139
Views
18
CrossRef citations to date
0
Altmetric
Original Articles

Effects of Extremely Low-Frequency Electromagnetic Fields on Delayed Chromosomal Instability Induced by Bleomycin in Normal Human Fibroblast Cells

, &
Pages 1252-1258 | Published online: 24 Jul 2007

REFERENCES

  • Antonopoulos , A. , Yang , B. , Stamm , A. , Heller , W. D. and Obe , G. 1991 . Cytological effects of 50 Hz electromagnetic fields on human lymphocyte in vitro . Mutat. Res. , 346 : 151 – 157 .
  • Baum , A. , Mevissen , M. and Kamino , K. 1995 . A histopathological study on alterations in DMBA-induced mammary carcinogenesis in rats with 50 Hz, 100 mT magnetic field exposure . Carcinogenesis , 16 : 119 – 125 .
  • Bunz , F. , Dutriaux , A. , Lengauer , C. , Waldman , T. , Zhou , S. , Brown , J.P. , Sedivy , J. M. , Kinzler , K. W. and Vogelstein , B. 1998 . Requirement for p53 and p21 to sustain G2 arrest after DNA damage . Science. , 282 : 1497 – 1501 .
  • Byrnes , R. W. and Petering , D. H. 1994 . DNA strand breakage in isolated nuclei subjected to bleomycin or hydrogen peroxide . Biochem. Pharmacol. , 48 : 575 – 582 .
  • Chang , W. P. and Little , J. B. 1992 . Evidence that DNA double-strand breaks initiate the phenotype of delayed reproductive death in Chinese hamster ovary cells . Radiat. Res. , 131 : 53 – 59 .
  • Cho , Y. H. and Chung , H. W. 2003 . The effect of extremely low frequency electromagnetic field (ELF-EMF) on the frequency of micronuclei and sister chromatid exchange in human lymphocytes induced by benzo(a)pyrene . Toxicol. Lett. , 143 : 37 – 44 .
  • Dahle , J. and Kvam , E. 2003 . Induction of delayed mutations and chromosomal instability in fibroblasts after UVA-, UVB- and X-radiation . Cancer Res. , 63 : 1464 – 1469 .
  • Duensing , S. and Munger , K. 2001 . Centrosome abnormalities, genomic instability and carcinogenic progression . Biochim. Biophys. Acta , 1471 : M81 – M88 .
  • Fenech , M. 2000 . The in vitro micronucleus technique . Mutat. Res. , 455 : 81 – 95 .
  • Fernie , K. J. , Leonard , N. J. and Bird , D. M. 2000 . Behavior of free-ranging and captive American kestrels under electromagnetic fields . J. Toxicol. Environ. Health A , 59 : 597 – 603 .
  • Fernie , K. J. and Reynolds , S. J. 2005 . The effects of electromagnetic fields from power lines on avian reproductive biology and physiology: A review . J. Toxicol. Environ. Health B , 8 : 127 – 140 .
  • Heim , R. A. , Lench , N. J. and Swift , M. 1992 . Heterozygrous manifestations in our autosomal recessive human cancer-prone syndromes: Ataxia telangiectasia, xeroderma pigmentosum, Fanconi anemia and Bloom syndrome . Mutat. Res. , 284 : 25 – 36 .
  • Huang , L. C. , Clarkin , K. C. and Wahl , G. M. 1996 . Sensitivity and selectivity of the DNA damage sensor responsible for activating p53-dependent G1 arrest . Proc. Natl. Acad. Sci. USA , 93 : 4827 – 4832 .
  • Ivancsits , S. , Pilger , A. , Diem , E. , Jahn , O. and Rüdiger , H. W. 2005 . Cell type-specific genotoxic effects of intermittent extremely low-frequency electromagnetic fields . Mutat. Res. , 583 : 184 – 188 .
  • Juutilainen , J. , Lang , S. and Rytomaa , T. 2000 . Possible cocarcinogenic effects of ELF electromagnetic fields may require repeated long-term interaction with known carcinogenic factors . Bioelectromagnetics , 21 : 122 – 128 .
  • Kadhim , M. A. , Macdonal , D. A. , Goodhead , D. T. , Lorimre , S. A. , Marsden , S. J. and Wright , E. G. 1992 . Transmission of chromosomal instability after plutonium alpha particle irradiation . Nature , 355 : 738 – 740 .
  • Kadhim , M. A. , Lorimore , S. A. , Hepburn , M. D. , Goodhead , D. T. , Buckle , V. J. and Wright , E. G. 1994 . Alpha-particle induced chromosome instability in human bone marrow cells . Lancet , 344 : 987 – 988 .
  • Kaplan , M. I. , Limoli , C. L. and Morgan , W. F. 1997 . Perpetuating radiation-induced chromosomal instability . Radiat. Oncol. Invest. , 5 : 124 – 128 .
  • Kriehuber , R. , Simko , M. , Schiffmann , D. and Trott , K. R. 1999 . Delayed cytotoxic and genotoxic effects in a human cell line following X-irradiation . Int. J. Radiat. Biol. , 75 : 1021 – 1027 .
  • Kryscio , A. , Ulrich Müller , W. U. , Wojcik , A. , Kotschy , N. , Grobelny , S. and Streffer , C. 2001 . A cytogenetic analysis of the long-term effect of uranium mining on peripheral lymphocytes using the micronucleus–centromere assay . Int. J. Radiat. Biol. , 77 : 1087 – 1093 .
  • Lacy-Hulbert , A. , Metcalfe , J. C. and Hesketh , R. 1998 . Biological responses to electromagnetic fields . FASEB J. , 12 : 395 – 420 .
  • Lagroye , I. and Poncy , J. L. 1997 . The effect of 50 Hz electromagnetic fields on the formation of micronuclei in rodent cell lines exposed to gamma radiation . Int. J. Radiat. Biol. , 72 : 249 – 254 .
  • Limoli , C. L. , Kaplan , M. I. , Phillips , J. W. , Adair , G. M. and Morgan , W. F. 1997 . Differential induction of chromosomal instability by DNA strand-breaking agents . Cancer Res. , 57 : 4048 – 4056 .
  • Little , J. B. 2003 . Genomic instability and bystander effects: a historical perspective . Oncogene , 22 : 6978 – 6987 .
  • Little , J. B. , Gorgojo , L. and Vetrovs , H. 1990 . Delayed appearance of lethal and specific gene mutations in irradiated mammalian cells . Int. J. Radiat. Oncol. Biol. Phys. , 19 : 1425 – 1429 .
  • Loescher , W. and Mevissen , M. 1994 . Animal studies on the role of 50/60 Hz magnetic fields in carcinogenesis . Life Sci. , 54 : 1531 – 1543 .
  • Lorimore , S. A. and Wright , E. G. 2003 . Radiation-induced genomic instability and bystander effects: related inflammatory-type responses to radiation-induced stress and injury: A review . Int. J. Radiat. Biol. , 79 : 15 – 25 .
  • Mevissen , M. , Häußler , M. , Lerchl , A. and Löscher , W. 1998 . Acceleration of mammary tumorigenesis by exposure of 7,12-dimethylbenz(a)anthracene–100μT magnetic field: Replication study . J. Toxicol. Environ. Health A , 53 : 401 – 418 .
  • Miller , A. B. , To , T. , Agnew , D. A. , Wall , C. and Green , L. M. 1996 . Leukemia following occupational exposure to 60 Hz electric and magnetic fields among Ontario electric utility workers . Am. J.Epidemiol. , 144 : 150 – 160 .
  • Miller , B. N. , Werner , T. , Weier , H. U. and Nusse , M. 1992 . Analysis of radiation-induced micronuclei by fluorescence in situ hybridization (FISH) simultaneously using telomeric and centromeric DNA probes . Radiat. Res. , 131 : 177 – 185 .
  • Morgan , W. F. 2003 . Is there a common mechanism underlying genomic instability, bystander effects and other nontargeted effects of exposure to ionizing radiation? . Oncogene , 22 : 7094 – 7099 .
  • Morgan , W. F. , Corcoran , J. , Hartmann , A. , Kaplan , M. I. , Limoli , C. L. and Ponnaiya , B. 1998 . DNA double-strand breaks, chromosomal rearrangements, and genomic instability . Mutat. Res. , 404 : 125 – 128 .
  • Morgan , W. F. , Day , J. P. , Kaplan , M. I. , McGhee , E. M. and Limoli , C. L. 1996 . Genomic instability induced by ionizing radiation . Radiat. Res. , 146 : 247 – 258 .
  • Pampfer , S. and Streffer , C. 1989 . Increased chromosome aberration levels in cells from mouse fetuses after zygote X-irradiation . Int. J. Radiat. Biol. , 55 : 85 – 92 .
  • Povirk , L. F. and Austin , M. J. 1991 . Genotoxicity of bleomycin . Mutat. Res. , 257 : 127 – 143 .
  • Purohit , A. , Tynan , S. H. , Vallee , R. and Doxsey , S. J. 1999 . Direct interaction of pericentrin with cytoplasmic dynein light intermediate chain contributes to mitotic spindle organization . J. Cell Biol. , 147 : 481 – 492 .
  • Seymour , C. B. , Mothersill , C. and Alper , T. 1986 . High yields of lethal mutations in somatic mammalian cells that survive ionizing radiation . Int. J. Radiat. Biol. , 50 : 167 – 179 .
  • Sgura , A. , Antoccia , A. , Ramirez , M. J. , Marcos , R. , Tanzarella , C. and Degrassi , F. 1997 . Micronuclei, centromere-positive micronuclei and chromosome nondisjunction in cytokinesis blocked human lymphocytes following mitomycin C or vincristine treatment . Mutat. Res. , 392 : 97 – 107 .
  • Simko , M. , Dopp , E. and Kriehuber , R. 1999 . Absence of synergistic effects on micronucleus formation after exposure to electromagnetic fields and asbestos fibers in vitro . Toxicol. Lett. , 108 : 47 – 53 .
  • Suzuki , K. , Ojima , M. , Kodama , S. and Watanabe , M. 2003 . Radiation-induced DNA damage and delayed induced genomic instability . Oncogene. , 22 : 6988 – 6993 .
  • Tominaga , H. , Kodama , S. , Matsuda , N. , Suzuki , K. and Watanabe , M. 2004 . Involvement of reactive oxygen species (ROS) in the induction of genetic instability by radiation . J. Radiat. Res. (Tokyo). , 45 : 181 – 188 .
  • Walleczek , J. , Shiu , E. C. and Hahn , G. M. 1999 . Increase in radiation-induced HPRT gene mutation frequency after nonthermal exposure to nonionizing 60 Hz electromagnetic fields . Radiat. Res. , 151 : 489 – 497 .
  • Washburn , E. P. , Orza , M. J. , Berlin , J. , Nicholson , W. J. , Todd , A. C. , Frumkin , H. and Chalmers , C. 1994 . Residential proximity to electricity transmission and distribution equipment and risk of childhood leukemia, childhood lymphoma, and childhood nervous system tumors: Systematic review, evaluation, and meta-analysis . Cancer Causes Control , 5 : 299 – 309 .
  • Wertheimer , N. and Lepper , E. 1979 . Childhood cancer in relation to indicators of magnetic fields from current sources . Am. J. Epidemiol. , 109 : 273 – 284 .
  • Wharton , W. 2004 . Repression of G0/G1 traverse in human fibroblasts exposed to low levels of ionizing radiation . J. Biol. Chem. , 279 : 43667 – 43674 .
  • Winker , R. , Ivancsits , S. , Pilger , A. , Adlkofer , F. and Rudiger , H. W. 2005 . Chromosomal damage in human diploid fibroblasts by intermittent exposure to extremely low-frequency electromagnetic fields . Mutat. Res. , 585 : 43 – 49 .
  • Wolf , F. I. , Torsello , A. , Tedesco , B. , Fasanella , S. , Boninsegna , A. , D'Ascenzo , M. , Grass , i. C. , Azzena , G. B. and Cittadini , A. 2005 . 50-Hz extremely low frequency electromagnetic fields enhance cell proliferation and DNA damage: Possible involvement of a redox mechanism . Biochim. Biophys. Acta , 1743 : 120 – 129 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.