1 . J. Biol Chem. , 268 ( 14 ) : 9986 – 9967 .
  • Taningher , M. , Pasquini , R. and Bonatti , S. 1993 . Genotoxicity analysis of N, N-dimethylaniline and N, N-dimethyl-p-toluidine . Environ. Mol. Mutagen. , 21 : 349 – 356 .
  • Tosti , A. , Bardazzi , F. , Piancastelli , E. and Brasile , G. P. 1990 . Contact stomatitis due to N, N-dimethyl-para-toluidine . Contact Dermatitis , 22 : 113
  • Verschueren , K. , ed. 1996 . Handbook of environmental data on organic chemicals , 3rd , 842 – 843 . New York : Van Nostrand Reinhold .
  • Verschueren , G. L. A. and Bruynzeel , D. P. 1991 . Allergy to N, N-dimethyl-p-toluidine in dental materials . Contact Dermatitis , 24 : 149

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.