258
Views
14
CrossRef citations to date
0
Altmetric
Original Articles

Primary Cultures of Human Urothelial Cells for Genotoxicity Testing

, , &
Pages 930-935 | Published online: 04 Jun 2008

REFERENCES

  • Belik , R. , Föllmann , W. , Degen , G. H. , Roos , P. H. , Blaszkewicz , M. , Knopf , H. J. and Golka , K. in press . Improvements in culturing exfoliated urothelial cells in vitro from human urine . J. Toxicol. Environ. Health A ,
  • Bergmeyer , H. U. 1983 . Methods of enzymatic analysis , 3rd , Edited by: Bergmeyer , H. U. , Bergmeyer , J. and Graßl , M. Vol. I–X , Verlag Chemie, FL : Weinheim, and Deerfield Beach .
  • Booth , C. , Harnden , P. , Trejdosiewicz , L. K. , Scriven , S. , Selby , P. J. and Southgate , J. 1997 . Stromal and vascular invasion in an human in vitro bladder cancer model . Lab. Invest. , 76 : 843 – 857 .
  • Cordell , J. L. , Falini , B. , Erber , W. N. , Ghosh , A. K. , Abdulaziz , Z. , Macdonald , S. , Pulford , K. A. , Stein , H. and Mason , D. Y. 1984 . Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase . J. Histochem. Cytochem. , 32 : 219 – 229 .
  • Crallan , R. A. , Georgopoulos , N. T. and Southgate , J. 2006 . Experimental models of human bladder carcinogenesis . Carcinogenesis , 27 : 374 – 381 .
  • Cross , W. R. , Eardley , I. , Leese , H. J. and Southgate , J. 2005 . A biomimetic tissue from cultured normal human urothelial cells: Analysis of physiological function . Am. J. Physiol. Renal Physiol. , 289 : F459 – F468 .
  • Dörrenhaus , A. , Flieger , A. , Golka , K. , Schulze , H. , Albrecht , M. , Degen , G. H. and Föllmann , W. 2000 . Induction of unscheduled DNA synthesis in primary human urothelial cells by the mycotoxin ochratoxin A . Toxicol. Sci. , 53 : 271 – 277 .
  • Flieger , A. , Dörrenhaus , A. , Golka , K. , Schulze , H. and Föllmann , W. 1998 . Genotoxic effect of the mycotoxin ochratoxin A in cultured human urothelial cells . Occup. Hyg. , 4 : 297 – 307 .
  • Föllmann , W. , Guhe , C. , Weber , S. , Birkner , S. and Mähler , S. 2000 . Cultured porcine urinary bladder epithelial cells as a screening model for genotoxic effects of aromatic amines: Characterisation and application of the cell culture model . Altern. Lab. Anim. , 28 : 833 – 854 .
  • Franke , W. W. , Schiller , D. L. , Hatzfeld , M. , Magin , T. M. , Jocarno , J. L. , Mittnacht , S. , Schmid , E. , Cohlberg , J. A. and Quinlan , R. A. 1984 . “ Cytokeratins: Complex formation, biosynthesis, and interactions with desmosomes ” . In The transformed phenotype: The Cancer Cell Meeting held at Cold Spring Harbor in Sept. 1983 , Edited by: Levine , A. J. , VandeWoude , F. G. , Topp , W. C. and Watson , J. D. 177 – 190 . Cold Spring Harbor NY .
  • Franke , W. W. , Schmid , E. , Schiller , D. L. , Winter , S. , Jarasch , E. D. , Moll , R. , Denk , H. , Jackson , B. W. and Illmensee , K. 1982 . “ Differentiation-related patterns of expression of proteins of intermediate size filaments in tissues and cultured cells ” . In Organization of the cytoplasm , Edited by: Cold , Spring Harbor Laboratory . 431 – 453 . Cold Spring Harbor, NY : Cold Spring Harbor Laboratory .
  • Gabrielson , E. W. and Harris , C. C. 1985 . Use of cultured human tissues and cells in carcinogenesis research . J. Cancer Res. Clin. Oncol. , 110 : 1 – 10 .
  • Greim , H. , Arand , M. , Autrup , H. , Bolt , H. M. , Bridges , J. , Dybing , E. , Glomot , R. , Foa , V. and Schulte-Herrmann , R. 2006 . Toxicological comments to the discussion about REACH . Arch. Toxicol. , 80 : 121 – 124 .
  • Guhe , C. , Degen , G. H. , Schuhmacher , U. S. , Kiefer , F. and Föllmann , W. 1996 . Drug metabolizing enzyme activities in porcine urinary bladder epithelial cell cultures (PUBEC) . Arch. Toxicol. , 70 : 599 – 606 .
  • Guhe , C. and Föllmann , W. 1994 . Growth and characterization of porcine urinary bladder epithelial cells in vitro . Am. J. Physiol. , 266 : F298 – F308 .
  • Hengstler , J. G. , Arand , M. , Herrero , M. E. and Oesch , F. 1998 . Polymorphisms of N-acetyltransferases, glutathione S-transferases, microsomal epoxide hydrolase and sulfotransferases: Influence on cancer susceptibility . Rec. Res. Cancer Res. , 154 : 47 – 85 .
  • Hijazi , A. , Devonec , M. , Bouvier , R. and Revillard , P. 1989 . Flow cytometry study of cytokeratin 18 expression according to tumor grade and deoxyribonucleic acid content in human bladder tumours . J. Urol. , 141 : 522 – 526 .
  • Holstein , A.F. , Sandmann , J. , Bresse , l. M. and Davidof , M.S. 1994 . Reinvestigation of the transitional epithelium (urothelium) of the human ureter . Ann. Anat. , 176 : 109 – 117 .
  • Huff , J. 1999 . Chemicals associated with tumours of the kidney, urinary bladder and thyroid gland in laboratory rodents from 2000 US National Toxicology Program/National Cancer Institute bioassays for carcinogenicity . IARC Sci. Publ. , 147 : 211 – 225 .
  • Jauregui , H.O. , Hayner , N.T. , Driscoll , J.L. , Williams-Holland , R. , Lipsky , M. H. and Galletti , P.M. 1981 . Trypan blue uptake and lactate dehydrogenase in adult hepatocytes, freshly isolated cells, cell suspensions and primary monolayer cultures . In Vitro , 17 : 1100 – 1110 .
  • Kurec , A. S. , Baltrucki , L. , Mason , D. Y. and Davey , F. R. 1988 . Use of the APAAP method in the diagnosis of hematologic disorders . Clin. Lab. Med. , 7 : 223 – 236 .
  • Lebrun , S. , Golka , K. , Schulze , H. and Föllmann , W. 2006 . Glutathione S-transferase polymorphisms and ochratoxin A toxicity in primary human urothelial cells . Toxicology , 224 : 81 – 90 .
  • Mähler , S. , Kinne-Saffran , E. , Fujisue , H. , Kinne , R. K. and Föllmann , W. 1998 . Regulation of sorbitol content in cultured porcine urinary bladder epithelial cells . Am. J. Physiol. , 274 : F342 – F347 .
  • Messing , E. M. 2002 . “ Urothelial tumors of the urinary tract ” . In Campbell´s urology , 8th , Edited by: Walsh , P. C. , Retik , A. , Vaughan , E. D. and Wein , A. J. Vol. 4 , 2732 – 2784 . Philadelphia : Saunders .
  • Moll , R. , Achtstätter , T. , Becht , E. , Balcarova-Ständer , J. , Ittensohn , M. and Franke , W. W. 1988 . Cytokeratins in normal and malignant transitional epithelium . Am. J. Pathol. , 132 : 123 – 144 .
  • Moll , R. 1993 . Cytokeratins as markers of differentiation. Expression profiles in epithelia and epithelial tumors . Veröff. Pathol. , 142 : 1 – 197 . (in German)
  • Moll , R. 1994 . Cytokeratins in the histological diagnosis of malignant tumors . Int. J. Biol. Markers , 9 : 63 – 69 .
  • Raghavan , D. , Debruyne , F. , Herr , H. , Jocham , D. , Kakizoe , T. , Okajima , E. , Sandberg , A. and Tannock , I. 1986 . Experimental models of bladder cancer: A critical review . Prog. Clin. Biol. Res. , 221 : 171 – 208 .
  • Ramaekers , F. , Huysmans , A. , Moesker , O. , Schaart , G. , Herman , C. and Vooijs , P. 1985 . Cytokeratin expression during neoplastic progression of human transitional cell carcinomas as detected by a monoclonal and polyclonal antibody . Lab. Invest. , 52 : 31 – 38 .
  • Reedy , E. A. , Heatfield , B. M. , Trump , B. F. and Resau , J. H. 1990a . Correlation of cytokeratin patterns with histopathology during neoplastic progression in the rat urinary bladder . Pathobiology , 58 : 15 – 27 .
  • Reedy , E. A. , Colombo-Burke , K. L. and Resau , J. H. 1990b . Discrimination of cell types in primary transitional cell carcinoma by monoclonal anti-cytokeratin antibodies . Pathobiology , 58 : 304 – 311 .
  • Southgate , J. , Varley , C. L. , Garthwaite , M. A. , Hinley , J. , Marsh , F. , Stahlschmidt , J. , Trejdosiewicz , L. K. and Eardley , I. 2007 . Differentiation potential of urothelium from patients with benign bladder dysfunction . Br. J. Urol. Int. , 99 : 1506 – 1516 .
  • Wilbourn , J. D. , Partensky , C. and Rice , J. M. 1999 . Agents that induce epithelial neoplasms of the urinary bladder, renal cortex and thyroid follicular lining in experimental animals and humans: Summary of data from IARC monographs volumes 1–69 . IARC Sci. Publ. , 147 : 191 – 209 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.