Hershberger Assay for Antiandrogenic Effects of Phthalates

REFERENCES

• Adibi , J. J. , Perera , F. P. , Jedrychowski , W. , Camann , D. E. , Barr , D. , Jacek , R. and Whyatt , R. M. 2003 . Prenatal exposures to phthalates among women in New York City and Krakow, Poland . Environ. Health Perspect. , 111 : 1719 – 1722 .
   PubMed Web of Science ®Google Scholar
• Akingbemi , B. T. , Ge , R. , Klinefelter , G. R. , Zirkin , B. R. and Hardy , M. P. 2004 . Phthalate-induced Leydig cell hyperplasia is associated with multiple endocrine disturbances . Proc. Natl. Acad. Sci. USA , 101 : 775 – 780 .
   PubMed Web of Science ®Google Scholar
• Akingbemi , B. T. and Hardy , M. P. 2001 . Oestrogenic and antiandrogenic chemicals in the environment: effects on male reproductive health . Ann. Med. , 33 : 391 – 403 .
   PubMed Web of Science ®Google Scholar
• Andersen , H. R. , Andersson , A. M. , Arnold , S. F. , Autrup , H. , Barfoed , M. , Beresford , N. A. , Bjerregaard , P. , Christiansen , L. B. , Gissel , B. , Hummel , R. , Jorgensen , E. B. , Korsgaard , B. , Le Guevel , R. , Leffers , H. , McLachlan , J. , Moller , A. , Nielsen , J. B. , Olea , N. , Oles-Karasko , A. , Pakdel , F. , Pedersen , K. L. , Perez , P. , Skakkeboek , N. E. , Sonnenschein , C. , Soto , A. M. , Sumpter , J. P. , Thorpe , S. M. and Grandjean , P. 1999 . Comparison of short-term estrogenicity tests for identification of hormone-disrupting chemicals . Environ. Health Perspect. , 107 ( suppl. 1 ) : 89 – 108 .
   PubMed Web of Science ®Google Scholar
• Barlow , N. J. , McIntyre , B. S. and Foster , P. M. 2004 . Male reproductive tract lesions at 6, 12, and 18 months of age following in utero exposure to di(n-butyl) phthalate . Toxicol. Pathol. , 32 : 79 – 90 .
   PubMed Web of Science ®Google Scholar
• Blohm , T. R. , Laughlin , M. E. , Benson , H. D. , Johnston , J. O. , Wright , C. L. , Schatzman , G. L. and Weintraub , P. M. 1986 . Pharmacological induction of 5 alpha-reductase deficiency in the rat: Separation of testosterone-mediated and 5 alpha-dihydrotestosterone-mediated effects . Endocrinology , 119 : 959 – 966 .
   PubMed Web of Science ®Google Scholar
• Carpenter , C. P. , Weil , C. S. and Smyth , H. F. Jr. 1953 . Chronic oral toxicity of di-(2-ethylhexyl) phthalate of rats, guinea pigs, and dogs . AMA Arch. Ind. Hyg. Occup. Med. , 8 : 219 – 226 .
   PubMedGoogle Scholar
• Choi , S. M. , Yoo , S. D. and Lee , B. M. 2004 . Toxicological characteristics of endocrine disrupting chemicals: developmental toxicity, carcinogenicity, and mutagenicity . J. Toxicol. Environ. Health B , 7 : 1 – 24 .
   PubMed Web of Science ®Google Scholar
• David , R. M. , Moore , M. R. , Cifone , M. A . , Finney , D. C. and Guest , D. 1999 . Chronic peroxisome proliferation and hepatomegaly associated with the hepatocellular tumorigenesis of di(2-ethylhexyl) phthalate and the effects of recovery . Toxicol. Sci. , 50 : 195 – 205 .
   PubMed Web of Science ®Google Scholar
• Davis , B. J. , Maronpot , R. R. and Heindel , J. J. 1994 . Di-(2-ethylhexyl) phthalate suppresses estradiol and ovulation in cycling rats . Toxicol. Appl. Pharmacol. , 128 : 216 – 223 .
   PubMed Web of Science ®Google Scholar
• DeRosa , C. , Richter , P. , Pohl , H. and Jones , D. E. 1998 . Environmental exposures that affect the endocrine system: Public health implications . J. Toxicol. Environ. Health B , 1 : 3 – 26 .
   PubMed Web of Science ®Google Scholar
• DiGangi , J. , Schettler , T. , Cobbing , M. and Rossi , M. 2002 . Aggregate exposures to phthalates in humans , Washington, DC : Health Care Without Harm .
   Google Scholar
• EDSTAC, 1998. Endocrine Disruptor Screening and Testing Advisory Committee (EDSTAC) final report, August 1998. U.S. Environmental Protection Agency. In Chapter 5: Screening and Testing: Endocrine Disruptor Screening and Testing Advisory Committee, pp. 1–27. http://www.epa.gov/scipoly/oscpendo/history/finalrpt.htm
   Google Scholar
• Harris , C. A. , Henttu , P. , Parker , M. G. and Sumpter , J. P. 1997 . The estrogenic activity of phthalate esters in vitro . Environ. Health Perspect. , 105 : 802 – 811 .
   PubMed Web of Science ®Google Scholar
• Heindel , J. J. and Powell , C. J. 1992 . Phthalate ester effects on rat Sertoli cell function in vitro: Effects of phthalate side chain and age of animal . Toxicol. Appl. Pharmacol. , 115 : 116 – 123 .
   PubMed Web of Science ®Google Scholar
• Hershberger , L. G. , Shipley , E. G. and Mayer , R. K. 1953 . Myotrophic activity of 19-nortestosterone and other steroids determined by modified levator ani muscle method . Proc. Soc. Exp. Biol. Med. , 83 : 175 – 180 .
   PubMed Web of Science ®Google Scholar
• Hoppin , J. A. , Brock , J. W. , Davis , B. J. and Baird , D. D. 2002 . Reproducibility of urinary phthalate metabolites in first morning urine samples . Environ. Health Perspect. , 110 : 515 – 518 .
   PubMed Web of Science ®Google Scholar
• Houlihan , J. and Wiles , R. 2000 . Beauty secrets. Does a common chemical in nail polish pose risk to human health , Washington, DC : Environmental Working Group .
   Google Scholar
• Jobling , S. , Reynolds , T. , White , R. , Parker , M. G. and Sumpter , J. P. 1995 . A variety of environmentally persistent chemicals, including some phthalate plasticizers, are weakly estrogenic . Environ. Health Perspect. , 103 : 582 – 587 .
   PubMed Web of Science ®Google Scholar
• Kluwe , W. M. , Haseman , J. K. , Douglas , J. F. and Huff , J. E. 1982 . The carcinogenicity of dietary di(2-ethylhexyl) phthalate(DEHP) in Fischer-344 rats and B6C3F1 mice . J. Toxicol. Environ. Health , 10 : 797 – 815 .
   PubMed Web of Science ®Google Scholar
• Koch , H. M. , Drexler , H. and Angerer , J. 2003a . An estimation of the daily intake of di(2-ethylhexyl)phthalate(DEHP) and other phthalates in the general population . Int. J. Hyg. Environ. Health , 206 : 77 – 83 .
   PubMed Web of Science ®Google Scholar
• Koch , H. M. , Gonzalez-Reche , L. M. and Angerer , J. 2003b . On-line clean-up by multidimensional liquid chromatography-electrospray ionization tandem mass spectrometry for high throughput quantification of primary and secondary phthalate metabolites in human urine . J. Chromatogr. B Anal. Technol. Biomed. Life Sci. , 784 : 169 – 182 .
   PubMed Web of Science ®Google Scholar
• Koch , H. M. , Rossbach , B. , Drexler , H. and Angerer , J. 2003c . Internal exposure of the general population to DEHP and other phthalates—Determination of secondary and primary phthalate monoester metabolites in urine . Environ. Res. , 93 : 177 – 185 .
   PubMed Web of Science ®Google Scholar
• Kohn , M. C. , Parham , F. , Masten , S. A. , Portier , C. J. , Shelby , M. D. , Brock , J. W. and Needham , L. L. 2000 . Human exposure estimates for phthalates . Environ. Health Perspect. , 108 : A440 – A442 .
   PubMed Web of Science ®Google Scholar
• Koo , H. J. and Lee , B. M. 2004 . Estimated exposure to phthalates in cosmetics and risk assessment . J. Toxicol. Environ. Health A , 67 : 1901 – 1914 .
   PubMed Web of Science ®Google Scholar
• Koo , H. J. and Lee , B. M. 2005 . Human monitoring of phthalates and risk assessment . J. Toxicol. Environ. Health A , 68 : 1379 – 1392 .
   PubMed Web of Science ®Google Scholar
• Lamb , J. C. 4th , Chapin , R. E. , Teague , J. , Lawton , A. D. and Reel , J. R. 1987 . Reproductive effects of four phthalic acid esters in the mouse . Toxicol. Appl. Pharmacol. , 88 : 255 – 269 .
   PubMed Web of Science ®Google Scholar
• McKinney , J. D. and Waller , C. L. 1998 . Molecular determinants of hormone mimicry: halogenated aromatic hydrocarbon environmental agents. J. Toxicol. Environ. Health . B , 1 : 27 – 58 .
   Google Scholar
• Organization of Economic Cooperation and Development . . 3rd Meeting of the Validation Management Group for the Screening and Testing of Endocrine Disrupters (Mammalian Effects), ENV/JM/TG/EDTA (2001) . Chemicals Committee and the Working Party on Chemicals, Pesticides and Biotechnology . Paris.
   Google Scholar
• Raynaud , J. P. , Bouton , M. M. , Moguilewsky , M. , Ojasoo , T. , Philibert , D. , Beck , G. , Labrie , F. and Mornon , J. P. 1980 . Steroid hormone receptors and pharmacology . J. Steroid Biochem. , 12 : 143 – 157 .
   PubMedGoogle Scholar
• Roy , D. , Palangat , M. , Chen , C. W. , Thomas , R. D. , Colerangle , J. , Atkinson , A. and Yan , Z. J. 1997 . Biochemical and molecular changes at the cellular level in response to exposure to environmental estrogen-like chemicals . J. Toxicol. Environ. Health , 50 : 1 – 29 .
   PubMed Web of Science ®Google Scholar
• Scientific Committee on Cosmetic Products and Non-Food Products. 2002. Opinion of the Scientific Committee on Cosmetic Products and Non-Food Products Intended for Consumers. Concerning diethyl phthalate. http://europa.eu.int/comm/food/fs/sc/sccp/out168_en.pdf]
   Google Scholar
• Sharpe , R. M. 2001 . Hormones and testis development and the possible adverse effects of environmental chemicals . Toxicol. Lett. , 120 : 221 – 232 .
   PubMed Web of Science ®Google Scholar
• Soto , A. M. , Sonnenschein , C. , Chung , K. L. , Fernandez , M. F. , Olea , N. and Serrano , F. O. 1995 . The E-SCREEN assay as a tool to identify estrogens: an update on estrogenic environmental pollutants . Environ. Health Perspect. , 103 ( suppl. 7 ) : 113 – 122 .
   PubMed Web of Science ®Google Scholar
• Tickner , J. A. , Schettler , T. , Guidotti , T. , McCally , M. and Rossi , M. 2001 . Health risks posed by use of di-2-ethylhexyl phthalate (DEHP) in PVC medical devices: A critical review . Am. J. Ind. Med. , 39 : 100 – 111 .
   PubMed Web of Science ®Google Scholar
• Wakeling , A. E. , Furr , B. J. , Glen , A. T. and Hughes , L. R. 1981 . Receptor binding and biological activity of steroidal and nonsteroidal antiandrogens . J. Steroid Biochem. , 15 : 355 – 359 .
   PubMedGoogle Scholar
• Yamasaki , K. , Takeyoshi , M. , Sawaki , M. , Imatanaka , N. , Shinoda , K. and Takatsuki , M. 2003 . Immature rat uterotrophic assay of 18 chemicals and Hershberger assay of 30 chemicals . Toxicology , 183 : 93 – 115 .
   PubMed Web of Science ®Google Scholar
• Yamasaki , K. , Sawaki , M. , Noda , S. , Muroi , T. , Takakura , S. , Mitoma , H. , Sakamoto , S. , Nakai , M. and Yakabe , Y. 2004 . Comparison of the Hershberger assay and androgen receptor binding assay of twelve chemicals . Toxicology , 195 : 177 – 186 .
   PubMed Web of Science ®Google Scholar
• Zacharewski , T. R. , Meek , M. D. , Clemons , J. H. , Wu , Z. F. , Fielden , M. R. and Matthews , J. B. 1998 . Examination of the in vitro and in vivo estrogenic activities of eight commercial phthalate esters . Toxicol. Sci. , 46 : 282 – 293 .
   PubMed Web of Science ®Google Scholar